Ask the Doctor with Dr. Michael Lange from 03-26-16 LM

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Ask the Doctor Radio Show from 2-6-16 with Dr. Michael Lange

Ask the Doctor Radio Show from 01-09-16 with Dr. Michael Lange

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Nutrition, Macular Pigments and AMD

The role of lutein and zeaxanthin supplements in nutrition, as discussed by leading optometrists, and their effects on macular degeneration and macular pigments. Taking lutein, zeaxanthin and dark green leafy vegetables such as spinach and kale can help with ocular nutrition. Caution is recommended for those with kidney stones or using blood thinners. Comments by Dr. Michael Lange OD CNS, certified nutrition specialist.

Increased levels of zeaxanthin and lutein can reduce the risk of AMD.
But just how much is needed and, how do we measure results?

Tara Rosenzweig, Contributing Editor for Optometric Management magazine

It’s commonly understood: Levels of the macular pigments lutein and zeaxanthin correlate to agerelated macular degeneration risk (AMD). So, as a measure of prevention, should optometrists recommend dietary and supplemental intake of these important nutrients — carotenoids that protect against phototoxic blue light and near-ultraviolet radiation and which are found naturally in the macula?

And if so:

How much of each is needed?
Should the nutrients come from food, supplements or a combination of both?
How can you determine the success of a supplement program? Should you consider the use of devices that measure the macular pigment optical density (MPOD)?

Here, experts on ocular nutrition and MPOD-measurement devices weigh in on these, among other common questions.

How much is enough?

It’s difficult for healthcare professionals and patients to know just how much lutein and zeaxanthin should be consumed on a daily basis. Supplements with lutein and zeaxanthin vary in nutrient content and packaging. For instance, they often accompany vitamins and nutrients, such as vitamins A, C, and E and zinc. And because no recommended daily intake for these nutrients exists, many O.D.s aren’t sure how much to recommend for optimal macular health benefits.

“In general, normal lutein/zeaxanthin supplements average in the 15 mg to 20 mg (range) for lutein and 2 mg to 4 mg for zeaxanthin,” says Jeffrey Anshel, O.D., F.A.A.O., president of the Ocular Nutrition Society. “Some supplement companies add more, but most of the science points to about these amounts.”

He adds the caveat: “Since lutein is sequestered in fat tissue, different patients may require different amounts.”

There’s no exact number, explains Paul S. Bernstein, M.D., Ph.D., Mary Boesche professor of Ophthalmology and Visual Sciences at Moran Eye Center at the University of Utah School of Medicine in Salt Lake City. “Based on epidemiology and studies on risk of macular degeneration, it’s generally come up somewhere between 6 mg and 10 mg [of each] a day. Those are the reasonable numbers.”

Dr. Bernstein and others say they hope that tests of 10 mg of lutein and 2 mg of zeaxanthin in the second Age Related Eye Disease Study (AREDS2) study will provide a definitive answer.

Michael Lange, O.D., C.N.S. (certified nutrition specialist), who owns Lange Eye Care and Associates in Florida and also founded Fortifeye Vitamins, recommends dosages by age and health status. For most patients, he says he advises 6 mg to 10 mg of lutein and 1 mg to 2 mg of zeaxanthin daily. But for patients with early-to-moderate AMD, he says he recommends 10 mg to 20 mg of lutein and 2 mg to 4 mg of zeaxanthin daily. For moderate-to-advanced AMD, he says he recommends 20 mg to 30 mg of lutein and 4 mg to 6 mg of zeaxanthin.

But are lutein and zeaxanthin equally important?

The answer is unknown, says Elizabeth Johnson, Ph.D., with the Carotenoids and Health Laboratory of the Jean Mayer United States Department of Agriculture (USDA) Human Nutrition Research Center on Aging at Tufts University in Boston. She points to interesting data.

“Work that we conducted here shows definitively that of the zeaxanthin in the retina, about half of that is actually derived from lutein,” she says.

From food or supplements?

Recommended dosages of the nutrients can be absorbed from food or supplements, but some experts say it’s unlikely many patients will derive lutein and zeaxanthin from diet alone.

Kimberly Reed, O.D., F.A.A.O., associate professor at the College of Optometry at Nova Southeastern University in Fort Lauderdale, Fla., and a member of the Nutrition Ocular Society’s board of directors, says sufficient amounts of the nutrients would be difficult to amass from the typical Western diet.

“This is where patient education is essential,” Dr. Reed says.

A look at quantities of lutein in foods sheds light on how difficult levels experts recommend may be to reach, she explains. While dark leafy greens, like spinach and kale, abound with lutein at 20.4 mg and 23.7 mg per cooked cup, respectively, other foods considered good lutein sources contain far less. For example, corn and green beans — consumed more often than spinach and kale — contain just 1.5 mg and 0.9 mg per cooked cup, which presents a recommended-dosage shortfall if dark leafy vegetables aren’t also consumed, according to the Lutein Information Bureau (www.luteininfo.com) and the USDA’s Nutrient Database.

Dr. Johnson adds that patients who can’t eat green leafy vegetables because they’re on blood thinners or have a propensity toward kidney stones may benefit from lutein and zeaxanthin supplements.

Dr. Lange says he also believes in starting with diet and supplementing only if necessary.

“I will … tell my patients who aren’t on blood thinners and do not have kidney stones or gout to eat one-half-to-one-cup of dark green leafy vegetables a day,” he says.

But, Dr. Lange explains that even people with specific lutein and zeaxanthin restrictions usually don’t obtain sufficient amounts of lutein and zeaxanthin from their daily diet. This may be particularly true for the elderly, who may have limited access to shopping outlets, he says. They may need supplements, which Lange recommends “as an insurance policy for anyone with AMD.”

When should patients start?

At what age should patients start taking lutein and zeaxanthin supplementation, either through diet or supplements? Some experts suggest that people who have low MPOD should begin supplementation in their 20s. Our experts weren’t so sure.

“We know that interventions for macular degeneration are important when people are in the middle stages of macular degeneration,” Dr. Bernstein says.

When it comes to younger people with a family history of AMD, it’s more difficult to make recommendations, he adds.

“Patients have to realize the data are not as strong if they’re in their 20s and 30s,” he says. “I, in my practice as a macular degeneration specialist, counsel them most importantly to achieve a good, healthy diet: dark green, leafy vegetables and orange and yellow fruits and vegetables.”

Dr. Johnson adds that younger patients are most at risk for light damage and should know the importance lutein- and zeaxanthin-rich foods.

“The younger people are those who have the clear lens, and that makes the retina more vulnerable to light damage from being outdoors more often,” she says.

Supplements: How far should O.D.s go?

Should O.D.s recommend, or sell, lutein and zeaxanthin supplements to patients? Our experts say, “Yes,” with care and diligence.

“I make recommendations on supplements … and have them available as a convenience — just like I do glasses and contact lenses,” Dr. Anshel says. “There are several factors that the doctor must consider when evaluating a nutritional supplement, including knowing the science behind the ingredients and having a company that is third-party GMP (Good Manufacturing Practices) certified.”

The decision to recommend or sell supplements largely depends on the O.D.’s personal preference, Dr. Reed says, stressing responsibility.

“Many optometrists prefer to avoid the ‘retail’ end of nutrition, while others have seamlessly incorporated this into their already successful retail business,” she says.

She cautions that it is paramount that optometrists who begin nutritional counseling or retailing, or both, be properly educated on the topics and remain up-to-date on nutrition and the eye.

Dr. Lange recommends offering patients a whole-body supplement with enough lutein/zeaxanthin, along with various other vitamins, minerals, wholefood complexes and omega-3 essential fatty acids.

“Lutein and zeaxanthin are only two pieces of the puzzle,” Dr. Lange says, adding that optometrists should take nutrition courses and consider becoming a certified nutrition specialist (CNS) for confidence in helping patients with nutrition.

Measuring results

Of the methods used to measure MPOD, optometrists are likely most familiar with commercially available heterochromatic flicker photometry (HFP) devices. The authors of a recent review article in Clinical and Experimental Optometry (September 2010) write that due to concerns regarding the repeatability of test results, they recommend clinicians exercise caution when considering these instruments to monitor MPOD in patients who are taking lutein and zeaxanthin supplements.

Dr. Bernstein agrees with this conclusion, noting that HFP is a subjective test that is difficult for many people, even well-trained professionals, to use. He adds that often the operator or patient is not trained adequately in these devices.

“If you don’t have proper training, you’re going to get results that don’t mean very much,” he says.

So, should optometrists purchase and use the HFP devices to assess MPOD in patients? Dr. Bernstein answers “yes,” “with a healthy dose of caution.” He encourages optometrists to try the devices to determine reproducibility in their practices.

The vendors of the HFP measuring devices may also be able to lend assistance in this area as they offer training on the devices.

Dr. Anshel recommends taking a scientific approach to the devices — the same approach you would take when considering the acquisition of any diagnostic device.

“Choosing a measuring device should be based on the doctor’s confidence in using the device to obtain scientific information about macular pigment and not just for ‘marketing’ a nutritional approach,” he says.

Other MPOD-measurement tools — currently available only for research — may become more widely available, says Dr. Bernstein. Methods that could hold promise include more image-based ones, such as autofluorescence, Raman spectroscopy, and reflectometry.

Dr. Reed says clinicians also need to understand the limits of MPOD testing.

“MPOD testing is really measuring the levels of lutein and zeaxanthin in the macula, and we need to use caution when making the leap between macular pigment and AMD,” she says. “Certainly there is a strong association, but it may not be quite as linear as it would initially appear to be.”

Dr. Lange says he uses a blood test to see concentration in ug/l of lutein and zeaxanthin to help determine what dietary and supplement adjustments a patient needs.

Dr. Anshel raises another point in measuring these carotenoids: “Since lutein is sequestered in fat tissue, patient body mass index might be a factor in how much lutein is actually transferred to the eye.”

He adds that conversion of lutein to meso-zeaxanthin may also be an issue.

“Meso-zeaxanthin is converted from lutein by an enzyme, which needs to be present,” he says. “While we assume that it is, we have no way of being certain. This is relatively new science, so establishing a baseline might take more time.”

The bottom line: Be careful, and be educated

While the science is new and more research is needed, those interviewed for this article agree that with the proper education, optometrists can counsel patients on the relationship between nutrition and supplements, AMD and other eye diseases. An O.D.’s recommendation may also improve the overall care of the patient.

Says Dr. Lange: “I see it every day in clinical practice where we have made dietary and supplemental recommendations, and patients’ ocular health and overall health can improve dramatically.”

This article was originally published in the December 2010 issue of Optometric Management Magazine.

 

Lange Eye Care Locations

Gainesville Office
Lange Eye Care and Associates
3968 SW Archer Road W101
Gainesville, Florida 32608
Phone: 352-376-6622

Ocala Office
Lange Eye Care and Associates
3101 SW College Road
Ocala, Florida 34474
Phone: 352-237-3768

Triple Crown Plaza Office
Lange Eye Care and Associates
11100 SW 93rd Court Road
Suite 15
Ocala, Florida 34481
Phone: 352-291-2000

Summerfield Office
Lange Eye Care Vision Outlet Center
Unit #604 Highway 441S
Summerfield, Florida
Phone: 352-307-3273

Inverness Office
Lange Eye Care and Associates
3808 E. Gulf to Lake Highway
Inverness, FL 34453
Phone: 352-344-5110

Clearwater Offices
Lange Eye Care Optical Gallery & LASIK Center
23666 U. S. Highway 19 North
Clearwater, FL 33765
Phone: 727-791-1214

Lange Sun and Nutrition Center
2551 Drew Street
Suite 302
Clearwater, FL 33765
Phone: 727-216-6275

Williston Office
Lange Eye Care And Associates
129 S. W. 7th Street
Williston, FL 32696
Phone: 352-528-0433

The Villages Office
Lange Eye Institute
466 and CR101
The Villages, Florida
Phone: 352-753-4014

 

 

 

 

Map and Directions


View Larger Map

 

More information: Dr. Michael P. Lange is a Board Certified Optometric Physician and a Certified Nutrition Specialist who started Lange Eye Care and Associates in Ocala, Florida, in March 1993. Lange Eye Care has grown to nine locations throughout the state of Florida with three Lasik centers. The Lange Eye Institute at The Villages in central Florida is home base for many of the nutritional studies that Fortifeye is involved in. Dr. Lange is one of the first doctors in the industry to utilize intracellular blood tests and blood absorption studies to improve the Fortifeye vitamin line. Dr. Lange travels the world for nutritional research gathering valuable information to continuously improve Fortifeye vitamin formulations. Dr. Lange is still involved in the clinical practice of eyecare. He is a guest lecturer, contributing author to many eyecare magazines, and a daily syndicated talk show host of ‘Ask The Doctor’ which broadcasts every weekday at 9am and Saturdays at 2pm from Tampa Bay on radio stations throughout the country and video streaming all over the world via the Internet.

 

 

 

 

Order Fortifeye™ vitamins by clicking below:

 

Fortifeye Complete Plus | Click To Order
Fortifeye Complete Plus | Click To Order
Fortifeye™ Complete Plus

Fortifeye™ Complete Plus is an advanced formulation based on the latest clinical studies. It is a combination of synergistically blended whole foods, phytonutients, vitamins, minerals, enzymes and essential fatty acids. When combined with proper diet, exercise and a healthy life style Fortifeye™ Complete Plus lays the foundation for good eye and total body health.

Dosage: 2 tablets + 1 softgel/day
30 Packs per box. Each daily pack contains 2 tablets and 1 softgel
Best price on the Internet! $50.00
Fortifeye Complete Plus | Click To Order

Fortifeye Super Omega-3 Fish Oil | Click To Order
Fortifeye Super Omega-3 Fish Oil
Fortifeye™ Super Omega 3 Fish Oil

Fortifeye™ Super Omega-3 Fish Oil is the newest, most concentrated and purified Omega Three Fish Oil by Fortifeye™
Features: Natural Triglyceride Form • Molecularly Distilled for Maximum Purity • High Potency/Triple Strength • Natural Orange/ Lemon Flavor • Pharmaceutical Grade • Superior taste • No unpleasant odor • Unsurpassed purity (Triple Molecular distillation) • Produced in Norway in the world’s only NSF, GMP certified Omega 3 production facility
Promotes: Heart Health • Brain Health • Eye Health • Joint Health • Circulation • Good Blood Pressure • Healthy Cholesterol • Improved Triglycerides • Skin, Hair & Nail Health • Mental & Cognitive Health

Take Fortifeye™ Super Omega-3 in conjunction with Fortifeye™ Complete Plus for more intensive nutritional therapy.

Dosage: 2 softgels/day
60 softgels/bottle
Best price on the Internet! $25.00
Fortifeye Super Omega-3 Fish Oil | Click To Order

Fortifeye FOCUS | Click To Order
Fortifeye FOCUS | Click To Order
Fortifeye™ FOCUS

Fortifeye™ FOCUS is a combination of three carotenoids—astaxanthin, lutein and zeaxanthin. Clinical studies indicate that 6mg of astaxanthin reduces eye fatigue symptomology and actually improves amplitude of accommodation, the eye’s ability to focus clearly on objects at near distances. This new formulation was developed to help reduce accommodative stress due to prolonged working at a near focal length. Fortifeye FOCUS is recommended for individuals who experience eye fatigue with near point tasks or after prolonged work on a computer. Fortifeye FOCUS can be used alone or in combination with any of the Fortifeye™ Vitamins.

Dosage: 1 softgel per day
30 softgels per bottle.
Best price on the Internet! $25.00
Fortifeye FOCUS | Click To Order

Fortifeye Complete One-A-Day | Click To Order
Fortifeye Complete One-A-Day | Click To Order
Fortifeye™ Complete
One-A-Day Multivitamin

Fortifeye™ Complete One-A-Day is a powerhouse combination of 50 total body and vision specific nutrients all combined into one USP certified tablet. Fortifeye™ Complete One-A-Day multivitamin has been created by doctors who understand that quality counts. Fortifeye™ Complete One-A-Day can be used alone or in combination with Fortifeye™ Super Omega 3 Fish Oil or Fortifeye™ Dry Eye Therapy Extreme to combat against free radical damage in the eyes and body.

Dosage: 1 tablet per day
30 tablets per bottle.
Best price on the Internet! $25.00
Fortifeye Complete One-A-Day | Click To Order

Fortifeye Complete Macular Defense | Click To Order
Fortifeye Macular Defense
Fortifeye™ Complete Macular Defense

Fortifeye™ Complete Macular Defense vitamins are the newest, most advanced nutraceuticals for your eyes and body, which provide purified Natural Triglyceride omega three fish oil, along with lutein and zeaxanthin for vision support. This formula provides the equivalent in antioxidant power to 15-17 servings of fruits and vegetables a day, 30 mg of lutein and 4.75 mg of zeaxanthin.

Dosage: 3 tablets + 1 softgel/day
30 Packs per box. Each daily pack contains 3 tablets and 1 softgel
Best price on the Internet! $70.00
Fortifeye Complete Macular Defense | Click To Order

 

 

All Fortifeye products are produced in a GMP, FDA and NNFA inspected facility that supplies products to the nutraceutical industry. Fortifeye is also approved by the Therapeutics Goods Association, the leading regulatory authority for nutraceuticals world wide and by NSF.

 

 

Fortifeye™ FOCUS

Fortifeye™ FOCUS is a combination of three carotenoids—astaxanthin, lutein and zeaxanthin. Clinical studies indicate that 6mg of astaxanthin reduces eye fatigue symptomology and actually improves amplitude of accommodation, the eye’s ability to focus clearly on objects at near distances. This new formulation was developed to help reduce accommodative stress due to prolonged working at a near focal length. Fortifeye FOCUS is recommended for individuals who experience eye fatigue with near point tasks or after prolonged work on a computer. Fortifeye FOCUS can be used alone or in combination with any of the Fortifeye™ Vitamins.

The Fortifeye™ Philosophy
Right Ingredients. Right Science. Right for You.

Fortifeye FOCUS

Fortifeye FOCUS is a powerful addition to the Fortifeye line of vitamins. Fortifeye FOCUS is a combination of three carotenoids – astaxanthin, lutein and zeaxanthin. This new formulation was developed to help reduce accommodative stress due to prolonged working at a near focal length. Fortifeye FOCUS is recommended for individuals who experience eye fatigue with near point tasks or after prolonged work on a computer. Clinical studies indicate that 6mg of astaxanthin reduces eye fatigue symptomology and actually improves amplitude of accommodation, the eye’s ability to focus clearly on objects at near distances. Many symptoms associated with eye fatigue including tired eyes, sore eyes and dry eyes were dramatically reduced in less than four weeks in clinical studies using 6mg of astaxanthin a day. Astaxanthin, a powerful antioxidant and anti-inflammatory, also helps to eliminate fine lines and wrinkles in the face, may help lower cholesterol, helps prevent sunburn to the skin and improves muscle endurance and muscle recovery in athletes. Studies also indicate astaxanthin may improve circulation and reduce inflammation in the eye. Fortifeye FOCUS is an exciting new nutritional approach to aid the millions of people suffering from eye fatigue while working with tasks at near focus. Fortifeye FOCUS can be used alone or in combination with any of the Fortifeye Vitamins.†

FortifeyeFOCUS

TIRED EYE RELIEF- rejuvenate, refresh and revive your eyes with AstaREAL® astaxanthin.†


Right Ingredients

    Fortifeye FOCUS is a combination of three carotenoids – astaxanthin, lutein and zeaxanthin.

    Astaxanthin – A relatively new nutrient used in supplements that comes from microalga Haematococcus pluvialis, astaxanthin is proving to have multiple health benefits. The carotenoid astaxanthin is the reason lobsters, shrimp and some crabs turn red when cooked. While it constitutes a tiny portion of farm-raised salmon feed (50 to 100 parts per million), astaxanthin represents up to 20 percent of the cost. Astaxanthin is an extremely potent antioxidant and anti-inflammatory. Clinical studies have now proven that 6mg of astaxanthin can improve the blood flow to the eye and actually aid in accommodation (focusing) and in reducing eye fatigue. It also helps to eliminate fine lines and wrinkles in the face, may help lower cholesterol, helps prevent sunburn to the skin and improves muscle endurance and muscle recovery in athletes. Astaxanthin reduces inflammatory markers such as nitric oxide synthase (NOS), prostaglandin E2 (PGE2) and tumor necrosis factor (TNF). Astaxanthin is documented with high potencies for neutralizing oxygen radicals. For example, it is 550 times more powerful than vitamin E or 40 times more powerful than beta-carotene against singlet oxygen radicals. These remarkable aspects of astaxanthin are why Fortifeye Vitamins has incorporated it into their new eye vitamin formulas.†

    Lutein – A carotenoid found naturally in dark green leafy vegetables (spinach and kale) and other natural sources, this potent antioxidant is sorely lacking in the typical American diet. Lutein and zeaxanthin are the only carotenoids found in the retina of the eye. Lutein supplementation has been shown in landmark clinical studies to increase macular pigment density which may promote macular health. Scientists believe lutein helps filter out dangerous ‘blue’ light, helping to maintain the photoreceptor and retinal health. Lutein is now believed to have a protective effect on the retina and may help to slow down age related macular degeneration. Lutein may have some protective effects against cataract formation.†

    Zeaxanthin – Zeaxanthin is one of the two carotenoids contained within the retina of the eye. Zeaxanthin and lutein have an almost identical chemical structure and have similar properties. Zeaxanthin, like lutein, increases macular pigment density and also helps to filter out the harmful blue light from the sun. Gogi berries have one of the highest sources of zeaxanthin and orange bell peppers are relatively high in zeaxanthin and more readily available. Zeaxanthin may also have some protective effects on cataract formation. Zeaxanthin may inhibit VEGF and prove useful for diabetic retinopathy and wet macular degeneration. Zeaxanthin and its related compound lutein are highly concentrated in the macula, providing a yellow color known as the macular pigment (MP). The macular pigment acts like a built in sun screen and protects the macula from the damaging photo-oxidative effects of blue light.†

    Dr. Lange has chosen AstaREAL® astaxanthin – The Astaxanthin of Choice. AstaREAL® astaxanthin is manufactured by Fuji Chemical Industry from Haematococcus pluvialis microalgae and is cultivated in ultra-clean BioDome™ systems in pristine Maui, Hawaii, and in state-of-the-art photobioreactors in environmentally friendly Gustavsberg, Sweden. AstaREAL® astaxanthin products are guaranteed for high potency, quality and stability. Fuji’s enclosed mass-culture systems generate the highest quality, purity and consistency of astaxanthin in the world.

    Fortifeye FOCUS can be used alone or in combination with any of the Fortifeye Vitamins.

 

In these videos Dr. Lange explains the many benefits of astaxanthin.

Dr Michael Lange discusses the benefits of astaxanthin, its sources, and the lack of astaxanthin in the diet. Benefits of astaxanthin in Fortifeye FOCUS, improve focusing ability, tired eye, reduce inflammation Dry eye syndrome, benefits of astaxanthin, omega-3 fish oil & gamma linolenic acid (GLA)


Right Science

    Clinical studies indicate that 6mg of astaxanthin reduces eye fatigue symptomology and actually improves amplitude of accommodation, the eye’s ability to focus clearly on objects at near distances.†

    Many symptoms associated with eye fatigue including tired eyes, sore eyes and dry eyes were dramatically reduced in less than four weeks in clinical studies using 6mg of astaxanthin a day.†

    Studies also indicate astaxanthin may improve circulation and reduce inflammation in the eye.†

View Astaxanthin Studies


Right For You

    Fortifeye FOCUS was developed for reviving, rejuvenating and refreshing tired eyes. It is used to help reduce eye fatigue and strain from prolonged near-work and computer work.†

    This new formulation was developed to help reduce accommodative stress due to prolonged working at a near focal length.†

    Fortifeye FOCUS is recommended for individuals who experience eye fatigue with near point tasks or after prolonged work on a computer.†

    Fortifeye FOCUS provides astaxanthin which in addition to benefiting the eyes helps to eliminate fine lines and wrinkles in the face, may help lower cholesterol, helps prevent sunburn to the skin and improves muscle endurance and muscle recovery in athletes.†

    Fortifeye FOCUS is an exciting new nutritional approach to aid the millions of people suffering from eye fatigue while working with tasks at near focus.†


†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Fortifeye FOCUS

Fortifeye FOCUS table of ingredients 

 

Lange Eye Care Locations

Gainesville Office
Lange Eye Care and Associates
3968 SW Archer Road W101
Gainesville, Florida 32608
Phone: 352-376-6622

Ocala Office
Lange Eye Care and Associates
3101 SW College Road
Ocala, Florida 34474
Phone: 352-237-3768

Triple Crown Plaza Office
Lange Eye Care and Associates
11100 SW 93rd Court Road
Suite 15
Ocala, Florida 34481
Phone: 352-291-2000

Summerfield Office
Lange Eye Care Vision Outlet Center
Unit #604 Highway 441S
Summerfield, Florida
Phone: 352-307-3273

Inverness Office
Lange Eye Care and Associates
3808 E. Gulf to Lake Highway
Inverness, FL 34453
Phone: 352-344-5110

Clearwater Offices
Lange Eye Care Optical Gallery & LASIK Center
23666 U. S. Highway 19 North
Clearwater, FL 33765
Phone: 727-791-1214

Lange Sun and Nutrition Center
2551 Drew Street
Suite 302
Clearwater, FL 33765
Phone: 727-216-6275

Williston Office
Lange Eye Care And Associates
129 S. W. 7th Street
Williston, FL 32696
Phone: 352-528-0433

The Villages Office
Lange Eye Institute
466 and CR101
The Villages, Florida
Phone: 352-753-4014

 

 

 

 

Map and Directions


View Larger Map

 

More information: Dr. Michael P. Lange is a Board Certified Optometric Physician and a Certified Nutrition Specialist who started Lange Eye Care and Associates in Ocala, Florida, in March 1993. Lange Eye Care has grown to nine locations throughout the state of Florida with three Lasik centers. The Lange Eye Institute at The Villages in central Florida is home base for many of the nutritional studies that Fortifeye is involved in. Dr. Lange is one of the first doctors in the industry to utilize intracellular blood tests and blood absorption studies to improve the Fortifeye vitamin line. Dr. Lange travels the world for nutritional research gathering valuable information to continuously improve Fortifeye vitamin formulations. Dr. Lange is still involved in the clinical practice of eyecare. He is a guest lecturer, contributing author to many eyecare magazines, and a daily syndicated talk show host of ‘Ask The Doctor’ which broadcasts every weekday at 9am and Saturdays at 2pm from Tampa Bay on radio stations throughout the country and video streaming all over the world via the Internet.

 

 

 

 

Order Fortifeye™ vitamins by clicking below:

 

Fortifeye Complete Plus | Click To Order
Fortifeye Complete Plus | Click To Order
Fortifeye™ Complete Plus

Fortifeye™ Complete Plus is an advanced formulation based on the latest clinical studies. It is a combination of synergistically blended whole foods, phytonutients, vitamins, minerals, enzymes and essential fatty acids. When combined with proper diet, exercise and a healthy life style Fortifeye™ Complete Plus lays the foundation for good eye and total body health.

Dosage: 2 tablets + 1 softgel/day
30 Packs per box. Each daily pack contains 2 tablets and 1 softgel
Best price on the Internet! $50.00
Fortifeye Complete Plus | Click To Order

Fortifeye Super Omega-3 Fish Oil | Click To Order
Fortifeye Super Omega-3 Fish Oil
Fortifeye™ Super Omega 3 Fish Oil

Fortifeye™ Super Omega-3 Fish Oil is the newest, most concentrated and purified Omega Three Fish Oil by Fortifeye™
Features: Natural Triglyceride Form • Molecularly Distilled for Maximum Purity • High Potency/Triple Strength • Natural Orange/ Lemon Flavor • Pharmaceutical Grade • Superior taste • No unpleasant odor • Unsurpassed purity (Triple Molecular distillation) • Produced in Norway in the world’s only NSF, GMP certified Omega 3 production facility
Promotes: Heart Health • Brain Health • Eye Health • Joint Health • Circulation • Good Blood Pressure • Healthy Cholesterol • Improved Triglycerides • Skin, Hair & Nail Health • Mental & Cognitive Health

Take Fortifeye™ Super Omega-3 in conjunction with Fortifeye™ Complete Plus for more intensive nutritional therapy.

Dosage: 2 softgels/day
60 softgels/bottle
Best price on the Internet! $25.00
Fortifeye Super Omega-3 Fish Oil | Click To Order

Fortifeye FOCUS | Click To Order
Fortifeye FOCUS | Click To Order
Fortifeye™ FOCUS

Fortifeye™ FOCUS is a combination of three carotenoids—astaxanthin, lutein and zeaxanthin. Clinical studies indicate that 6mg of astaxanthin reduces eye fatigue symptomology and actually improves amplitude of accommodation, the eye’s ability to focus clearly on objects at near distances. This new formulation was developed to help reduce accommodative stress due to prolonged working at a near focal length. Fortifeye FOCUS is recommended for individuals who experience eye fatigue with near point tasks or after prolonged work on a computer. Fortifeye FOCUS can be used alone or in combination with any of the Fortifeye™ Vitamins.

Dosage: 1 softgel per day
30 softgels per bottle.
Best price on the Internet! $25.00
Fortifeye FOCUS | Click To Order

Fortifeye Complete One-A-Day | Click To Order
Fortifeye Complete One-A-Day | Click To Order
Fortifeye™ Complete
One-A-Day Multivitamin

Fortifeye™ Complete One-A-Day is a powerhouse combination of 50 total body and vision specific nutrients all combined into one USP certified tablet. Fortifeye™ Complete One-A-Day multivitamin has been created by doctors who understand that quality counts. Fortifeye™ Complete One-A-Day can be used alone or in combination with Fortifeye™ Super Omega 3 Fish Oil or Fortifeye™ Dry Eye Therapy Extreme to combat against free radical damage in the eyes and body.

Dosage: 1 tablet per day
30 tablets per bottle.
Best price on the Internet! $25.00
Fortifeye Complete One-A-Day | Click To Order

Fortifeye Complete Macular Defense | Click To Order
Fortifeye Macular Defense
Fortifeye™ Complete Macular Defense

Fortifeye™ Complete Macular Defense vitamins are the newest, most advanced nutraceuticals for your eyes and body, which provide purified Natural Triglyceride omega three fish oil, along with lutein and zeaxanthin for vision support. This formula provides the equivalent in antioxidant power to 15-17 servings of fruits and vegetables a day, 30 mg of lutein and 4.75 mg of zeaxanthin.

Dosage: 3 tablets + 1 softgel/day
30 Packs per box. Each daily pack contains 3 tablets and 1 softgel
Best price on the Internet! $70.00
Fortifeye Complete Macular Defense | Click To Order

 

 

All Fortifeye products are produced in a GMP, FDA and NNFA inspected facility that supplies products to the nutraceutical industry. Fortifeye is also approved by the Therapeutics Goods Association, the leading regulatory authority for nutraceuticals world wide and by NSF.

 

 

A New Generation One-A-Day Multivitamin Supplement

An incredible new one-a-day multivitamin supplement for eyes and body, Fortifeye vitamins offers the best vitamin supplements for free radical damage, macular degeneration and proper nutrition. Get a good multivitamin supplement with grape seed extract, lutein, zeaxanthin, vitamins and minerals. Fortifeye One A Day Multivitamin health supplements contain no vitamin A or beta carotene.

The Incredible New One-A-Day Multivitamin Supplement by Fortifeye Vitamins

Total Body Health and Vision Support in One Tablet a Day

 

Are vitamin supplements as beneficial as claimed in some of today’s advertising? Can a one-a-day multivitamin really contain the vitamins and minerals necessary to promote wellness?

Nutrition supplements have become the latest rage in America due to the positive spin the health and wellness experts have promoted thru the media. Health supplements and diet supplements are being marketed on infomercials all over television, radio and the Internet with incredible deals to promote the sale of these vitamin supplements. Everyone is claiming to have the best vitamin or best supplement, so who should you believe?

Half face imageWe all want to live a long, healthy and prosperous life, however many of us fall short of reaching our lifetime goals because of poor health. Proper nutrition is one of the most important single factors in maintaining our health. Most people in today’s society are not getting the required vitamins and minerals from the foods they are eating. We have become a society living ‘life on the go’ that is fueled by fast food and junk food. Our typical diet is caloric dense and nutrient deficient. Americans consume a diet that is unbalanced—with too many omega-6 fatty acids and not enough omega-3 fatty acids—leading to increased inflammation and disease in the body. Our foods are processed, sugar- and salt-laden, filled with trans fats, hydrogenated oils, high fructose corn syrup, synthetic dyes and artificial sweeteners. These poor nutritional habits combined with a sedimentary lifestyle are why the health of the American people is becoming compromised. America is home to the most obese people in the world. According to the CDC (Center for Disease Control and Prevention) obesity in adults has increased by 60% within the past twenty years and obesity in children has tripled in the past thirty years. A staggering 70% of American adults are overweight or obese and obesity related deaths have accelerated to more than 300,000 a year, second only to tobacco related deaths.

How high an ORAC (oxygen radical absorbency capacity) is your multivitamin?

Antioxidants fruits and vegetablesMost nutritional experts recommend 6-13 servings of fruits and vegetables a day. Americans are falling short of this amount and are becoming more and more nutritionally compromised. 80% of American children and almost 70% of adults are not even consuming five portions of fruits and vegetables a day. The population that consumes the least amount of vegetables and fruits are more predisposed in developing disease and illness. These large and growing groups of people are nutritionally compromised and more prone to develop free radical damage in their bodies and eyes. Can a one-a-day multivitamin really help with these nutrition deficiencies? Many people are misled into believing they can go to the local drug store or warehouse club and purchase a multivitamin supplement that will counteract the poor diets they are on. Many of the health supplements and multivitamins that are sold at the local drug store or commercial warehouse clubs are filled with red, yellow and blue dyes, synthetic nutrients and trans fats—all of the things that are bad for you!

Many of the multivitamins and health supplements have only ‘window dressing’ amounts of specific nutrients, not enough to even register in your blood. These supplements oftentimes have minimal antioxidant power and yet they ‘sell like hot cakes’ due to aggressive advertising and promotions. Many of these vitamins are not USP certified and may not have any absorption value at all! Studies done at Jean Mayer USDA Human Research Center on Aging at Tufts University suggest that consuming fruits and vegetables with a high ORAC (oxygen radical absorbency capacity) value may help slow down the aging process in the body and brain. Studies have also indicated that taking a vitamin supplement with a high ORAC value may also improve antioxidant status in the human body. However, most of the typical one-a-day multivitamin supplements you purchase over the counter have an ORAC value of less than 100. These types of multivitamins are not very useful at combating against free radical damage. Remember—“you get what you pay for”.

Best vitamin supplements to combat free radical damage

Right Ingredients, Right Science, Right For You.Fortifeye Vitamins is embracing the latest science on free radical damage, antioxidant therapy and ORAC research in the continuous development of their vitamin supplements. Fortifeye is using this science combined with intracellular blood tests to maximize cellular absorption of each Fortifeye product. After six years of research and development Fortifeye has released their newest multivitamin supplement called Fortifeye Complete One-A-Day Multivitamin. This is a nutraceutical (vitamin and mineral) formula taken once a day that has an ORAC value of approximately 4250 per serving in each tablet. This is equivalent in antioxidant power to approximately five or six servings of fruits and vegetables a day. Fortifeye’s goal was to develop a multivitamin that was made to support total body and vision health that was convenient, affordable and based on the latest research. Fortifeye Complete One-A-Day Multivitamin is all natural without any synthetic nutrients, dyes, trans fats or artificial sweeteners. Fortifeye Complete One-A-Day Multivitamin is great for anyone that wants to insure that they are getting enough antioxidants during the day to combat against free radical damage and aid in the total health of their body and eyes.

High bioavailability and packed with powerful antioxidants

Fortifeye Complete One-A-Day box imageFortifeye has taken a powerhouse combination of 50 total body and vision specific nutrients and combined them all into one USP certified tablet. Fortifeye Complete One-A-Day Multivitamin has been created by doctors who understand that quality counts. Each nutrient was chosen based on the highest manufacturing standards and metabolic uptake ability by the body (called bioavailability). This formula was created to minimize nutritional deficiencies and maximize the total antioxidant function at a cellular level. Some newly researched nutrients like resveratrol, green tea, soy isoflavones, curcumin, rutin, zeaxanthin, tocotrienols, vitamin B and vitamin D along with the ‘super berries’ have been added to this formula to gain some of the exciting health benefits. These nutrients are powerful antioxidants that may also help inhibit the formation of “bad” blood vessels (anti-VEGF, which means anti-vascular endothelial growth factor) and are considered natural anti-inflammatory agents. These specific nutrients are being studied for their potential benefits in cancer, arthritis, diabetes, cholesterol, heart disease, eye diseases and as neuroprotectants. Many studies now suggest that increasing intake of dark green leafy vegetables and darkly pigmented berries may also benefit macular degeneration and overall health. Kale, spinach and blueberries along with bilberries and grape seed extract have been included in the Fortifeye Complete One-A-Day Multivitamin formula. In addition, 10 mg of lutein and 1.575 mg of zeaxanthin have been added to help replenish the macula pigment density, filter out the dangerous blue light and also act as a powerful antioxidant to neutralize free radicals in the eye and body.

Macular degeneration and proper nutrition

Current science indicates that macula density in the retina progressively decreases as macular degeneration progresses. Lutein and zeaxanthin are proving to be beneficial for both macular degeneration and cataracts. The total antioxidant value (ORAC value) of Fortifeye Complete One-A-Day Multivitamin is one of the highest available in the industry for one tablet at 4,250. This is equivalent to approximately 6 servings of fruits and vegetables a day. Super foods like gogi, acai, mangosteen, blueberry, grape seed extract, pomegranate, cinnamon and cocoa were blended to increase the ORAC to these levels. Acetyl-L-carnitine, alpha lipoic acid and CoQ-10 were introduced to support mitochondria health and aid in neuroprotection. All eight forms of vitamin E (four tocopherols and four tocotrienols) are utilized in this formula to maximize free radical quenching. The most absorbable form of zinc called Opti Zinc is used to increase bioavailability. Vitamin A deficiencies are very rare in developed countries—and too much does pose some serious health risks—so no vitamin A is found in the Fortifeye Complete One-A-Day Multivitamin formula. Beta carotene has been linked to lung cancer in smokers and studies now indicate that beta carotene may block the absorption of lutein, so no beta carotene is found any of the Fortifeye products. Many other nutrients are used in this comprehensive one-a-day formula in precise ratios to aid in maximum cellular absorption.

Fortifeye Complete One-A-Day Multivitamin can be used alone or in combination with Fortifeye Super Omega or Fortifeye Dry Eye Therapy Extreme to combat against free radical damage in the eyes and body.

Take advantage of the latest research

Choose the best multivitamin supplement for your eyes and whole body

When Fortifeye vitamins are combined with lifestyle changes and dietary modifications significant improvements in the health of the eyes and body can be achieved. Fortifeye Complete One-A-Day Multivitamin is recommended to anyone wanting to become proactive in their future health. If you are like most Americans you are not getting the required amounts of proper nutrition through your current diet. It is time that you become proactive in your health and consider taking a good multivitamin supplement. Do your own research and compare what Fortifeye Complete One-A-day has to offer as compared to what is available at the stores. See the Supplement Facts at the bottom of this page. If you are looking for a great multivitamin that is truly based on legitimate science and is actively being studied and constantly being enhanced, then Fortifeye Complete One-A-Day multivitamin may be for you.

Fortifeye Super Omega-3 Fish Oil box imageFor best results, also take a triglyceride based omega three fish oil

Go to www.fortifeye.com and see the many benefits Fortifeye vitamins have to offer. I do highly recommend everyone who takes a good multivitamin to also take a good triglyceride based omega three fish oil supplement. Fortifeye Super Omega, pictured to the right, is one of the most concentrated and purest omega three fish oils available. The combination of Fortifeye Complete One-A-Day and Fortifeye Super Omega may help improve your quality of life through proper nutrition.

Michael P. Lange, O.D.
Dr. Michael P. Lange
Board Certified Optometric Physician and Board Certified Nutritional Specialist

 

 

Dr. Michael P. Lange
Board Certified Optometric Physician
Certified Nutrition Specialist
Syndicated Daily Talk Show Host (Ask the Doctor)
www.langeeyecare.com
www.fortifeye.com
May 2, 2010

 

Author: Dr. Michael P. Lange is a Board Certified Optometric Physician and a Certified Nutrition Specialist who started Lange Eye Care and Associates in Ocala, Florida, in March 1993. Lange Eye Care has grown to nine locations throughout the state of Florida with three Lasik centers. The Lange Eye Institute at The Villages in central Florida is home base for many of the nutritional studies that inspired the Fortifeye Brand of vitamin supplements. Dr. Lange is one of the first doctors in the industry to utilize intracellular blood tests and blood absorption studies to improve the Fortifeye vitamin line. Dr. Lange travels the world for nutritional research gathering valuable information to continuously improve Fortifeye vitamin formulations. Dr. Lange is still involved in the clinical practice of eyecare. He is a guest lecturer, contributing author to many eyecare magazines, and a daily syndicated talk show host of ‘Ask The Doctor’ which broadcasts every weekday at 9 a.m. and Saturdays at 2 p.m. from Tampa Bay on radio stations throughout the country and video streaming all over the world via the Internet. Detailed information on the nutritional research Dr. Lange has been involved in, and the eye vitamins and whole body formulas he has formulated, are at www.Fortifeye.com. If you are looking for a great group of eye doctors in Florida go to www.LangeEyeCare.com. For more, read this article about Dr. Michael Lange, Ocala optometrist involved in research on nutrition and UV protection, or read this biography of Dr. Michael Lange, Ocala eye doctor (optometrist).

One-A-Day Supplement Facts

Lange Eye Care Locations

Gainesville Office
Lange Eye Care and Associates
3968 SW Archer Road W101
Gainesville, Florida 32608
Phone: 352-376-6622

Ocala Office
Lange Eye Care and Associates
3101 SW College Road
Ocala, Florida 34474
Phone: 352-237-3768

Triple Crown Plaza Office
Lange Eye Care and Associates
11100 SW 93rd Court Road
Suite 15
Ocala, Florida 34481
Phone: 352-291-2000

Summerfield Office
Lange Eye Care Vision Outlet Center
Unit #604 Highway 441S
Summerfield, Florida
Phone: 352-307-3273

Inverness Office
Lange Eye Care and Associates
3808 E. Gulf to Lake Highway
Inverness, FL 34453
Phone: 352-344-5110

Clearwater Offices
Lange Eye Care Optical Gallery & LASIK Center
23666 U. S. Highway 19 North
Clearwater, FL 33765
Phone: 727-791-1214

Lange Sun and Nutrition Center
2551 Drew Street
Suite 302
Clearwater, FL 33765
Phone: 727-216-6275

Williston Office
Lange Eye Care And Associates
129 S. W. 7th Street
Williston, FL 32696
Phone: 352-528-0433

The Villages Office
Lange Eye Institute
466 and CR101
The Villages, Florida
Phone: 352-753-4014

 

 

 

 

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More information: Dr. Michael P. Lange is a Board Certified Optometric Physician and a Certified Nutrition Specialist who started Lange Eye Care and Associates in Ocala, Florida, in March 1993. Lange Eye Care has grown to nine locations throughout the state of Florida with three Lasik centers. The Lange Eye Institute at The Villages in central Florida is home base for many of the nutritional studies that Fortifeye is involved in. Dr. Lange is one of the first doctors in the industry to utilize intracellular blood tests and blood absorption studies to improve the Fortifeye vitamin line. Dr. Lange travels the world for nutritional research gathering valuable information to continuously improve Fortifeye vitamin formulations. Dr. Lange is still involved in the clinical practice of eyecare. He is a guest lecturer, contributing author to many eyecare magazines, and a daily syndicated talk show host of ‘Ask The Doctor’ which broadcasts every weekday at 9am and Saturdays at 2pm from Tampa Bay on radio stations throughout the country and video streaming all over the world via the Internet.

 

 

 

Order Fortifeye™ vitamins by clicking below:

 

Fortifeye Complete Plus | Click To Order
Fortifeye Complete Plus | Click To Order
Fortifeye™ Complete Plus

Fortifeye™ Complete Plus is an advanced formulation based on the latest clinical studies. It is a combination of synergistically blended whole foods, phytonutients, vitamins, minerals, enzymes and essential fatty acids. When combined with proper diet, exercise and a healthy life style Fortifeye™ Complete Plus lays the foundation for good eye and total body health.

Dosage: 2 tablets + 1 softgel/day
30 Packs per box. Each daily pack contains 2 tablets and 1 softgel
Best price on the Internet! $50.00
Fortifeye Complete Plus | Click To Order

Fortifeye Super Omega-3 Fish Oil | Click To Order
Fortifeye Super Omega-3 Fish Oil
Fortifeye™ Super Omega 3 Fish Oil

Fortifeye™ Super Omega-3 Fish Oil is the newest, most concentrated and purified Omega Three Fish Oil by Fortifeye™
Features: Natural Triglyceride Form • Molecularly Distilled for Maximum Purity • High Potency/Triple Strength • Natural Orange/ Lemon Flavor • Pharmaceutical Grade • Superior taste • No unpleasant odor • Unsurpassed purity (Triple Molecular distillation) • Produced in Norway in the world’s only NSF, GMP certified Omega 3 production facility
Promotes: Heart Health • Brain Health • Eye Health • Joint Health • Circulation • Good Blood Pressure • Healthy Cholesterol • Improved Triglycerides • Skin, Hair & Nail Health • Mental & Cognitive Health

Take Fortifeye™ Super Omega-3 in conjunction with Fortifeye™ Complete Plus for more intensive nutritional therapy.

Dosage: 2 softgels/day
60 softgels/bottle
Best price on the Internet! $25.00
Fortifeye Super Omega-3 Fish Oil | Click To Order

Fortifeye FOCUS | Click To Order
Fortifeye FOCUS | Click To Order
Fortifeye™ FOCUS

Fortifeye™ FOCUS is a combination of three carotenoids—astaxanthin, lutein and zeaxanthin. Clinical studies indicate that 6mg of astaxanthin reduces eye fatigue symptomology and actually improves amplitude of accommodation, the eye’s ability to focus clearly on objects at near distances. This new formulation was developed to help reduce accommodative stress due to prolonged working at a near focal length. Fortifeye FOCUS is recommended for individuals who experience eye fatigue with near point tasks or after prolonged work on a computer. Fortifeye FOCUS can be used alone or in combination with any of the Fortifeye™ Vitamins.

Dosage: 1 softgel per day
30 softgels per bottle.
Best price on the Internet! $25.00
Fortifeye FOCUS | Click To Order

Fortifeye Complete One-A-Day | Click To Order
Fortifeye Complete One-A-Day | Click To Order
Fortifeye™ Complete
One-A-Day Multivitamin

Fortifeye™ Complete One-A-Day is a powerhouse combination of 50 total body and vision specific nutrients all combined into one USP certified tablet. Fortifeye™ Complete One-A-Day multivitamin has been created by doctors who understand that quality counts. Fortifeye™ Complete One-A-Day can be used alone or in combination with Fortifeye™ Super Omega 3 Fish Oil or Fortifeye™ Dry Eye Therapy Extreme to combat against free radical damage in the eyes and body.

Dosage: 1 tablet per day
30 tablets per bottle.
Best price on the Internet! $25.00
Fortifeye Complete One-A-Day | Click To Order

Fortifeye Complete Macular Defense | Click To Order
Fortifeye Macular Defense
Fortifeye™ Complete Macular Defense

Fortifeye™ Complete Macular Defense vitamins are the newest, most advanced nutraceuticals for your eyes and body, which provide purified Natural Triglyceride omega three fish oil, along with lutein and zeaxanthin for vision support. This formula provides the equivalent in antioxidant power to 15-17 servings of fruits and vegetables a day, 30 mg of lutein and 4.75 mg of zeaxanthin.

Dosage: 3 tablets + 1 softgel/day
30 Packs per box. Each daily pack contains 3 tablets and 1 softgel
Best price on the Internet! $70.00
Fortifeye Complete Macular Defense | Click To Order

 

 

All Fortifeye products are produced in a GMP, FDA and NNFA inspected facility that supplies products to the nutraceutical industry. Fortifeye is also approved by the Therapeutics Goods Association, the leading regulatory authority for nutraceuticals world wide and by NSF.

 

 

Changes in Diet, Vitamins and Lifestyle Modifications To Help Macular Degeneration

How Can Changes in Diet, Vitamins and Lifestyle Modifications Help Macular Degeneration?
Vitamin therapy and lifestyle modifications have proven to be extremely valuable at helping to stabilize Macular Degeneration.

Dr, Michael P. Lange, Board Certified Optometric Physician
and Board Certified Nutritional Specialist
Lange Eye Care and Associates / Lange Eye Institute
12/27/2009

Macular Degeneration is the leading cause of vision impairment for people over the age of 55 in the United States.

Fortifeye Complete Macular Defense pillMacular Degeneration is the leading cause of legal blindness in the United States in the over 55 age group. Currently there are close to two million people living in our country that are vision impaired from macular degeneration. With our population living longer and longer it is estimated that over 3 million people by 2020 will have Age Related Macular Degeneration (ARMD). By then each of us will know someone that has lost their vision from macular degeneration. Macular degeneration is a medical condition that causes degeneration of the central part of the retina called the macula.

There are two basic types of Age Related Macular Degeneration:
1. Wet ARMD or neovascular ARMD, which means abnormal growth of new blood vessels which grow into the retina and leak causing edema and atrophy of the central retina.
2. Dry ARMD or non-neovascular ARMD. The dry form of macular degeneration is the most common type with around 85%-90% of sufferers having the dry form.

The wet form of macular degeneration is the most destructive and the onset can be fairly rapid. The dry form of ARMD can slowly steal a patients central vision until they become legally blind. Optometrists and Ophthalmologists work on new therapiesAn estimate of about 20% of dry ARMD can turn into wet ARMD. Some people may have an increased risk of developing macular degeneration because of their genetic makeup. However, most cases of macular degeneration are probably related to a combination of genetics, poor nutrition, sedimentary lifestyle and environmental factors. Significant research in the area of macular degeneration looks very promising. The evolving therapies the Board Certified Optometrists and Ophthalmologists have developed bring new hope for anyone diagnosed with ARMD. These new therapies may halt, improve or even cure forms of macular degeneration. Ongoing research in macular degeneration is constantly revealing new ways to help the macular degenerative patient and maintains a very high level of hope for the future care of ARMD. Ultimately we look forward to a future where macular degeneration no longer poses a threat to vision.

What can be done to decrease the risk of going blind from Macular Degeneration?

Keeping an eye on Macular DegenerationNutritional intervention and lifestyle modifications may be beneficial at helping to stabilize macular degeneration. I have personally seen thousands of patients with macular degeneration in clinical practice for over 18 years. I have seen the positive benefits that patients can realistically obtain thru nutritional intervention and lifestyle modifications. Many patients with macular degeneration are benefiting dramatically from visiting an eye care provider that is in tune with the latest in nutritional therapy. Doctors from all over the world are using dietary modifications, introduction of nutraceuticals and lifestyle changes to aid the patient with macular degeneration. These doctors have seen some incredible improvements in vision as well as overall health in these patients. Optometrists and ophthalmologists often times utilize intracellular and plasma blood testing along with advanced retinal imaging to help determine if a patient may have modifiable risk factors for macular degeneration. Some of these modifiable risk factors include elevated c-reactive protein, elevated cholesterol, elevated triglycerides, elevated homocysteine, lipofuscin pigment accumulation and nutritional deficiencies. The following is a list of 17 steps that can be utilized to decrease the risk of having progressive visual loss from macular degeneration. This list was compiled based on solid scientific evidence reported in related literature and from positive results we have seen clinically in several very large macular degeneration practices. This does not replace a comprehensive dilated eye examination by a board certified optometrist or ophthalmologist.

1. Eat wild Alaskan salmon for healthFollow a low fat diet. Decrease saturated fats and trans fatty acids. Eat more turkey, chicken , cold water fish and soy products like Garden Burgers (a popular vegetarian meat substitute), soy milk and tofu. Eat less corn fed beef, whole milk and cheese. Eat the breast meat of chicken and turkey from free roaming organically raised sources (if possible), and prepare without deep frying. Broiling, grilling, boiling or baking is healthier. Eat more fish (omega-3) but be careful when eating fish because many large fish have toxic levels of mercury, lead and PCBs (PCBs are persistent organic pollutants, banned since 1977, that entered the environment through both original use and later disposal). Eat cold water fish (sardines, tuna, mackerel, lake trout, Atlantic halibut, herring and wild—not farmed—salmon). Try to avoid farm raised fish and instead eat wild fish especially wild Alaskan salmon. Wild salmon are high in a super carotenoid called astaxanthin that is proving to be a key nutrient in the nutritional approach for macular degeneration. A lean organically raised GRASS FED steak in moderation is a good source of protein, Vitamin B complex, zinc, iron, folate, magnesium, selenium and omega-3 essential fatty acids. A good source of grass fed organic beef is www.grassisgood.com. Omega-6 fats predominate in commercially-raised (corn-fed) meat, poultry, dairy and eggs; and also in nuts, seeds, margarine, and vegetable oils (such as corn, peanut, canola, safflower, soybean, sunflower, and grape seed oils). Omega-6 increases inflammation in the body! Olive oil is an omega-9 and is beneficial; it should be the primary bottled oil in the kitchen for use in cooking and salad dressings. The typical American diet provides 10-20 times more omega-6 than omega-3, but a healthier ratio is 3:1 or 4:1! Cut back on your omega-6 (choosing healthy omega-6 foods like nuts, seeds, and avocado) and increase omega-3.

2. Spinach is a dark green leafy vegetableConsume more dark green leafy vegetables like spinach, kale, collards and swiss chard (preferably organically grown). Carefully boil, steam or simmer these in extra virgin olive oil. Gentle cooking helps to break down the cell wall releasing the bio-availability of the greens. Juicing is also a good way of getting these nutrients. Lutein is abundant in dark green leafy vegetables and has been shown to potentially help slow down the devastating properties of macular degeneration. Lutein and its related compound zeaxanthin are highly concentrated in the macula, providing a yellow color known as the macular pigment (MP).The macular pigment acts like a built in sun screen and protects the macula from the damaging photo-oxidative effects of blue light. Eating more foods that contain lutein and/or taking a supplement with 10-30 mg of lutein daily will help replenish the macula pigment density that you are more prone to loose as you age with macular degeneration. If you are taking a blood thinner like Coumadin, consult with your physician prior to eating more dark green leafy vegetables.

3. Orange bell peppers are high in zeaxanthinEat more orange bell peppers (preferably organically grown), gently cooked or raw. Orange bell peppers are very high in zeaxanthin. Scientists believe this nutrient when combined with lutein helps filter out dangerous HEV light (blue light) and may help maintain macular health. Sauté spinach and orange bell peppers together in extra virgin olive oil for good macular health. Goji berries are also one of nature’s most powerful antioxidants that has a very high concentration of zeaxanthin. Goji berry is one of the richest edible plant sources known for zeaxanthin content. Up to 77% of total carotenoids present in goji berry exist as zeaxanthin. Both goji berry and zeaxanthin also may prove to be helpful in the irregular blood vessel growth and leakage that occurs in the wet form of macular degeneration due to their potential anti-VEGF properties.

4. Blackberries for macular functioningConsume more darkly pigmented berries (preferably organically grown). Studies indicate that eating more dark berries like blueberries, black berries and raspberries may help preserve macular health. Some of the “super fruits” like gogi berry, acai berry and mangosteen are powerful antioxidants that may prove to be beneficial for macular disease. These are not easily found in your local grocery unless they are in a juice or powdered form. If you are a diabetic consult with your physician prior to eating more fruits. Darkly pigmented berries may also exhibit some anti-VEGF attributes.

5. Get more omega 3 fatty acids by taking micro distilled triglyceride fish oil. Stay away from the ethyl ester form of fish oil due to alcohol being attached to the molecule and poorer absorption rate when compared to triglyceride fish oil. Fortifeye Super Omega-3 Fish Oil | Click To OrderDue to the large amount of pollutants in fish, molecularly distilled triglyceride fish oil may be a better option than eating the fish. Canned sardines are a good source of omega threes, protein, Co-Q10 and calcium, and are fairly contaminant free. Eat more cold-water fish (sardines, tuna, mackerel, lake trout, Atlantic halibut, herring and wild—not farmed—salmon). Flax seed oil is not a good source of omega-3 essential fatty acids! I recommend Fortifeye Super Omega since it is the more natural concentrated triglyceride form of omega-3 and goes through a triple molecular distillation process to insure it is contaminant free. This gel cap is also chewable with a great taste for those patients that have difficulty swallowing pills. Fortifeye Vitamins phone number is 1-866-503-9746 or go to www.fortifeye.com.

6. Eat less salt. Research may indicate that decreasing salt intake may decrease deposition of waste products in the macula called drusen. Reduction in salt intake may help decrease blood pressure and fluid retention.

7. Wear blue blocking sunglasses especially if you have had cataract surgery. There is science that indicates blocking the high energy visible spectrum (400nm-500nm, the “blue light”), may help prevent damage to the macula. Yellow, amber and orange colored lenses are good at blocking the blue light. Wear them any time you are outdoors during daylight. Wear polarized blue blockers while in the sun. Non-polarized lenses are better while indoors, during cloudy and overcast days and for certain sports like motorcycling, golf, road biking and mountain biking.

8. No smoking!NO SMOKING! If you do smoke try to quit. Smoking lowers your serum antioxidant levels in your blood and thus causes a nutritional deficiency at the cellular level. Second hand smoke is just as bad. Smokers increase their risk dramatically of developing the more advanced stages of macular degeneration. Smoking increases C-reactive protein (inflammatory marker in blood that is a risk factor for macular degeneration). If you smoke be sure you do NOT take high levels of the supplement called beta-carotene. High dosages of beta-carotene my increase ones risk of lung cancer. New science also indicates beta-carotene may interfere with the absorption of lutein (a beneficial carotenoid for macular health). Beta-carotene should not be in a vitamin formula especially if you have macular degeneration. Vegans may want to supplement with beta-carotene since they arent getting any vitamin A from animal sources, however most Americans that do eat some animal protein will not be deficient in Vitamin A and thus dont need any beta-carotene. Beta-carotene has shown some form of competitive inhibition against lutein that may begin in the stomach.

9. Do cardiovascular exercises for 20-30 minutes 5 times a week (discuss this with your physician first). Research indicates that patients who did cardiovascular exercise (treadmill, stationary bike, elliptical, walking, jogging, swimming etc.) were less likely to develop macular degeneration. These forms of exercise may be beneficial for glaucoma patients as well.

10. If you are overweight, LOSE WEIGHT! Overweight people are twice as likely to develop macular degeneration. Losing weight will also reduce C-reactive protein and help to normalize cholesterol and triglycerides. Controlling C-reactive, cholesterol and triglycerides may benefit macular degeneration. Overweight patients are also more likely to develop glaucoma and cataracts at an earlier age. Reducing your caloric intake and increasing your cardiovascular exercise will aid in weight reduction. Patients who are over weight with pre-existing health conditions may want to seek help from a physician supervised weight loss program.

11. Control systemic health problems such as hypertension, diabetes, elevated C-reactive protein and elevated homocysteine. Elevated homocysteine has been linked to macular degeneration as well as optic neuropathies, certain types of glaucoma, retinal occlusive disease and diabetic retinopathy. Patients who are overweight can have a dramatic improvement in these systemic health problems once they start a weight management program and stick to it.

Choose red wine for eye health12. Drink red wine and green tea! New research may indicate that drinking red wine in moderation, sipping green tea, eating more soy products and cooking with curry may have some positive impact on macular degeneration, cataracts and inflammatory diseases in the eye. Consume more Pinot Noir from the New York region, because this wine has some of the highest resveratrol content. Resveratrol is a powerful antioxidant proving to have many health benefits. Walnuts are also a good source of resveratrol. The latest research shows that soy, resveratrol, green tea and curcumin may all have the ability to inhibit new fragile blood vessel growth (anti VEG-F). This may prove to be beneficial at decreasing the chance of the dry form of macular degeneration from turning into the wet form. Some other specific nutrients that may also exhibit effects on VEGF are Vitamin D, rutin, zeaxanthin, tocotrienols, super berries and even B vitamins.

Macular Degeneration sufferer13. Have a vitamin D blood test; 25 (OH) D done routinely, making sure you are not deficient in Vitamin D. Recent research shows patients with low levels of serum Vitamin D may be more likely to develop macular degeneration. Vitamin D is a potent steroid hormone and deficiencies are linked to cancer, cardiovascular disease, stroke, hypertension, diabetes, osteoathritis, osteoporosis, depression, multiple sclerosis, muscle wasting, schizophrenia and even the flu. The sun is the best source of Vitamin D. Just 15-20 minutes of sun exposure during the peak hours in shorts and a tank top while wearing a good pair of blue blocking sunglasses and a wide brimmed hat may be beneficial. Consult with your physician before too much sun exposure especially if there is a history of skin cancers or melanoma.

14. Dark Chocolate is high in polyphenols and antioxidants that may prove to be beneficial for macular degeneration. The darker the chocolate the better. Dark chocolate is proving to be good for for many health conditions including diabetes, hypertension, and elevated cholesterol and may reduce the risk of blood clots, strokes and heart attacks. Polyphenols from dark chocolate may also exhibit some anti-VEGF properties and may prove to be beneficial for macular degeneration. Try to eat the dark chocolate with the highest percent of cocoa and the least amount of sugar.

15. Do not take supplemental beta-carotene! Many emerging studies are proving that supplemental beta-carotene blocks the absorption of lutein. Beta-carotene also increases the risk of lung cancer among smokers. There is no beta-carotene in the eye, however, there is a high percent of lutein concentrated in the macula, so macular degeneration patients do not want to block this valuable carotenoid. Do not take Vitamin A palmitate as studies now indicate that it may increase the risk of macular degeneration and it may also increase the risk of osteoparosis, liver problems and neuro degenerative diseases. If you are deficient in Vitamin A then a physician needs to determine why and treat accordingly.

16. Get a good night’s sleep. More and more research is indicating that sleep deprivation is a major risk factor for many health problems. Sleep deprivation can suppress the immune system, increase inflammation in the body, lead to weight gain, high blood pressure and possibly Alzheimer’s disease. Sleep deprivation may increase your risk of optic nerve problems as well as macular degeneration. The National Sleep Foundation recommends 7-9 hours of sleep a night for adults.

17. Take a good nutritional supplement based Fortifeye Complete Plus | Click To Orderon the latest scientific data, preferably one that does not have any artificial dyes and synthetic nutrients. Be careful of supplements that have only “window dressing” amounts of specific nutrients. Many vitamin companies will add tiny amounts of popular nutrients just to be able to put it on the label. These small amounts may have no nutritional value. Patients must also be extremely careful not to take too many supplements as well. Vitamins can build up toxic levels, especially the fat soluble forms. The leading company that takes all of the current science into consideration in the development of their nutraceuticals is Fortifeye® Vitamins. The Fortifeye® products are all natural with no dyes. They provide therapeutic levels of nutrients and no window dressing. The Fortifeye Vitamins mission is stated as promoting proper vision and whole body health with the right ingredients at the right levels. I recommend to all of my patients the multivitamin Fortifeye™ Complete Plus, which Fortifeye Complete | Click To Orderis a combination of vitamins, minerals, phytonutrients, enzymes, whole foods and omega-3 essential fatty acids designed to lay a strong foundation for eye and total body health. If the patient has macular degeneration or is a smoker, I recommend Fortifeye™ Complete Macular Defense which is a nutritional system to help prevent any further vision loss from macular degeneration and gives the additional antioxidants necessary for smokers. I have seen many patients in clinical practice improve, some quite dramatically, while taking these supplements. Many doctors throughout the country are now recommending Fortifeye™ Vitamins to their patients with macular degeneration. Fortifeye stays abreast of the most current science in regards to nutritional supplementation for the eye and body, and because of this, their vitamins for macular degeneration and total body health are constantly evolving. Visit www.fortifeye.com for the latest information, or call toll free 1-866-503-9746.

Michael P. Lange, O.D.
Dr. Michael P. Lange
Board Certified Optometric Physician and Board Certified Nutritional Specialist

 

You can see that many patients will require a total overhaul in their dietary habits and lifestyles, and others will have some minor adjustments. If patients would only do these 17 things faithfully we would see much less vision loss from macular degeneration and have a much healthier society. Remember there is no miracle cure for macular degeneration. However if you implement the 17 steps outlined, you will decrease your risk of going blind from macular degeneration. Keep the faith!

 


Dr. Michael P. Lange

Board Certified Optometric Physician
and Board Certified Nutritional Specialist
Lange Eye Care and Associates
The Lange Eye Institute
(Located in Central/North Central Florida)
www.LangeEyeCare.com
Dec 27, 2009

Author: Dr. Michael P. Lange is a Board Certified Optometric Physician and a Certified Nutrition Specialist who started Lange Eye Care and Associates in Ocala, Florida, in March 1993. Lange Eye Care has grown to nine locations throughout the state of Florida with three Lasik centers. The Lange Eye Institute at The Villages in central Florida is home base for many of the nutritional studies that inspired the Fortifeye Brand of vitamin supplements. Dr. Lange is one of the first doctors in the industry to utilize intracellular blood tests and blood absorption studies to improve the Fortifeye vitamin line. Dr. Lange travels the world for nutritional research gathering valuable information to continuously improve Fortifeye vitamin formulations. Dr. Lange is still involved in the clinical practice of eyecare. He is a guest lecturer, contributing author to many eyecare magazines, and a daily syndicated talk show host of ‘Ask The Doctor’ which broadcasts every weekday at 9 a.m. and Saturdays at 2 p.m. from Tampa Bay on radio stations throughout the country and video streaming all over the world via the Internet. Detailed information on the nutritional research Dr. Lange has been involved in, and the eye vitamins and whole body formulas he has formulated, are at www.Fortifeye.com. If you are looking for a great group of eye doctors in Florida go to www.LangeEyeCare.com. For more, read this article about Dr. Michael Lange, Ocala optometrist involved in research on nutrition and UV protection, or read this biography of Dr. Michael Lange, Ocala eye doctor (optometrist).

 

 

Fortifeye™ and the ABCs of Ocular Nutrition

Improve your retinal health by taking Fortifeye vitamins and utilizing acetyl L carnitine, alpha lipoic acid, gogi berry, and green tea. Learn about ORAC value, antioxidant power, endothelial growth factor, cardiovascular disease, avoiding beta carotene. Reduce the risk of cardiovascular disease by taking omega-3 essential fatty acid from omega three fish oil. Lutein increases macular pigment density and reduces wet macular degeneration.

Fortifeye™ and the ABCs of Ocular Nutrition
Fortifeye Vitamins
Fortifeye Vitamins

Right Ingredients.  Right Science.  Right for You.

“…promote proper vision and whole body health with the right ingredients at the right levels.”

The entire family of Fortifeye products has been created by doctors who understand that quality counts. Each nutrient was chosen based on the highest manufacturing standards and uptake ability by the body.

All Fortifeye products are produced in a GMP, FDA, NNFA and NSF approved facility that supplies products to the domestic nutraceutical industry. On a global basis Fortifeye is manufactured in an approved TGA facility, the leading regulatory authority for nutraceuticals world wide.

 

Vitamin A: back to top

A fat-soluble, antioxidant vitamin important for vision and bone growth, belonging to the family of chemical compounds known as retinoids. Night blindness – the inability to see well in dim light – is associated with a deficiency of vitamin A. This vitamin is needed for the formation of rhodopsin, a retinal pigment. Vitamin A is also needed for the development of a healthy cornea. Third world countries have a high percentage of Vitamin A deficiencies and need supplementation for the pregnant mothers and children. However most developed countries where the population is consuming animal proteins, fruits and vegetables are not deficient in Vitamin A and do not need to supplement. Vitamin A can build up in toxic levels in the body and cause liver problems, birth defects, osteoporosis, neurological problems and many other potential problems. Too much vitamin A may be linked to increased risk of macular degeneration. Since vitamin A deficiency is rare in the populations that are taking Fortifeye vitamins and the potential for vitamin A toxicity exists, Fortifeye has decided to take all vitamin A and beta carotene out of their supplements.

Vitamin B complex: back to top

Eight water-soluble vitamins that play important roles in cell metabolism.

Vitamin C: back to top

Right Ingredients. Right Science. Right for You.(L-ascorbic acid) The most widely taken dietary supplement, Vitamin C is an essential water soluble nutrient required in small amounts to allow a range of essential metabolic reactions. Vitamin C is required for the synthesis of collagen and to maintain healthy skin, tendons, ligaments, blood vessels, cartilage and teeth. Vitamin C is an antioxidant that protects the body against oxidative stress, and is needed as a coenzyme in many reactions. Recent studies suggest that higher vitamin C intake may be associated with reduction in heart disease, strokes, cancers, cataracts and rheumatoid arthritis and excessive amounts of vitamin C may be associated with increase in oxalates that may increase risk of kidney stones. New research indicates that supplementing with vitamin C reduces C-reactive protein (CRP), an inflammatory marker linked with an increased risk of cardiovascular disease, stroke, peripheral artery disease, diabetes and possibly macular degeneration. It may lower CRP as much as statin drugs without the potential side effects. Vitamin C was one of the nutrients in the AREDS study that was beneficial for macular degeneration. High dosages of vitamin C may be beneficial at lowering intraocular pressure in patients with glaucoma.

Vitamin D: back to top

Is a group of fat-soluble pro hormones in two main forms; D2 (meritocracies) and D3 (collectable). Vitamin D is naturally produced by the human body when exposed to sunlight. Vitamin D regulates calcium and phosphorus levels in the blood by promoting their absorption from food in the intestines, and by promoting re-absorption of calcium in the kidneys. It also promotes bone formation and internalization. Vitamin D affects the immune system by promoting interspersion, phagocytes, and anti-tumor activity. After Vitamin D is produced in the skin from sun exposure or consumed in food it is converted in the liver and kidneys to the active form called clairol and then is released into circulation to specific organs. Vitamin D deficiencies are now being linked to several diseases including hypertension, diabetes, tuberculosis, cancer, periodontal disease, multiple sclerosis, collagen vascular diseases, seasonal affective disorder, depression, Parkinson’s and macular degeneration. New science (NHANES III) indicates that patients with higher serum levels of vitamin D may reduce the risk of macular degeneration. Vitamin D has anti inflammatory properties associated with it that may prove beneficial to many health and eye related diseases including macular degeneration. More studies on the use of vitamin D3 and eye disease will be necessary to prove these beneficail aspects. Twenty minutes of sun exposure in fair skinned people (3 to 6 times longer in dark skinned) between 12 and 2 p.m. will produce approximately 10,000 IU’s of vitamin D3. Physicians are now recommending more sun exposure or additional Vitamin D thru foods or vitamins for the high risk populations: elderly, darkly pigmented people, patients on medications that may block the absorption of fat soluble vitamins and people that are not in the sun very often. It is a good idea to have blood calcidiol (25-hydroxy-vitamin D) levels measured especially if you are in a high risk group. This is a current classification level that can give you some guide lines:

• 0-14.9 ng/mL = Severely deficient
• 15.0-31.9 ng/mL = Mildly deficient
• 32.0-100.0 ng/mL = Optimal
• >100.0 ng/mL = Toxicity possible

Vitamin E: back to top

A fat-soluble vitamin in eight forms that is an important antioxidant. Naturally occurring vitamin E exists in eight chemical forms (alpha-, beta-, gamma-, and delta-tocopherol and alpha-, beta-, gamma-, and delta-tocotrienol).The natural forms are usually labeled with the letter “d” (for example, d-gamma-tocopherol), whereas synthetic forms are labeled “dl” (for example, dl-alpha-tocopherol). Of the eight forms, alpha-tocopherol is traditionally recognized as the most active form of vitamin E but new studies suggest that gamma tocopherol exhibits the anti-inflammatory effects. Vitamin E may help prevent or delay coronary heart disease by limiting the oxidation of LDL-cholesterol. Vitamin E may help prevent the formation of blood clots which could lead to a heart attack. It is one of the five nutrients in the AREDS study used to slow down the progression of macular degeneration. Some studies have linked vitamin E as having protective effects on the human lens and macula. New studies indicate that tocotrienols may be effective at inhibiting angiogenesis and having numerous other health benefits. This may prove in the future to be beneficial in diabetic retinopathy and wet macular degeneration. Vitamin E may also help decrease C-Reactive protein which is a risk factor for cardiovascular disease, stroke, peripheral artery disease, diabetes and macular degeneration.

Acai Fruit Extract:  back to top

Acai is a fruit that grows on a particular palm tree in the Amazon rainforest. It is classified as one of the “super fruits” due to its very high ORAC value. Acai has a very high concentration of anthocyanins, antioxidants, fiber, omega essential fatty acids, plant sterols, vitamins and minerals. This nutrient dense fruit has been associated with tremendous health benefits. Fresh acai berries have an ORAC value of about 16,700 per 100 grams, while freeze dried varieties of acai berry can have ORAC as high as 100,000 per 100 grams.

Acetyl-L-carnitine (ALCAR):  back to top

Acetyl-L-carnitine is the acetylated ester of the amino acid L-carnitine. This form much more readily crosses the blood brain barrier than the L-carnitine form and aids in the conversion of fat to energy. ALCAR has been shown in clinical studies to support and improve mitochondrial functioning especially when combined with alpha lipoic acid. Some studies suggest that ALCAR may improve mental clarity, cognition, memory and energy. ALCAR may prove useful in Parkinson’s, Alzheimer’s, depression, diabetic neuropathy and blood sugar control, heart disease, lung disease and macular degeneration. Early studies may prove the combination of ALCAR, COQ-10 and omega three essential fatty acids may have protective effects on macular degeneration.

Alpha-lipoic acid: back to top

An antioxidant postulated to be effective in preventing vitamin C and vitamin E deficiency. It is able to scavenge reactive oxygen species and reduce other metabolites, such as glutathione, maintaining a healthy cellular redox state. Lipoic acid has been shown in cell culture experiments to increase cellular uptake of glucose, suggesting its use in diabetes. Recent studies now suggest that alpha-lipoic acid combined with acetyl-L-carnitine may improve memory and support mitochondrial health. These new studies hypothesize that alpha lipoic acid could benefit dementia and Parkinson’s. Some studies indicate it may be useful in glaucoma patients.

Biotin (B7): back to top

Used in cell growth, the production of fatty acids, metabolism of fats, and amino acids. It plays a role in the Krebs cycle, the process in which energy is released from food. Biotin not only assists in various metabolic chemical conversions, but also helps with the transfer of carbon dioxide. Biotin is also helpful in maintaining a steady blood sugar level.

Bilberry: back to top

Bilberry (European blueberry) is a deep blue fruit with high levels of anthocyanin pigments that have been linked to multiple health benefits. In several studies, bilberry was shown to improve visual acuity at night as well as shortening the time to adapt to dark conditions and recover from glare – important for light-sensitive individuals during night time driving. New science suggests bilberry, like blueberries, may prove to be a potent inhibitor of VEGF and may be helpful in diabetic retinopathy, macular degeneration, heart disease and cancer. Bilberry has an ORAC value of approximately 9,000 per 100 grams.*

Blueberry/Kale/Spinach:
back to top

Research has shown increasing intake of antioxidants such as dark green leafy vegetables and dark berries may reduce the risk of macular degeneration and cataracts. Kale and spinach are very high in lutein, a carotenoid that increases macular pigment density in the retina that may have some protection against macular degeneration. Lutein also acts as an internal sunscreen to the retina by absorbing the harmful HIV (blue light) rays from the sun. Lutein may be beneficial at slowing down cataract formation. Blueberries have many health benefits. Studies are proving that blueberries decrease risk of cancers, reduce LDL cholesterol, guard against neurological diseases, relieve arthritis, strengthen immune system, promote urinary tract health and optimize ocular health. New research using blueberries has revealed inhibition of VEGF which may help in the protection of certain cancers, proliferative diabetic retinopathy and the wet stage of macular degeneration. The ORAC value of blueberry is about 6,552 per 100 grams, ORAC of kale is about 1,770 and the ORAC value of spinach is about 1515.

Boron: back to top

A naturally occuring element, boron has been shown to decrease excretion of calcium and activate estrogen and vitamin D. This may retard bone loss as you age and decrease the risk of osteoporosis.

Bromelain:  back to top

Found in abundance in pineapples, bromelain is not a single substance, but rather a collection of enzymes and other compounds. It is a mixture of protein-digesting enzymes called proteolytic enzymes or proteases. Bromelain is an anti-inflammatory agent. In addition to aiding in blood clot formation, it has also been proposed in the use of arthritis treatment. It aids in the absorption of quercetin (flavonoid). Super high dosages of bromelain may cause rapid heart beat.

Fortifeye™ Vitamins are the newest, most advanced nutraceuticals for your eyes and body. Compare Fortifeye to your current vitamins.

Calcium: back to top

A naturally occurring element, calcium is responsible for bone growth and maintenance. Calcium uptake by the body is known to decrease with age, weakening bones (osteoporosis), but calcium supplementation seems to slow that process.

Carotenoids: back to top

Substances that enable the body to synthesize retinoids. Carotenoids are organic pigments that are naturally occurring in plants and certain animals. New studies are now proving that beta-carotene may block the absorption of lutein. Lutein is a beneficial carotenoid that may improve the health of the macula. Beta-carotene may also increase the risk of lung cancer in smokers. New science suggests beta-carotene may increase risk of aggressive prostate cancer. Due to all the negative science regarding supplemental beta-carotene, Fortifeye Vitamins decided to remove all beta-carotene from their formulas.

Chromium:  back to top

An elemental metal which is thought to even out blood sugar metabolism, potentially helpful for diabetic patients. It is also a powerful antioxidant in one form.

Cinnamon Bark Extract:  back to top

Cinnamon has been used for thousands of years as a spice and for medicinal purposes. Cinnamon has been used as an aid in the common cold, help digestive problems and often used as an antimicrobial. More recently cinnamon has been useful in helping to control glucose, cholesterol and triglycerides in type 2 diabetics. Cinnamon has an ORAC score of 267,536 per 100 grams making it one of the most powerful antioxidants in the world. The numerous health benefits related to diabetes combined with the high antioxidant power makes cinnamon bark extract very appealing for total body as well as ocular health.

Cocoa Extract: back to top

Cocoa is the dried and fermented bean from the cacao tree where chocolate comes from. Cocoa is high in two specific flavanoids – epicatechins and polyphenols. The flavanoids from cocoa have been associated with many health benefits. Cocoa may improve circulation to the brain and heart and thus improve cardiovascular health and improve cognitive abilities. Cocoa may also be beneficial at lowering blood pressure and lowering LDL (bad cholesterol) and raising HDL (good cholesterol). The antioxidant power (ORAC Value) of cocoa is one of the highest of any food on the planet. The high amounts of antioxidant in cocoa may help to retard free radical damage in the body and slow down the age related degenerative diseases in the body and eyes. ORAC value of dry powdered cocoa is about 80,000 per 100 grams and dark chocolate has an ORAC value of approximately 13,000 per 100 grams.

Copper:
 
back to top

Naturally occurring, copper is used by the body along with zinc to maximize iron uptake. Copper is an essential nutrient to all humans. It is found primarily in the bloodstream, as a cofactor in various enzymes. Copper is one of five nutrients in the AREDS study used to help slow the progression of macular degeneration.

CoQ10 (Ubiquinone):  back to top

Coenzyme Q10 is an oil soluble vitamin-like antioxidant found in every cell in the body. The highest concentration is found in the mitochondria. The primary function is generating energy. CoQ10 levels decrease with age, certain medications and certain diseases. CoQ10 has been associated with health benefits in numerous diseases like: heart disease, diabetes, gum disease, Parkinson’s, cancer, macular degeneration and glaucoma. CoQ10 deficiencies have been linked to certain medications like statins, beta blockers and tricyclic antidepressants. New studies indicate that CoQ10 combined with omega three fish oil and acetyl-L-carnitine may have protective effects for macular degeneration. Good dietary sources of CoQ10 are salmon, sardines, herring, tuna and mackerel. CoQ10 is best taken with a meal to aid in absorption.

Cyanocobalamin (B12):  back to top

B12 is the most chemically complex of all vitamins. It is involved in the metabolism of every cell in the body and is crucial in DNA and fatty acid synthesis. Elevated homocysteine can be linked to B12 deficiency along with pernicious anemia. New
studies indicate that low B12 status may increase risk of cognitive impairment. B12 deficiency becomes more of a problem as we age and in true vegetarians. Since it is difficult for the elderly population to absorb B12, larger amounts of B12 are now being used in vitamin supplements to help decrease the chances of patients developing B12 deficiencies.

Docosahexaenoic acid (DHA):  back to top

An omega-3 essential fatty acid, DHA is most often found in fish oil. DHA is a major fatty acid in sperm and brain phospholipids, and especially in the retina. Dietary DHA can reduce the level of blood triglycerides in humans, which may reduce the risk of heart disease. Low levels of DHA cause reduction of brain serotonin levels and have been associated with ADHD, Alzheimer’s disease, and depression, among other diseases, and there is mounting evidence that DHA supplementation may be effective in combating such diseases. May be beneficial for macular degeneration and dry eyes. The DHA used in Fortifeye vitamins comes from the highest quality ultra purified triglyceride based fish oils. This natural form of fish oil maximizes absorption, has no after taste and is toxin free. New science is now proving that omega three may decrease the shortening of the end cap of a chromosome know as a telomere. Telomere shortening is seen as an indicator of biological aging, so omega three fish oil should be incorporated into any healthy anti-aging diet.

Eicosapentaenoic acid (EPA):
back to top

An omega-3 essential fatty acid, found most notably in oily fish. EPA is a polyunsaturated fatty acid that acts as a precursor for prostaglandin-3, which inhibits platelet aggregation. EPA is thought to be effective in lowering inflammation. May be beneficial for macular degeneration and dry eyes. Recent studies have suggested that EPA may affect depression and suicidal behavior. EPA may prove to be beneficial for breast cancer, as well as aid in treatment of multiple myeoloma. The EPA used in Fortifeye Vitamins comes from the highest quality (triple molecular distillation) triglyceride based fish oils. This natural form of fish oil maximizes absorption, has no after taste and is toxin free. New science is now proving that omega three may decrease the shortening of the end cap of a chromosome know as a telomere. Telomere shortening is seen as an indicator of biological aging, so omega three fish oil should be incorporated into any healthy anti-aging diet.

Folic acid (B9): back to top

Folic acid or B9 is extremely important during periods of rapid cell division and growth. This B vitamin is needed to produce healthy red blood cells and prevent anemia. Folic acid is essential for healthy homocysteine levels and in the prevention of neural tube defects in infants. Folic acid when combined with B12 and B6 will bring homocysteine levels down. New studies also indicate the combination of B12, folic acid and B6 will decrease the development of macular degeneration. Folic acid is extremely important and you don’t want to have a deficiency, however
there is a fine line between too little and too much. Too much folic acid is associated with cognitive decline and increased risk of certain types of cancer. General consensus as of 2010 is not to take more than 1000mcgs from natural and synthetic sources. Fortifeye Vitamins has cut back the amount of folic acid in their products to make sure the public doesn’t get too much from supplementing.

Gamma-linolenic acid (GLA):
back to top

An omega-6 essential fatty acid found primarily in vegetable oils such as evening primrose (oenothera biennis) oil, blackcurrant seed oil, or borage oil. From GLA, the body forms dihomo-gamma-linolenic acid (DGLA). This is one of the body’s three sources of eicosanoids (along with AA and EPA.) DGLA is the precursor of the prostaglandin PGH1, which in turn forms PGE1 and the thromboxane TXA1. PGE1 has a role in regulation of immune system function. GLA is unique among the omega-6 polyunsaturated fatty acids (linoleic acid, GLA, and arachidonic acid) in its potential to suppress tumor growth and metastasis. GLA may also improve tear production and aid dry eyes. GLA by stimulating PGE1 acts as an anti-inflammatory
as well.

Gogi berry: back to top

Gogi berry, or llycium berry, has been used for thousands of years in traditional Chinese medicine. Gogi berry has been named the “anti-aging berry” because of its nutrient dense profile and extremely high antioxidant power. Gogi berry is considered one of the “super fruits” since it has one of the highest ORAC scores of any edible fruit. The ORAC value of 100 grams of gogi is approximately 25,300. Gogi berry may be the richest source of zeaxanthin in the plant family. Studies reveal that intake of a modest daily amount of gogi berries markedly increases fasting plasma zeaxanthin levels. This aids in improving macular pigment density which may prove to be beneficial for macular degeneration. Early studies indicate that gogi berry may have some neuro protective qualities in protecting retinal ganglion cells in glaucoma. The gogi berry may also aid in dark adaptation. The gogi berry is a good source of essential and trace minerals, amino acids, vitamins, polysachrides and essential fatty acids. The nutritional value of the gogi berry is proving to be beneficial for ocular and overall health.

Grape seed extract:  back to top

Used extensively in Europe, grape seed extract is rich in polyphenols, compounds that have antioxidant properties some consider even greater than vitamin C and vitamin E. Beyond its antioxidant powers, it is thought to improve blood circulation and help strengthen blood vessels. It may reduce the risk of cardiovascular disease and cancer. Resveratrol is one of the polyphenols found in grape seeds that has enormous health benefits.

“Since the body does not produce all of the required elements for optimal health, supplements are critical for your best health.”

Green tea extract:  back to top

EGCG, a key antioxidant found in green tea, is thought to support retinal health and works particularly well when in presence of Vitamin E. According to researchers at the University of Kansas, EGCG is 100x more powerful as an antioxidant that Vitamin C and 25x more powerful than Vitamin E. EGCG may also inhibit the formation of new blood vessels (anti-VEGF); this may prove to be useful in supporting retinal health. Green tea has been linked to lower cancer risk, lower cholesterol, faster weight loss, neuro protection, improved cognitive abilities, healthier immune system, better diabetic control and may benefit arthritis. 100 grams of brewed green tea has an ORAC value of approximately 1253. There is some evidence that green tea may help slow down cataracts. New science is proving that green tea may slow down the degeneration of the end cap of the chromosome called a telomere. This makes green tea an anti-aging nutrition.

Hesperidin: back to top

A flavonoid glycoside that has been shown to reduce cholesterol and blood pressure experimentally. In some studies large doses of the glucoside hesperidin were shown to decrease bone density loss. Hesperidin has also been shown to have anti-inflammatory effects.

Iodine: back to top

A chemical element that is required in trace amounts by most living organisms, iodine is necessary for proper production of thyroid hormone.

Lutein:  back to top

A carotenoid found naturally in dark green leafy vegetables (spinach and kale) and other natural sources, this potent antioxidant is sorely lacking in the typical American diet. Lutein and zeaxanthin are the only carotenoids found in the retina of the eye. Lutein supplementation has been shown in landmark clinical studies to increase macular pigment density which may promote macular health. Scientists believe lutein helps filter out dangerous ‘blue’ light, helping to maintain the photoreceptor and retinal health. Lutein is now believed to have a protective effect on the retina and may help to slow down age related macular degeneration. Lutein may have some protective effects against cataract formation. Lutein is more readily available when greens are gently cooked or juiced versus the raw state.

“Clinical studies have shown that increasing supplemental intake of lutein increases macular pigment density in the retina. Low levels of macular pigment is common in patients with macular degeneration.”

Lycopene: back to top

A bright red carotenoid pigment, lycopene is a phytochemical found in tomatoes and other red fruits. Lycopene is the most common carotenoid in the human body and is one of the most potent carotenoid antioxidants. Studies indicate it may reduce the risk of cardiovascular disease, cancer, diabetes, osteoporosis, male infertility and even macular degeneration.

Magnesium: back to top

The chemical element required in trace amounts by the body for the basic nucleic acid catalysis. Magnesium is necessary to maintain the health of almost every organ in the body especially the heart, muscles, kidneys, bones and teeth. Found most notably in spinach, pumpkin seeds and halibut. Magnesium has shown promise in treating symptoms of autism and ADHD, when combined with vitamin B6. There is an association between low magnesium intake and diabetes. Studies indicate that consumption of magnesium may lower C-reactive protein and other signs of chronic inflammation. Inflammation is one of the root causes of many eye diseases.

Manganese: back to top

Elementally found in nature, manganese and in its various ionic states (II) function as cofactors for a number of enzymes.

Mangosteen fruit extract:  back to top

Mangosteen is grown in Southeast Asia and is considered one of the super fruits. Mangosteen is known as the “queen of tropical fruits” and is very high in polyphenols, xanthones and tannins. Mangosteen is known for its health promoting properties and has a high ORAC score. Research indicates that xanthones may support the immune system, maintain intestinal health, help stop free radical damage, and support cartilage, joint and respiratory health.

Molybdenum: back to top

A transition metal important in plant nutrition, and is necessary in animal and human nutrition. It is found at the active site of certain enzymes, including xanthine oxidase, important within the eye.

N-Acetylcysteine: back to top

A co-factor which aids glutathione to increase uptake and efficacy of free radicals as antioxidants. N-Acetylcysteine may be beneficial in certain types of cancer, COPD, bipolar disorders, schizophrenia, boosting the immune system, aiding in detoxification of the body, reducing duration of influenza and may help with chronic blepharitis and symptoms associated with dry eyes.

Niacin (B3):   back to top

A water-soluble vitamin which plays an essential role in energy metabolism in the living cell and DNA repair. It also plays a role in removing toxic and harmful chemicals from the body. Niacin, when taken in large doses, increases the level of high density lipoprotein (HDL) or good cholesterol in blood. New studies are using niacin as a vasodilator to improve circulation in patients that have experienced a vein occlusion in the eye.

Pantothenic Acid (B5):  back to top

A water-soluble vitamin required to sustain life and is critical in the metabolism and synthesis of carbohydrates, proteins, and fats.

Phosphorous:  back to top

An element (always found as a compound in nature) that is a component of DNA and RNA and essential for all living cells where it forms part of the structural framework of these molecules (ADP, ATP).

Pomegranate fruit extract:  back to top

Pomegranate known as the “royal fruit” is a rich source of antioxidants and polyphenols. Pomegranate has a moderate ORAC value of about 2,860 per 100 grams. Some of the health benefits claims of pomegranate are improved circulation to the heart, reduction of arterial plaque, reduction in blood pressure and LDL (bad cholesterol), protective effects for breast and prostate cancer, improvement in erectile dysfunction and may act as an anti-inflammatory. The antioxidant power, improvement in circulation and anti-inflammatory aspects of pomegranate may prove to be beneficial for good ocular health.

Pyridoxine (B6):  back to top

B6 is required for the synthesis of neurotransmitters and red blood cells. It is also necessary for healthy homocysteine levels. Supplementation with pyridoxine, folic acid and B12 reduces the concentration of homocysteine in the bloodstream. Elevated homocysteine is a risk factor for heart disease, stroke, macular degeneration and occlusive artery disease in the eye. Super high dosages of B6 may cause nerve damage in the legs and arms.

Quercetin dehydrate:  back to top

A flavinoid found in such food as citrus and apples, quercetin may have positive effects in combating or helping to prevent cancer, heart disease, cataracts, allergies, inflammations, and certain respiratory conditions. Patients should make their doctors aware if taking high dosages of quercetin prior to antibiotic therapy.

Resveratrol:  back to top

Found in the skin of red grapes, resveratrol is perhaps one of the most potent antioxidants known. Research shows that resveratrol has anti-vascular endothelial growth factor (anti-VEGF) which they believe offers the greatest degree of protection to human blood-vessel cells, particularly within the retina. New studies indicate it may increase life span. Resveratrol may be useful as a chemo-protectant, cardio-protectant, anti-inflammatory, neuro-protectant and may prove useful for diabetes. Fortifeye was one of the first in the industry to utilize resveratrol in their formulas.

“Current studies show that certain nutrients can actually slow or stop the development of unwanted blood vessels (called vascular endothelial growth factor, or “VEGF”). Therefore, nutrients with anti-VEGF properties such as green tea, resveratol, turmeric, and soy isoflavones are tremendously important for overall ocular health, particularly for diabetics or patients with macular degeneration.”

Riboflavin (B2):
 
back to top

Required for a wide variety of cellular processes; like the other B vitamins, it plays a key role in energy metabolism. Riboflavin is required for the metabolism of fats, carbohydrates, and proteins. Deficiencies can cause corneal and lenticular opacities.

Rutin: back to top

A citrus flavonoid glycoside and antioxidant. It has been suggested that rutin might play an important role in inhibiting some cancers, as well as strengthening the capillaries, including those in the choroid. Rutin is also an inhibitor of VEGF which may prove useful in diabetic retinopathy and wet macular degeneration.

Selenium: back to top

A trace element not naturally produced by the body, selenium is found in high concentration in nuts. Selenium functions as cofactor for reduction of antioxidant enzymes such as glutathione peroxidases and thioredoxin reductase.

Sesame lignans: back to top

Powerful antioxidants that have been shown to work within the essential fatty acid derivatives (GLA) to create positive enzymatic reaction as compared to negative prostaglandin reactions. Sesame lignans help to block the inflammatory cascade of arrachidonic acid inherent to omega six oils.

Taurine: back to top

Compound that in recent laboratory studies have shown that taurine can influence (and possibly reverse) nerve blood flow, motor nerve conduction velocity, and nerve sensory threshold defects. In certain animal cases, the absence of taurine causes central retinal degeneration.

Thiamine (B1): back to top

Plays an important role in helping the body convert carbohydrates and fat into energy. It is essential for normal growth and development and helps to maintain proper functioning of the heart and the nervous and digestive systems. Thiamine is water-soluble and cannot be stored in the body. However, once absorbed, the vitamin is concentrated in muscle tissue.

Turmeric (Curcumin): back to top

Naturally occurring in turmeric, curcumin is in curry spice. Curcumin is known for its anti-inflammatory, chemoprotective, antioxidant, anti-amyloid and anti-VEGF (anti-vascular endothelial growth factor) properties. Studies indicate this compound may be beneficial in inflammatory diseases in the eye and may prove to be effective in slowing down certain types of cataracts. New studies indicate it may decrease chances of developing dementia.

“Thousands of patients are currently using Fortifeye Complete Plus combined with proper diet and exercise to dramatically improve their quality of life.”

 

Vanadium: back to top

A trace metal most popularly added to drinking water in Asia. It has been suggested that vanadium improves blood sugar control, and increases muscular strength, as well as osteoporosis treatment.

Zeaxanthin:  back to top

Zeaxanthin is one of the two carotenoids contained within the retina of the eye. Zeaxanthin and lutein have an almost identical chemical structure and have similar properties. Zeaxanthin, like lutein, increases macular pigment density and also helps to filter out the harmful blue light from the sun. Gogi berries have one of the highest sources of zeaxanthin and orange bell peppers are relatively high in zeaxanthin and more readily available. Zeaxanthin may also have some protective effects on cataract formation. Zeaxanthin may inhibit VEGF and prove useful for diabetic retinopathy and wet macular degeneration.

Zinc: back to top

A trace metal, zinc is an activator of certain enzymes, such as carbonic anhydrase, important in the transport of carbon dioxide in blood. Clinical studies have found that zinc, combined with antioxidants and certain vitamins (A, C, and E) may delay progression of age-related macular degeneration. Also, significant dietary intake of zinc has also recently been shown to impede the onset of flu. Fortifeye Vitamins uses Opti Zinc to gain superior absorption and bio availability over other forms of zinc.

 

IMPORTANT NOTE: These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent disease.

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