Ask the Doctor Radio Show from 2-6-16 with Dr. Michael Lange

Proper Nutrition and Dry Eyes

Proper Nutrition and Dry Eyes

Michael P. Lange OD, CNS, 10/24/2011

Dry eyes can be improved through proper nutrition. The vast majority of dry eye patients will notice a significant improvement in dry eye symptoms once the correct dietary and lifestyle modifications are implemented. Dry eye is a nutritionally responsive condition and this paper will discuss how proper diet and supplementation may improve subjective and objective signs and symptoms of dry eyes.

Most of our patients, whether fat or thin, are nutritionally compromised. Very rarely will you meet a patient that is of ideal body weight, medication free and on a truly healthful diet. As a clinician you will know at the first glance of your patient and after a brief discussion how critical a dramatic adjustment in their diet is going to be to their overall health and their dry eyes. Proper nutrition is one of the most important single factors in maintaining the health of our patients. Most people in today’s society are not getting the required vitamins, minerals and essential fatty acids from the foods they are eating. We have become a society living ‘life on the go’ that is fueled by fast food and junk food. Our typical diet is caloric dense and nutrient deficient. Americans consume a diet that is unbalanced—with too many omega-6 fatty acids and not enough omega-3 fatty acids—leading to increased inflammation and disease in the body. This is associated with increased levels of cytokines, proteins that trigger inflammation. Inflammation is one of the root causes of dry eye syndrome (keratoconjunctivitis sicca) and many other systemic diseases. Our foods are processed, sugar- and salt-laden, filled with trans fats, hydrogenated oils, high fructose corn syrup, synthetic dyes, chemicals and artificial sweeteners. These poor nutritional habits combined with a sedimentary lifestyle are why the health of the American people (our patients) is becoming compromised. America is home to the most obese people in the world. According to the CDC (Center for Disease Control and Prevention) obesity in adults has increased by 60% within the past twenty years. A staggering 70% of American adults are overweight or obese and obesity related deaths have accelerated to more than 300,000 a year, second only to tobacco related deaths.

Dietary modifications and lifestyle changes

Dr. Lange recommends everyone learn the 'dirty dozen' fruits and vegetables
Dr. Lange recommends everyone learn the ‘dirty dozen’ fruits and vegetables

Most nutritional experts recommend 10-13 servings of organically grown fruits and vegetables a day. Americans are falling short of this amount and are becoming more and more nutritionally compromised. 70% of adults are not even consuming five portions of fruits and vegetables a day. The population that consumes the least amount of vegetables and fruits are more predisposed in developing disease and illness. These large and growing groups of people are nutritionally compromised and more prone to develop free radical damage in their bodies and eyes. These are the patients who are more prone to have dry eyes, cataracts and retinal disease. I have seen in clinical practice for close to twenty years the positive effects dietary modifications and lifestyle changes can have directly on ocular health and total body health.

I have finally come to the realization that patients who will follow a combination of the Mediterranean, paleo or hunter gatherer type of diet, eating more like our ancestors, along with regular exercise and proper sleep benefit significantly. This is a diet that consists of organically grown fruits, vegetables, seeds, nuts, whole grains, proteins and mainly water and a few other beverages. I recommend patients avoiding water that is in plastic bottles and drinking water that is filtered or in glass bottles due to the potential for bisphenols leaching into the water from the plastic. Bisphenols cause endocrine disruption which will compound a dry eye problem. Bisphenols are in plastic bottles as well as in canned foods. F, D and C red yellow and blue dye can also cause endocrine disruption and so should be avoided. Dyes are in just about everything we consume these days, so teach your patients to be proactive in their health and read labels. I recommend patients try to consume half their body weight in ounces of good quality water daily. I also advise patients to try to substitute their morning coffee with organic green tea and lemon. The antioxidant and anti inflammatory effects of green tea and lemon have significant health benefits and many of my patients will notice symptomatic relief of their dry eyes from this one simple step. I advise my patients to try to eat 10-13 servings of fruits and vegetables on a daily basis. I recommend “the dirty dozen” fruits and vegetables be only organically grown due to their high amounts of pesticide found inside this specific group. Most of us have an accumulated build up of pesticide exposure in our bodies due to numerous years of exposure. This “chemical burden” leads to a variety of serious health issues that may potentiate a dry eye condition. The protein in this particular type of diet should always be free range organically raised or wild, not farm raised! Try to get your patients to eat fish at least three times per week to improve the omega three to omega 6 ratio in their blood. The fish that is highest in omega three and lowest in potential contaminants are sardines, anchovies, herring, mackerel, wild rainbow trout and wild Alaskan salmon. Some of your patients will follow your directions precisely; however the majority is going to wonder off of these specific recommendations. This is why supplementation with antioxidants and omega-3 fatty acids is so important.

Blood chemistry testing

How do you know the specific nutritional status of your patients without testing them? The only accurate way to test for these deficiencies is through blood testing. We will routinely do three special blood tests to gain valuable insight into the nutritional health of our patients. A SpectraCell intracellular blood test, vitamin D 25 OH and an omega-3 index test will help determine what your patient’s nutritional status is and if they have nutritionally modifiable risk factors for ocular conditions like dry eyes. You will quickly see that almost everyone you test is deficient in antioxidants and omega three. Many of these patients will also have elevated CRP, homocystein, triglycerides, cholesterol and arachidonic acid. The majority of these blood chemistries can be positively impacted through proper nutrition. The poor results on these tests can help motivate your patients to making these crucial dietary and lifestyle modifications that will positively impact their overall health. After reviewing the results of these tests with your patients they will finally understand the benefit of proper supplementation. Realistically, due to these tests not being covered by Medicare or insurance, not everyone will be able to have these tests done because of the cost. Let’s now review the specific protocol that is working extremely well with the dry eye population.

Omega-3 fish oil

The majority of large clinical studies that have documented the positive health benefits of omega-3 fatty acids have utilized fish or fish oil consumption. There is a multitude of positive studies supporting the beneficial health aspects of a higher consumption of omega-3 from fish oil or fish. The medical community has readily embraced these positive health benefits and is prescribing and recommending fish oil supplements to their patients. The increased public awareness regarding omega 3 fish oil has created an omega-3 explosion. Consumers that are in tune with prevention and wellness are becoming proactive in their health and practicing prevention by consuming more fish or purchasing fish oil supplements from the drug store, health food store or through the Internet. However, one must be careful with consuming too much fish because of the potential contaminants that are in particular types of fish. With all of the contamination in the oceans it is becoming more and more difficult to recommend consuming large amounts of fish. The consumer or patient must also be aware that all fish oil is not created equal! The health care professional should be educating their patients on the benefits of proper omega-3 supplementation.


Fish Oil Demo with Dr Michael Lange
Ethyl ester based fish oil eats Styrofoam!

Omega-3 fish oil has two readily available forms: ethyl ester fish oil and triglyceride form fish oil. I recommend purchasing the triglyceride form fish oil over the ethyl ester version of omega-3 fish oil for a variety of reasons. The ethyl ester form of fish oil is highly unstable and therefore it can oxidize and become rancid quicker than the triglyceride form of fish oil. Many of the ethyl ester fish oils may become rancid before you purchase them. This is one of the reasons many people get a nasty aftertaste or have problems burping up an unpleasant fish taste from the ethyl ester form of fish oil. Studies also indicate that the triglyceride form omega-3 fish oil absorbs much faster and more efficiently therefore increasing bio availability. Most fish oil that is being sold OTC or as a prescription in the United States is the ethyl ester version because it is significantly less expensive to manufacture. The final phase in the purification of a triglyceride form of fish oil requires the ethyl ester molecule to be cleaved off and replaced with a triglyceride molecule, thus making it a more natural omega-3 fish oil than the ethyl ester version. The triglyceride form of omega-3 fish oils are extremely pure and concentrated making them the ideal choice for your patients. If you do not know if your fish oil is an ethyl ester version or triglyceride version you should call the customer service department on the back of the bottle. You can also squeeze the contents of your fish oil into a Styrofoam cup and watch for the chemical reaction. If the cup begins to dissolve after 10 to 20 minutes, then you have an ethyl ester form. However, some fish oils with very low concentrations of ethyl ester fish oil may not dissolve the cup. When shopping for the best triglyceride form fish oil, look for high levels of EPA and DHA. I recommend finding an omega-3 fish oil supplement that has an EPA between 400-450 per gel cap and a DHA around 250-300 per gel cap. These are the levels I have studied using the latest in omega-3 blood testing and have found that the consumption of two gel caps a day of this concentration can increase your omega index to a desirable level over 8%. This omega-3 index measures the concentration of EPA and DHA as a percent of total essential fatty acids in the red blood cell membranes. Recent research is proving that the desirable level for cardio protection is an omega index over 8%. This research claims that levels greater than 8% correlate with a 90% reduction in the potential for a fatal heart attack. The vast majority of Americans have an omega index closer to 4%.

Best sources of omega-3

Fortifeye Super Omega Fish Oil
Fortifeye Super Omega Fish Oil

My research team and I have tested a variety of omega-3 oils from flax, krill and ethyl ester fish oils and have not found nearly the improvements in the omega index with these other types of omega-3 fatty acids. So all omega-3 supplements are not created equal! Most of the inferior brands of fish oil and krill oil you can purchase OTC have no therapeutic value and won’t move the omega index very much. Many of the OTC fish oils are also filled with higher than the acceptable amounts of contaminants like PCB. Is this something you want to recommend to your patients? After years of study, a lot of trial and error and a one month research trip to Norway, I developed a highly purified triglyceride omega-3 fish oil concentrate with an outstanding 1600mg of omega-3 (EPA 860mg, DHA 580mg) in just two gel caps! The teams at Fortifeye Vitamins and the Omega 3 Test have been actively studying the influence of two daily capsules of this concentrated Super Omega on blood levels of omega-3 and the results have been astounding! After just thirty days, mean blood levels of omega-3 have increased from 4.2% to 9.1% with some patients as high as 11%! The results are a true testament to the benefits of proper levels of omega-3 supplementation. These are the levels that have produced positive results in our dry eye population. Most patients do quite well on two per day dosing of these levels and will start to experience symptomatic relief in 1-3 months. If the patient is over 250 lbs or has a significant dry eye problem I would recommend doubling the dosage. We have positive results using these levels of omega-3 fish oil with our MGD patients, those with recurrent hordeolums, conjunctivitis, chronic low grade uveitis, blepharitis and we are even seeing positive impact on our diabetic maculopathies and macular degeneration patients. Based on the current world wide research available, combined with the ongoing research being done at Fortifeye Vitamins, I feel the primary eye care provider should be making omega-3 recommendations to all of their patients. EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) are the two principal EFAs (essential fatty acids) found in fish known as omega-3 fatty acids. The current research suggests the anti-inflammatory effects of fish oil may help with dry eye syndrome. EPA generates the anti-inflammatory eicosanoids prostaglandin E3 and leukotriene B5. If the concentration of EPA is high enough the EPA blocks the delta-5 desaturase enzymatic step that stops the conversion of omega-6 EFAs to the inflammatory cascade of arachidonic acid (AA). This allows more conversion to anti-inflammatory prostaglandin E1 (PGE1). PGE1 then binds to EP2 and EP4 receptors to activate adenylate cyclase and increase cyclic AMP (adenosine monophosphate) which in turn stimulates a healthier tear production. DHA also decreases production of pro-inflammatory eicosanoids and helps to balance the body’s response to inflammation. Both EPA and DHA contribute to reducing inflammation in somewhat different but complementary mechanisms. The increase in omega-3 EFAs has also shown to improve dysfunction in the meibomian gland with a much thinner and clearer meibomian gland secretion, thus helping with meibomian gland dysfunction. The increased consumption of a triple molecularly distilled and concentrated triglyceride form omega-3 fish oil will help to get the balance between omega-6 and omega-3 in better harmony and allows for less inflammation in the body and eyes. Americans have too high a percentage of pro-inflammatory omega-6 in their diet. The addition of some good omega-3 fish oil is the start to a healthier body and visual system.

Astaxanthin

Fortifeye Focus
Fortifeye Focus – An astaxanthin, lutein and zeaxanthin super carotenoid supplement designed and recommended by Dr. Michael Lange, OD CNS.

A relatively new nutrient used in supplements that comes from the micro alga haematococcus pluvialis, astaxanthin is proving to have multiple health benefits. The super carotenoid astaxanthin is the reason lobsters, shrimp, crabs and wild salmon have a reddish color. Astaxanthin is an extremely potent antioxidant and anti-inflammatory. Clinical studies have now proven that 6mg of astaxanthin can improve the blood flow to the eye and actually aid in accommodation (focusing) and in reducing eye fatigue. Astaxanthin reduces inflammatory markers such as C reactive protein (CRP), nitric oxide synthase (NOS), prostaglandin E2 (PGE2) and tumor necrosis factor (TNF). Astaxanthin is documented with high potencies for neutralizing oxygen radicals. For example, it is 550 times more powerful than vitamin E and 40 times more powerful than beta-carotene against singlet oxygen radicals. These remarkable aspects of astaxanthin are why Fortifeye Vitamins and The Lange Eye Institute are involved in some ongoing clinical blood studies to look more carefully at the anti inflammatory properties of astaxanthin. Early data shows that when combined with Fortifeye Super Omega, 6 mg of astaxanthin is lowering arachidonic acid levels more than the fish oil alone. Studies also indicate that astaxanthin may help in muscle recovery and reduce muscle fatigue. Many patients taking supplemental astaxanthin have also noticed the sun block properties this powerful antioxidant exhibits. Astaxanthin has also been linked to healthier skin and less fine lines and wrinkles have been documented after taking astaxanthin for a few months. Astaxanthin is a truly unique nutrient with some incredible health benefits. I have been very impressed with the potential ocular and overall health benefits of astaxanthin. Dry eye and eye fatigue often times go hand in hand especially in computer vision syndrome (CVS). The typical patient that comes in complaining of eyes that feel tired, fatigued, dry, sandy and gritty after working on the computer for prolonged periods of time are the ones that will benefit from adding 6mg of astaxanthin to their supplement regiment. I will usually start these patients on a combination of omega-3 fish oil and 6 mg of astaxanthin and after three months many of these patients’ symptoms have resolved or improved significantly. These patients will also commonly report an improvement in many other areas: less joint pain, healthier skin, improved energy, improved muscle recovery, more endurance, improvement in focusing and many more. I have seen a synergy with triglyceride form fish oil while using astaxanthin in my dry eye population. If patients are not experiencing the relief they are looking for on omega-3 supplementation alone I will add 6 mg of astaxanthin and see the patient back in three months for follow up. I have been amazed at the positive feedback I have received from these patients. Not only are these patients improving subjectively but their objective signs of dry eye are also improving. I think astaxanthin has a place in eye care especially for the patients who are looking for a more natural approach to help with their dry tired eyes. Think about how many patients the combination of omega-3 and astaxanthin may help in your practice. Just about everyone these days is experiencing some form of dry and fatigued eye symptomology throughout the day. Patients are grateful when you help solve their complaints without recommending surgery or medication.

Gamma-linolenic acid

The moderate to marked dry eye patients may need one additional nutrient in conjunction with the omega-3 and astaxanthin to maximize the nutritional approach for dry eyes. Gamma-linolenic acid (GLA) is an essential fatty acid (EFA) in the omega-6 family that is found mainly in plant seed oils. The three most common plant seed oils where GLA are found are borage seed oil, black currant oil and evening primrose oil. GLA is broken down in the body to dihomo-gamma-linolenic acid (DGLA) and arachidonic acid (AA). DGLA competes with AA and prevents the negative inflammatory effects that AA would otherwise cause. Adequate amounts of magnesium, zinc and vitamins C, B3 and B6 help to promote the conversion of GLA to DGLA rather than AA. It is fairly rare that our patients will have deficiencies in these areas if eating the appropriate foods. However, many of our patients are not getting the appropriate nutrition in their diet and must supplement with a good whole body anti-oxidant. Running a SpectraCell nutritional blood panel may help find many surprising nutritional deficiencies your patients have. Researchers in Japan have shown that astaxanthin may suppress the cyclooxygenase enzyme and decrease the amount of pro-inflammatory PGE2 produced. Once the AA pathway is blocked the DGLA is free to convert to anti-inflammatory prostaglandin E1 (PGE1) and stimulation of tear production occurs. Recent studies suggest that oral GLA supplementation improved dry eye both clinically and subjectively in patients with dry eye syndrome. Studies also show that patients who take a combination of linoleic acid (LA) and gamma-linoleic acid (GLA) prior to and after refractive surgery may have better tear production and less dry eye complications. Studies utilizing GLA and omega -3 fish oil have shown an additive anti-inflammatory effect with no elevation in arachidonic acid. Due to the extremely high amounts of omega-6 in most diets I began studying different ratios of omega-3 and GLA and have decided to use a ratio of approximately 10 to 1 omega-3 to omega-6 (GLA) to maximize the anti-inflammatory effects and gain full advantage of both types of essential fatty acids. If the ratio of omega-6 (GLA) to omega-3 is too high in the omega-6 direction then the possibility of more inflammation related to the high omega-6 low omega-3 ratio exists. Currently for my more advanced dry eye cases I have been using 1600 mg of triglyceride form omega-3, 160 mg of GLA from black currant seed oil, 6mg of astaxanthin and a good whole body anti-oxidant with great results. These patients not only experience ocular health benefits but also notice many general health benefits as well. It is time that both optometrists and ophthalmologists start to utilize the power of proper nutrition to help their patients. It is a win-win for everyone involved.

I really think having educational information as well as supplements available at your office is the smart way to go. This enables the doctor to have some control over the quality of supplements the patient is taking. Once the patient walks out of your door they may buy the cheapest thing they can find on the Internet or warehouse club that has no therapeutic value whatsoever! Educating your entire staff on the importance of proper nutrition is very important as well. Everyone from the front desk to the technicians should be educated on the benefits of proper nutrition. It is a team approach.

Dr. Michael P. Lange, O.D., C.N.S.
Dr. Michael P. Lange
Board Certified Optometric Physician and Board Certified Nutritional Specialist

Dr. Michael P. Lange, OD CNS
Board Certified Optometric Physician
Certified Nutrition Specialist
Syndicated Daily Talk Show Host (Ask the Doctor)
CEO and founder of Lange Eye Care and Associates
CEO and founder of the Lange Eye Institute
CEO of Lange Sun and Nutrition Centers
www.langeeyecare.com
www.fortifeye.com
www.drmichaellange.com
October 24, 2011

 

Lange Eye Care Locations

Gainesville Office
Lange Eye Care and Associates
3968 SW Archer Road W101
Gainesville, Florida 32608
Phone: 352-376-6622

Ocala Office
Lange Eye Care and Associates
3101 SW College Road
Ocala, Florida 34474
Phone: 352-237-3768

Triple Crown Plaza Office
Lange Eye Care and Associates
11100 SW 93rd Court Road
Suite 15
Ocala, Florida 34481
Phone: 352-291-2000

Summerfield Office
Lange Eye Care Vision Outlet Center
Unit #604 Highway 441S
Summerfield, Florida
Phone: 352-307-3273

Inverness Office
Lange Eye Care and Associates
3808 E. Gulf to Lake Highway
Inverness, FL 34453
Phone: 352-344-5110

Clearwater Offices
Lange Eye Care Optical Gallery & LASIK Center
23666 U. S. Highway 19 North
Clearwater, FL 33765
Phone: 727-791-1214

Lange Sun and Nutrition Center
2551 Drew Street
Suite 302
Clearwater, FL 33765
Phone: 727-216-6275

Williston Office
Lange Eye Care And Associates
129 S. W. 7th Street
Williston, FL 32696
Phone: 352-528-0433

The Villages Office
Lange Eye Institute
466 and CR101
The Villages, Florida
Phone: 352-753-4014

 

 

 

 

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More information: Dr. Michael P. Lange is a Board Certified Optometric Physician and a Certified Nutrition Specialist who started Lange Eye Care and Associates in Ocala, Florida, in March 1993. Lange Eye Care has grown to nine locations throughout the state of Florida with three Lasik centers. The Lange Eye Institute at The Villages in central Florida is home base for many of the nutritional studies that Fortifeye is involved in. Dr. Lange is one of the first doctors in the industry to utilize intracellular blood tests and blood absorption studies to improve the Fortifeye vitamin line. Dr. Lange travels the world for nutritional research gathering valuable information to continuously improve Fortifeye vitamin formulations. Dr. Lange is still involved in the clinical practice of eyecare. He is a guest lecturer, contributing author to many eyecare magazines, and a daily syndicated talk show host of ‘Ask The Doctor’ which broadcasts every weekday at 9am and Saturdays at 2pm from Tampa Bay on radio stations throughout the country and video streaming all over the world via the Internet.

 

 

 

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Macular Degeneration Treatment, Macular Degeneration Vitamins & Retina Care in Ocala, Gainesville, The Villages and Clearwater

Macular Degeneration Treatment, Macular Degeneration Vitamins & Retina Care in Ocala, Gainesville, The Villages and Clearwater

Macular degeneration research at Lange Eye Care in Ocala, Florida, is using the latest in nutrition and vitamins for macular degeneration.

Topcon® 3D OCT - New Technology at Lange Eye Care
Topcon® 3D OCT, a new technology at Lange Eye Care. The New Topcon OCT enables the doctors at Lange Eye Care to have the most advanced diagnostic technology to aid them in making the most accurate and early diagnosis of diseases of the eye. This technology will help to detect vision threatening diseases much earlier and thus initiate treatment earlier for a better visual outcome.

If you are looking for the very latest in macular degeneration treatment and macular degeneration surgery, Lange Eye Care in Ocala and Gainesville may be what you are looking for. Ocala retina care and Gainesville retina care has many different options. If you have macular degeneration, think very carefully where you want to go.

What is Macular Degeneration?

What is macular degeneration? Macular degeneration is the leading cause of vision impairment and legal blindness in the United States after the age of 55. Much of this progressive vision loss is unnecessary! The typical American is eating a diet that is convenient and quick. These foods are high in omega six, low in omega three, high in saturated fat, high in sugar, high in salt and overly processed and preserved. Americans are rapidly becoming an obese nation due to their poor dietary habits and sedimentary lifestyle. The foods are nutrient depleted and therefore the vast majority of the population is becoming sluggish and tired with no energy and as a result is becoming over weight. Obesity is a cause for many systemic diseases like high blood pressure, diabetes, elevated cholesterol, elevated triglycerides, elevated homocystein and elevated C-reactive protein. All of these are modifiable risk factors for macular degeneration.

Dry Macular Degeneration Treatment in Ocala, Gainesville, The Villages

Patients with macular degeneration need to see a doctor that is in tune with the latest in nutrition that will help their patient become proactive in their current and future health. Many patients when counseled on proper nutrition and lifestyle adjustments can actually slow down the degenerative aspects of macular degeneration. Dry macular degeneration treatment now consists of eye vitamins, lifestyle and dietary adjustments. The combinations of these three are considered treatment for dry macular degeneration.

Nutritional Retina Care in Ocala

Fourier Domain OCT – Optical Coherence Tomography. This new technology commonly known as Fourier Domain OCT or Spectral Domain OCT makes it possible to visualize large areas of the retina, significantly enhancing OCT’s diagnostic utility. Lange Eye Care is the only optical group to have this technology in the five county radius.

Lange Eye Care has doctors on staff who are in tune with all the latest in nutritional intervention and lifestyle modifications for macular degeneration. Many of the doctors at Lange Eye Care are involved in macular degeneration research using the latest in proper nutrition and vitamins for macular degeneration. Nutritional retina care in Ocala is an area that Dr. Lange and his staff of optometrists and ophthalmologists are involved in. Dr. Lange states, “I have also seen many patients actually improve when their diet, supplements and lifestyles are adjusted.”

New Treatment for Macular Degeneration

It takes discipline for a patient to follow the appropriate dietary and lifestyle modification plan. Dr. Lange likes to start out with a complete nutritional blood test (SpectraCell) that looks at all blood chemistries and also looks for any nutritional deficiency a patient may have. He also likes to get a vitamin D, 25-OH blood test and an omega-3 /omega-6 blood test. The combination of these tests will enable the doctor to develop a customized nutrition plan that is individualized for each patient based on scientific objective data. If the patient is put on a proper diet and/or supplement plan many of their nutritional deficiencies will resolve. This is crucial for great retina care in Ocala, Dr. Lange asserts. These nutritional deficiencies are corrected, then systemic health issues that are risks for macular degeneration may start to resolve. The staff at Lange Eye Care and Dr. Michael Lange have been using this philosophy for many years with great success when dealing with macular degeneration patients in Ocala and Gainesville.

Macular Degeneration Vitamins

Omega-3, B-12, glutathione and vitamin D-3 deficiencies are quite prevalent in the macular degeneration population in the Ocala and Gainesville areas. All four of these deficiencies are modifiable risk factors that can be changed very quickly with proper diet and supplements without using medication. Once these deficiencies are corrected we see pro inflammatory omega-6, arachidonic acid and C-reactive protein levels improving. Many patients will also notice an improvement in their cholesterol, homocystein and triglycerides once these nutritional deficiencies are eliminated. When the nutritional deficiencies start to resolve the patient will have more energy and a better sense of well being. These improvements will enable them to start a more vigorous exercise routine of both cardio and weight bearing exercises that will improve circulation to the eye and entire body and aid in this nutritional rehabilitation.

Sleep Deprivation, Inflammation and Stress

One more very important part to the equation for macular degeneration patients is proper amount of sleep. Sleep deprivation is another cause of inflammation and the build up of a stress hormone called cortisol in the body. “The proper amount of sleep combined with nutritional rehabilitation is very powerful at quelling the fires of inflammation in the body,” says Dr. Michael Lange, optometrist and nutrition specialist with Lange Eye Care. Proper nutrition, exercise and proper sleep act synergistically at promoting good overall health and good ocular health. These combinations can be considered a form of treatment for macular degeneration. Dr. Lange states, “Macular degeneration treatment doesn’t always entail medications, injections and surgery.”

Vitamins for Macular Degeneration

Vitamins for macular degeneration are becoming mainstream and treatment of choice for the dry form of macular degeneration. Eye vitamins should be recommended by the doctor once a diagnosis of macular degeneration is made. The eye care provider needs to work very closely with the patient’s primary care physician, internist and cardiologist to complete the team approach of total health care for each patient. The eye is the window to the body and only the optometrist or ophthalmologist is trained at looking carefully at the structures inside the eye. The optometrist and ophthalmologist can look at the vascular and nerve networks in the eye and see how systemic disease, medication and diet can have profound effects.

Macular Degeneration Research

The Lange Eye Institute in The Villages, Florida

So who better than your eye doctor to help you to plan a total program for you to combat against free radical damage in the eye and body? Lange Eye Care and Associates was one of the first eye care centers in the country to utilize the very latest in intracellular nutritional blood analysis and genetic testing to help macular degeneration patients. Dr. Michael Lange and many of the doctors on staff at Lange Eye Care are involved in nutritional studies using the latest in nutritional rehabilitation for macular degeneration patients. Patients with retinal disease travel from hundreds and thousands of miles away to come to The Lange Eye Institute in The Villages, Florida, for the latest in nutrition for macular degeneration. Ocala, Florida, is the home of Lange Eye Care, and this is where this form of prevention for macular degeneration began. Patients with macular degeneration have been going to Lange Eye Care for almost twenty years to gain valuable insight into the very latest in macular degeneration treatment in Ocala, The Villages or Gainesville.

Providing Expert Retina Care in Ocala, Gainesville, The Villages and All Surrounding Areas

Whether the need is nutritional, medical or surgical, the experts in retina care in Ocala at Lange Eye Care are available seven days a week. Dr. Michael Lange started his first eye care center in Ocala, Florida, in March 1993 and his nutrition based philosophy has taken Lange Eye Care to nine locations in Florida and is now one of the largest privately owned eye care centers in Florida. Retina care in Ocala, Gainesville, The Villages and all surrounding areas is something Lange Eye Care takes seriously. “You only have one set of eyes, so take care of them,” is Dr. Lange’s philosophy.

“Ask the Doctor”

Dr. Michael Lange is an endless crusader when it comes to educating the public as well as doctors. He can be heard daily on his syndicated talk show dispensing valuable information about eye health and total body health on “Ask the Doctor,” a popular talk show he has been hosting since 1993. He is also an avid lecturer to the public as well as to doctors at conferences; he is involved in many clinical studies utilizing the latest in technology to help the macular degeneration patients.

Early Detection of Macular Degeneration

All of the Lange Eye Care locations offer the most advanced technology to diagnose, follow and treat macular degeneration patients. This technology allows for very careful and accurate observation of retinal health. The key with macular degeneration is early detection. Once macular degeneration is detected then the appropriate customized plan can be developed for each patient. If you are looking for doctors that are trained in the very latest in prevention and treatment for macular degeneration in Ocala, Gainesville, The Villages, Williston, Inverness, Summerfield, Clearwater or surrounding areas come to one of the many Lange Eye Care locations.

Macular degeneration treatment in Ocala and retina care in Ocala is on SR 200 across from the Paddock Mall at Lange Eye Care Ocala. All of the newest technology for retina care in Ocala is available in both Ocala locations, the main office across from the mall and the West Ocala office in Triple Crown Plaza next to Oak Run. If you want to know about the very latest in macular degeneration treatment in Ocala then come to Lange Eye Care. Call 352 237 3768 or go to www.drmichaellange.com, or www.langeyecare.com.

Eye Vitamins for Macular Degeneration

Fortifeye 3 products Fortifeye™ and the ABCs of Ocular Nutrition

Dr. Michael Lange is also the founder and lead researcher for Fortifeye Vitamins, www.fortifeye.com. Fortifeye Vitamins is involved in the latest nutritional research for macular degeneration. Fortifeye Vitamins and Dr Michael Lange are utilizing the latest in intracellular blood studies to develop better and more bio-available vitamins for macular degeneration. Currently Fortifeye Macular Defense is being used by thousands of doctors and patients in an effort to slow down the visually devastating effects of macular degeneration. Patients can come to any Lange Eye Care location in Florida or call toll free 1 866 503 9746 to order one of the Fortifeye formulations.

Why wait? Call for an appointment for your macular degeneration treatment today!

Lange Eye Care Locations

Gainesville Office
Lange Eye Care and Associates
3968 SW Archer Road W101
Gainesville, Florida 32608
Phone: 352-376-6622

Ocala Office
Lange Eye Care and Associates
3101 SW College Road
Ocala, Florida 34474
Phone: 352-237-3768

Triple Crown Plaza Office
Lange Eye Care and Associates
11100 SW 93rd Court Road
Suite 15
Ocala, Florida 34481
Phone: 352-291-2000

Summerfield Office
Lange Eye Care Vision Outlet Center
Unit #604 Highway 441S
Summerfield, Florida
Phone: 352-307-3273

Inverness Office
Lange Eye Care and Associates
3808 E. Gulf to Lake Highway
Inverness, FL 34453
Phone: 352-344-5110

Clearwater Offices
Lange Eye Care Optical Gallery & LASIK Center
23666 U. S. Highway 19 North
Clearwater, FL 33765
Phone: 727-791-1214

Lange Sun and Nutrition Center
2551 Drew Street
Suite 302
Clearwater, FL 33765
Phone: 727-216-6275

Williston Office
Lange Eye Care And Associates
129 S. W. 7th Street
Williston, FL 32696
Phone: 352-528-0433

The Villages Office
Lange Eye Institute
466 and CR101
The Villages, Florida
Phone: 352-753-4014

 

 

 

 

Map and Directions


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More information: Dr. Michael P. Lange is a Board Certified Optometric Physician and a Certified Nutrition Specialist who started Lange Eye Care and Associates in Ocala, Florida, in March 1993. Lange Eye Care has grown to nine locations throughout the state of Florida with three Lasik centers. The Lange Eye Institute at The Villages in central Florida is home base for many of the nutritional studies that Fortifeye is involved in. Dr. Lange is one of the first doctors in the industry to utilize intracellular blood tests and blood absorption studies to improve the Fortifeye vitamin line. Dr. Lange travels the world for nutritional research gathering valuable information to continuously improve Fortifeye vitamin formulations. Dr. Lange is still involved in the clinical practice of eyecare. He is a guest lecturer, contributing author to many eyecare magazines, and a daily syndicated talk show host of ‘Ask The Doctor’ which broadcasts every weekday at 9am and Saturdays at 2pm from Tampa Bay on radio stations throughout the country and video streaming all over the world via the Internet.

 

 

 

Order Fortifeye™ vitamins by clicking below:

 

Fortifeye Complete Plus | Click To Order
Fortifeye Complete Plus | Click To Order
Fortifeye™ Complete Plus

Fortifeye™ Complete Plus is an advanced formulation based on the latest clinical studies. It is a combination of synergistically blended whole foods, phytonutients, vitamins, minerals, enzymes and essential fatty acids. When combined with proper diet, exercise and a healthy life style Fortifeye™ Complete Plus lays the foundation for good eye and total body health.

Dosage: 2 tablets + 1 softgel/day
30 Packs per box. Each daily pack contains 2 tablets and 1 softgel
Best price on the Internet! $50.00
Fortifeye Complete Plus | Click To Order

Fortifeye Super Omega-3 Fish Oil | Click To Order
Fortifeye Super Omega-3 Fish Oil
Fortifeye™ Super Omega 3 Fish Oil

Fortifeye™ Super Omega-3 Fish Oil is the newest, most concentrated and purified Omega Three Fish Oil by Fortifeye™
Features: Natural Triglyceride Form • Molecularly Distilled for Maximum Purity • High Potency/Triple Strength • Natural Orange/ Lemon Flavor • Pharmaceutical Grade • Superior taste • No unpleasant odor • Unsurpassed purity (Triple Molecular distillation) • Produced in Norway in the world’s only NSF, GMP certified Omega 3 production facility
Promotes: Heart Health • Brain Health • Eye Health • Joint Health • Circulation • Good Blood Pressure • Healthy Cholesterol • Improved Triglycerides • Skin, Hair & Nail Health • Mental & Cognitive Health

Take Fortifeye™ Super Omega-3 in conjunction with Fortifeye™ Complete Plus for more intensive nutritional therapy.

Dosage: 2 softgels/day
60 softgels/bottle
Best price on the Internet! $25.00
Fortifeye Super Omega-3 Fish Oil | Click To Order

Fortifeye FOCUS | Click To Order
Fortifeye FOCUS | Click To Order
Fortifeye™ FOCUS

Fortifeye™ FOCUS is a combination of three carotenoids—astaxanthin, lutein and zeaxanthin. Clinical studies indicate that 6mg of astaxanthin reduces eye fatigue symptomology and actually improves amplitude of accommodation, the eye’s ability to focus clearly on objects at near distances. This new formulation was developed to help reduce accommodative stress due to prolonged working at a near focal length. Fortifeye FOCUS is recommended for individuals who experience eye fatigue with near point tasks or after prolonged work on a computer. Fortifeye FOCUS can be used alone or in combination with any of the Fortifeye™ Vitamins.

Dosage: 1 softgel per day
30 softgels per bottle.
Best price on the Internet! $25.00
Fortifeye FOCUS | Click To Order

Fortifeye Complete One-A-Day | Click To Order
Fortifeye Complete One-A-Day | Click To Order
Fortifeye™ Complete
One-A-Day Multivitamin

Fortifeye™ Complete One-A-Day is a powerhouse combination of 50 total body and vision specific nutrients all combined into one USP certified tablet. Fortifeye™ Complete One-A-Day multivitamin has been created by doctors who understand that quality counts. Fortifeye™ Complete One-A-Day can be used alone or in combination with Fortifeye™ Super Omega 3 Fish Oil or Fortifeye™ Dry Eye Therapy Extreme to combat against free radical damage in the eyes and body.

Dosage: 1 tablet per day
30 tablets per bottle.
Best price on the Internet! $25.00
Fortifeye Complete One-A-Day | Click To Order

Fortifeye Complete Macular Defense | Click To Order
Fortifeye Macular Defense
Fortifeye™ Complete Macular Defense

Fortifeye™ Complete Macular Defense vitamins are the newest, most advanced nutraceuticals for your eyes and body, which provide purified Natural Triglyceride omega three fish oil, along with lutein and zeaxanthin for vision support. This formula provides the equivalent in antioxidant power to 15-17 servings of fruits and vegetables a day, 30 mg of lutein and 4.75 mg of zeaxanthin.

Dosage: 3 tablets + 1 softgel/day
30 Packs per box. Each daily pack contains 3 tablets and 1 softgel
Best price on the Internet! $70.00
Fortifeye Complete Macular Defense | Click To Order

 

 

All Fortifeye products are produced in a GMP, FDA and NNFA inspected facility that supplies products to the nutraceutical industry. Fortifeye is also approved by the Therapeutics Goods Association, the leading regulatory authority for nutraceuticals world wide and by NSF.

 

 

A Special Vitamin Formula For Dry Eye Syndrome

Fortifeye Dry Eye Extreme relieves symptoms of dry eyes, tired eyes and dry eye syndrome with triglyceride based omega-3 fish oil. Balance between omega-3 and omega-6 essential fatty acids, combination of vitamin D, black currant oil, and astaxanthin improves tear production and provides relief from dry, tired eyes and eye strain for computer users.

Michael P. Lange O.D. C.N.S. reviews new dry eye/ tired eye management with proper supplementation from Fortifeye Dry Eye Extreme, a new dry eye therapy that is doctor formulated and has been carefully designed to utilize the benefits of combining omega 3 fish oil, gamma linolenic acid (GLA) and astaxanthin. Available in 2012.

 

A Special Vitamin Formula By Fortifeye For Dry Eye Syndrome

New relief in dry eyes and tired eyes – Fortifeye Dry Eye Extreme for natural dry eye relief

Dry eye syndrome (keratoconjunctivitis sicca) is an imbalance between tear production and tear drainage. This condition affects nearly 60 million Americans.

Dr. Lange at the Norway fish oil factory, tweaking his formula.
Dr. Lange at the Norway fish oil factory, tweaking his formula.

What are dry eye symptoms? Eyes that are red, that feel sandy, gritty or burn, or that tear and itch can be symptoms of dry eyes. Fluctuation in vision, contact lens intolerance and recurrent infections can also be related to dry eyes. Dry red eyes, dry itchy eyes, dry sore eyes, dry burning eyes and dry tired eyes are oftentimes the chief complaints of patients coming into see an eye care provider, urgent care center or primary care physician.

Dry eye syndrome and the causes of dry, itchy eyes

Dry eye syndrome is often misdiagnosed as a form of conjunctivitis or pink eye and sufferers are put on unnecessary medications. Many patients with chronic dry eyes or severe dry eyes are looking for a magical cure for dry eyes and see a multitude of different eye and health providers in search for a dry eye cure. There is no cure for dry eye syndrome, however dry eye treatment can be initiated by an eye care provider and proper nutrition can help manage these chronic dry eye patients quite well. What are some examples of dry eye causes? Many things can cause dry eyes such as environmental factors, job, medications, contact lenses, systemic health problems, age and eye surgery. Currently, artificial tears and prescription topical medications are the gold standard for the treatment of dry eyes. In treating dry eyes it is important to address the entire system and not just treat topically. More and more evidence now suggests that proper nutrition may help to decrease the symptoms of dry eye and give significant dry eye relief.

“Dry eye symptoms will affect the majority of us at some time in our lives.”

A balance of omega-3 and omega-6 essential fatty acids, black currant oil, vitamins and astaxanthin

Dr. Lange inspecting the manufacturing facility for Fortifeye Super Omega-3 Fish Oil.
Dr. Lange inspecting the manufacturing facility for Fortifeye Super Omega-3 Fish Oil.

Oral supplementation with essential fatty acids (EFAs) via omega-3 fish oils and gamma linolenic acid (GLA) is now rapidly becoming an effective tool that optometrists and ophthalmologists are using in clinical practice to help with dry eyes. A synergistic balance between omega-3 and omega-6 EFAs seems to work best for dye eye patients. A lot of time and research on the benefits of omega-3, omega-6, GLA, astaxanthin and various other complementary nutrients has gone into the reformulation of Fortifeye’s newest product called Fortifeye Dry Eye Extreme.

Fortifeye’s first dry eye product was called Fortifeye Dry Eye Therapy and was used for years with great success, however the Fortifeye team consisting of physicians from all aspects of health care wanted to make a good thing even better. Fortifeye discontinued their current dry eye therapy product and developed a much more bioavailable and more concentrated omega three fish oil called Fortifeye Super Omega. This is a triglyceride based omega-3 fish oil with an EPA of 860 and DHA of 580 in two gel caps. This fish oil has been used successfully alone to help many dry eye patients with mild to moderate dry eye. Fortifeye decided to add some additional nutrients to further enhance the effects of the product and potentially help the moderate to severe dry eye patients. After careful research black currant oil, vitamin B6, vitamin B3, magnesium, vitamin C, vitamin D, zinc and a super carotenoid called astaxanthin were added to the Fortifeye Super Omega fish oil product creating Fortifeye Dry Eye Extreme.

Triglyceride based fish oil when combined with astaxanthin

Fortifeye Dry Eye Extreme is the first in the industry to use high levels of triglyceride based fish oil combined with GLA from black currant oil and astaxanthin. Astaxanthin is a relatively new nutrient used in supplements that comes from microalga Haematococcus pluvialis and is proving to have multiple health benefits. The carotenoid astaxanthin is the reason lobsters, shrimp and some crabs turn red when cooked. While it constitutes a tiny portion of farm-raised salmon feed (50 to 100 parts per million), astaxanthin represents up to 20 percent of the cost. Astaxanthin is an extremely potent antioxidant and anti-inflammatory. Clinical studies have now proven that 6mg of astaxanthin can improve the blood flow to the eye and actually aid in accommodation (focusing) and in reducing eye fatigue. Astaxanthin reduces inflammatory markers such as nitric oxide synthase (NOS), prostaglandin E2 (PGE2) and tumor necrosis factor (TNF). These remarkable aspects of astaxanthin are why Fortifeye Vitamins has incorporated it into their new dry eye vitamin formula called Fortifeye Dry Eye Extreme.

Fortifeye Dry Eye Extreme is a new dry eye therapy that is doctor formulated and has been carefully designed to utilize the benefits of combining omega 3 fish oil, gamma linolenic acid (GLA) and astaxanthin.
– Michael P. Lange O.D, C.N.S.

Vitamin D deficiency

Fortifeye Dry Eye Extreme is now recommended for patients with dry eyes and tired eyes. C-reactive protein (CRP) is a protein found in the blood, the levels of which rise in response to inflammation. Vitamin D deficiency is quite common in America. Patients with vitamin D deficiency are more prone to have elevated CRP and elevated TNF (tumor necrosis factor) and have an increased risk of inflammatory diseases in the body. Vitamin D deficiency is now being linked to many eye related problems. Vitamin D3 has been added to help quell this inflammation. Relatively new research has also indicated that vitamin C along with its antioxidant benefits is capable of lowering C-reactive protein as well. Because of this potential added benefit, vitamin C has also been added along with vitamin D3.

Triple molecularly distilled to remove PCBs and other pollutants

Research has found that high dietary intake of omega-3 EFAs (essential fatty acids) decreases the risk of dry eyes. One must be very careful today when increasing their levels of omega-3 EFAs by consuming more fish. PCBs (polychlorinated biphenyls) are persistent organic pollutants banned in 1979 but still present in ocean waters. Even fish that are caught in the Arctic regions can be contaminated due to the fact that airborne contaminants within the atmosphere will condense at lower temperatures and precipitate into this environment. Fish can be contaminated with mercury, lead, PCBs, dyes and other contaminants. Molecularly distilled fish oil is a convenient and safe way of getting the omega-3 EFAs and removing pollutants. We would never consider using fish oils that have not been refined to reduce contaminant levels to an undetectable amount.

The benefits of omega-3 fish oil to reduce inflammation

Dr. Lange and Dr. Eiji Yamashita, a world authority on a super carotenoid currently being utilized in new vitamin formulations.
Dr. Lange and Dr. Eiji Yamashita, a world authority on a super carotenoid currently being utilized in new vitamin formulations.

EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) are the two principal EFAs (essential fatty acids) found in fish known as omega-3 fatty acids. The current research suggests the anti-inflammatory effects of fish oil may help with dry eye syndrome. EPA generates the anti-inflammatory eicosanoids prostaglandin E3 and leukotriene B5. If the concentration of EPA is high enough the EPA blocks the delta-5 desaturase enzymatic step that stops the conversion of omega-6 EFAs to the inflammatory cascade of arachidonic acid (AA). This allows more conversion to anti-inflammatory prostaglandin E1 (PGE1). PGE1 then binds to EP2 and EP4 receptors to activate adenylate cyclase and increase cyclic AMP (adenosine monophosphate) which in turn stimulates a healthier tear production. The increase in omega-3 EFAs have also shown to improve dysfunction in the meibomian gland with a much thinner and clearer meibomian gland secretion thus helping with meibomian gland dysfunction. The increased consumption of a triple molecularly distilled and concentrated omega-3 fish oil will help to get the balance between omega-6 and omega-3 in better harmony and allows for less inflammation in the body and eyes. Americans have a much too high percentage of pro-inflammatory omega-6 in their diet. The addition of a good omega-3 fish oil is the start to a healthier body and visual system.

Dry eye syndrome (keratoconjunctivitis sicca) is an imbalance between tear production and tear drainage. This condition affects nearly 60 million Americans.

Omega-6 and astaxanthin for improved tear production

Liquid fish oil being filled into bottles.
Liquid fish oil being filled into bottles.

Gamma-linolenic acid (GLA) is an essential fatty acid (EFA) in the omega-6 family that is found mainly in plant seed oils. The three most common plant seed oils where GLA are found are borage seed oil, black currant oil and evening primrose oil. GLA is broken down in the body to dihomo-gamma-linolenic acid (DGLA) and arachidonic acid (AA). DGLA competes with AA and prevents the negative inflammatory effects that AA would otherwise cause. Adequate amounts of magnesium, zinc and vitamins C, B3 and B6 help to promote the conversion of GLA to DGLA rather than AA. Researchers in Japan have shown that astaxanthin may suppress the cyclooxygenase enzyme and decrease the amount of pro-inflammatory PGE2 produced. Once the AA pathway is blocked the DGLA is free to convert to anti-inflammatory prostaglandin E1 (PGE1) and stimulation of tear production occurs. Recent studies suggest that oral GLA supplementation improved dry eye both clinically and subjectively in patients with dry eye syndrome. Studies also show that patients who take a combination of linoleic acid (LA) and gamma-linoleic acid (GLA) prior to and after refractive surgery may have better tear production and less dry eye complications. Studies utilizing GLA and omega -3 fish oil have shown an additive anti-inflammatory effect with no elevation in arachidonic acid. Due to the extremely high amounts of omega-6 in most diets, Fortifeye has decided to use a ratio of approximately 10 to 1 omega-3 to omega-6 to maximize the anti-inflammatory effects and gain full advantage of both types of essential fatty acids. If the ratio of omega-6 (GLA) to omega-3 is too high in the omega-6 direction then the possibility of more inflammation related to the high omega-6 low omega-3 ratio exists.

Relief for dry eye sufferers through the latest research

The potential benefits for current and future dry eye sufferers from a carefully designed oral nutritional supplement for dry eye is huge. Fortify Vitamins Inc. has developed a synergistic blend of triple distilled omega-3 triglyceride based fish oil, plus gamma linolenic acid (GLA) from black currant oil, astaxanthin, vitamin D and other nutritional cofactors that is based on the latest research. This formula combines all of the latest developments in nutrition necessary to aid in the alleviation of signs and symptoms of dry eye syndrome and eye fatigue. Fortifeye Dry Eye Extreme is doctor-formulated and has been carefully designed to utilize these nutrients synergistically. Fortifeye vitamins are currently being used by thousands of patients around the world with great success. This formula is great for patients to use prior to and after Lasik and cataract surgery to help minimize post operative dry eye symptoms and inflammation. Many dry eye contact lens intolerant patients may benefit from using this supplement.

“Fortifeye Dry Eye Extreme could very well be the future of dry eye therapy.”
– Michael P. Lange O.D. C.N.S.

Computers users, eye strain and dry eye fatigue

A large population that may be helped from this new health supplement is the computer users. Computer use generates significant eye strain and dry eyes. Computer related dry eyes and eye fatigue ultimately leads to a condition called Computer Vision Syndrome (CVS). Fortifeye Dry Eye Extreme may be just what computer users have been waiting for.

The future therapy for dry and tired eyes

Patients who have been diagnosed with dry eye syndrome who want to be proactive in the health of their eyes should consider the natural approach at managing dry eyes with Fortifeye Dry Eye Extreme. This formula is being used clinically along with traditional medical treatment to help decrease the severity of many inflammatory eye problems. Fortifeye Dry Eye Extreme could very well be the future therapy for dry eye and tired eyes. Many patients that have dry mouth and chronic joint pain have also benefited from the nutrients in Fortifeye Dry Eye Extreme. Give it a try and see what it can do for you.

Multiple revisions in the formula of Fortifeye Dry Eye Extreme have delayed its release. We hope to have it available in early 2012.

Michael P. Lange, O.D.
Dr. Michael P. Lange
Board Certified Optometric Physician and Board Certified Nutritional Specialist

Dr. Michael P. Lange
Board Certified Optometric Physician
Certified Nutrition Specialist
Syndicated Daily Talk Show Host (Ask the Doctor)
www.langeeyecare.com
www.fortifeye.com
May 5, 2010

 

 

 

Author: Dr. Michael P. Lange is a Board Certified Optometric Physician and a Certified Nutrition Specialist who started Lange Eye Care and Associates in Ocala, Florida, in March 1993. Lange Eye Care has grown to nine locations throughout the state of Florida with three Lasik centers. The Lange Eye Institute at The Villages in central Florida is home base for many of the nutritional studies that inspired the Fortifeye Brand of vitamin supplements. Dr. Lange is one of the first doctors in the industry to utilize intracellular blood tests and blood absorption studies to improve the Fortifeye vitamin line. Dr. Lange travels the world for nutritional research gathering valuable information to continuously improve Fortifeye vitamin formulations. Dr. Lange is still involved in the clinical practice of eyecare. He is a guest lecturer, contributing author to many eyecare magazines, and a daily syndicated talk show host of ‘Ask The Doctor’ which broadcasts every weekday at 9 a.m. and Saturdays at 2 p.m. from Tampa Bay on radio stations throughout the country and video streaming all over the world via the Internet. Detailed information on the nutritional research Dr. Lange has been involved in, and the eye vitamins and whole body formulas he has formulated, are at www.Fortifeye.com. If you are looking for a great group of eye doctors in Florida go to www.LangeEyeCare.com. For more, read this article about Dr. Michael Lange, Ocala optometrist involved in research on nutrition and UV protection, or read this biography of Dr. Michael Lange, Ocala eye doctor (optometrist).

 


 

REFERENCES

Association for Research in Vision and Opthalmology (2003). Research Symposium Findings. Fort Lauderdale, Fla., May 4-9, program numbers 811, 2111, and 2112.

Barham JB et al (2000). Addition of EPA to GLA-supplemented diets prevents serun AA accumulation in humans Nutrition, August (130), 1925-31.

Barham JB, Edens MB, et al. Addition of Eicosapentanoic Acid to Gamma-linolenic acid? Supplemental Diets Prevents Serum Arachidonic Acid Accumulation in Humans. J of Nutrtion, 2001; 130: 1925-1931

Block G, Jensen CD, Dalvi TB, Norkus EP, Hudes M, Crawford PB, Holland N, Fung EB, Schumacher L, Harmatz P, Vitamin C treatment reduces elevated C-reactive protein. University of California, Berkeley, 94720, USA

Brown NA, et al (1998). Nutrition supplements and the eye. Eye, 12, 127-133.

J. Dyerberg, P. Madsen, J Moller, I. Aardestrup, E. B. Schmidt, Bioavailability of n-3 fatty acid formulations; N-3 Fatty Acids; Prevention and Treatment in Vascular Disease, 1995 : 217-226

Iwasaki & Tawara, (2006). Effects of Astaxanthin on Eyestrain Induced by Accommodative Dysfunction. Journal of Eye (Atarashii Ganka) (6):829-834.

Miljanovic B, Trivedi KA, Dana MR, et al. Relation between dietary n-3 and n-6 fatty acids and clinically diagnosed dry eye syndrome in women. Am J Clin Nutr. 2005;82:887-893.

Miyawaki et al., (2005). Effects of astaxanthin on human blood rheology. J. Clin. Therap. Med., 21(4):421-429.

Nagaki Y., et al., (2002). Effects of astaxanthin on accommodation, critical flicker fusions, and pattern evoked potential in visual display terminal workers. J. Trad. Med., 19(5):170-173.

Nagaki et al. (2005). The effects of astaxanthin on retinal capillary

Nagaki et al., (2006). The supplementation effect of astaxanthin on accommodation and asthenopia. J. Clin. Therap. Med., 22(1):41-54.

Nakamura et al. (2004). Changes in Visual Function Following Peroral Astaxanthin. Japan J. Clin. Opthal., 58(6):1051-1054.

Nitta et al. (2005). Effects of astaxanthin on accommodation and asthenopia – Dose finding study in healthy volunteers. J. Clin. Therap. Med., 21(6):637-650.

Ohgami et al., (2003). Effects of astaxanthin on lipopolysaccharide-induced inflammation in vitro and in vivo. Invest. Ophthal. Vis. Sci., 44(6):2694-2701.

Sawaki, K. et al. (2002) Sports performance benefits from taking natural astaxanthin characterized by visual activity and muscle fatigue improvements in humans. J. Clin. Ther. Med., 18(9):73-88.

Shimizu S et al (1991). Sesamin is a potent and specific inhibitor of delta 5 desaturase in polyunsaturated fatty acid biosynthesis. Lipids. Aug, 26(7), 512-6.

Shiratori et al. (2005). Effect of astaxanthin on accommodation and asthenopia – Efficacy identification study in healthy volunteers. J. Clin. Therap. Med., 21(5):543-556.

Suzuki et al., (2006). Suppressive effects of astaxanthin against rat endotoxin-induced uveitis by inhibiting the NF-kB signaling pathway. Exp. Eye Res., 82:275-281.

Takahashi & Kajita (2005). Effects of astaxanthin on accommodative recovery. J. Clin. Therap. Med., 21(4):431-436. blood flow in normal volunteers. J. Clin. Therap. Med., 21(5):537-542.

Thornton A (2003). Nutrients restore tear function in dry eye syndrome. Ophthalmology Times, May 12, special section.

Tobias Pischon, Susan Hankinson, Gokhan Hotamisligil, Nader Rifai, Walter Willett and Eric Rimm (2003) Habitual Dietary intake of omega-3 and omega-6 fatty acids in relation to inflammatory markers among US men and women. Circulation 2003; 108;155-160

Wu D, et al (1999). Effect of dietary supplement with black currant seed oil on the immune response of healthy elderly subjects. American Journal Clinical Nutrition, 70, 536-543.

 

 

Order Fortifeye™ vitamins by clicking below:

 

Fortifeye Complete Plus | Click To Order
Fortifeye Complete Plus | Click To Order
Fortifeye™ Complete Plus

Fortifeye™ Complete Plus is an advanced formulation based on the latest clinical studies. It is a combination of synergistically blended whole foods, phytonutients, vitamins, minerals, enzymes and essential fatty acids. When combined with proper diet, exercise and a healthy life style Fortifeye™ Complete Plus lays the foundation for good eye and total body health.

Dosage: 2 tablets + 1 softgel/day
30 Packs per box. Each daily pack contains 2 tablets and 1 softgel
Best price on the Internet! $50.00
Fortifeye Complete Plus | Click To Order

Fortifeye Super Omega-3 Fish Oil | Click To Order
Fortifeye Super Omega-3 Fish Oil
Fortifeye™ Super Omega 3 Fish Oil

Fortifeye™ Super Omega-3 Fish Oil is the newest, most concentrated and purified Omega Three Fish Oil by Fortifeye™
Features: Natural Triglyceride Form • Molecularly Distilled for Maximum Purity • High Potency/Triple Strength • Natural Orange/ Lemon Flavor • Pharmaceutical Grade • Superior taste • No unpleasant odor • Unsurpassed purity (Triple Molecular distillation) • Produced in Norway in the world’s only NSF, GMP certified Omega 3 production facility
Promotes: Heart Health • Brain Health • Eye Health • Joint Health • Circulation • Good Blood Pressure • Healthy Cholesterol • Improved Triglycerides • Skin, Hair & Nail Health • Mental & Cognitive Health

Take Fortifeye™ Super Omega-3 in conjunction with Fortifeye™ Complete Plus for more intensive nutritional therapy.

Dosage: 2 softgels/day
60 softgels/bottle
Best price on the Internet! $25.00
Fortifeye Super Omega-3 Fish Oil | Click To Order

Fortifeye FOCUS | Click To Order
Fortifeye FOCUS | Click To Order
Fortifeye™ FOCUS

Fortifeye™ FOCUS is a combination of three carotenoids—astaxanthin, lutein and zeaxanthin. Clinical studies indicate that 6mg of astaxanthin reduces eye fatigue symptomology and actually improves amplitude of accommodation, the eye’s ability to focus clearly on objects at near distances. This new formulation was developed to help reduce accommodative stress due to prolonged working at a near focal length. Fortifeye FOCUS is recommended for individuals who experience eye fatigue with near point tasks or after prolonged work on a computer. Fortifeye FOCUS can be used alone or in combination with any of the Fortifeye™ Vitamins.

Dosage: 1 softgel per day
30 softgels per bottle.
Best price on the Internet! $25.00
Fortifeye FOCUS | Click To Order

Fortifeye Complete One-A-Day | Click To Order
Fortifeye Complete One-A-Day | Click To Order
Fortifeye™ Complete
One-A-Day Multivitamin

Fortifeye™ Complete One-A-Day is a powerhouse combination of 50 total body and vision specific nutrients all combined into one USP certified tablet. Fortifeye™ Complete One-A-Day multivitamin has been created by doctors who understand that quality counts. Fortifeye™ Complete One-A-Day can be used alone or in combination with Fortifeye™ Super Omega 3 Fish Oil or Fortifeye™ Dry Eye Therapy Extreme to combat against free radical damage in the eyes and body.

Dosage: 1 tablet per day
30 tablets per bottle.
Best price on the Internet! $25.00
Fortifeye Complete One-A-Day | Click To Order

Fortifeye Complete Macular Defense | Click To Order
Fortifeye Macular Defense
Fortifeye™ Complete Macular Defense

Fortifeye™ Complete Macular Defense vitamins are the newest, most advanced nutraceuticals for your eyes and body, which provide purified Natural Triglyceride omega three fish oil, along with lutein and zeaxanthin for vision support. This formula provides the equivalent in antioxidant power to 15-17 servings of fruits and vegetables a day, 30 mg of lutein and 4.75 mg of zeaxanthin.

Dosage: 3 tablets + 1 softgel/day
30 Packs per box. Each daily pack contains 3 tablets and 1 softgel
Best price on the Internet! $70.00
Fortifeye Complete Macular Defense | Click To Order

 

 

All Fortifeye products are produced in a GMP, FDA and NNFA inspected facility that supplies products to the nutraceutical industry. Fortifeye is also approved by the Therapeutics Goods Association, the leading regulatory authority for nutraceuticals world wide and by NSF.

 

 

Lange Eye Care Locations

Gainesville Office
Lange Eye Care and Associates
3968 SW Archer Road W101
Gainesville, Florida 32608
Phone: 352-376-6622

Ocala Office
Lange Eye Care and Associates
3101 SW College Road
Ocala, Florida 34474
Phone: 352-237-3768

Triple Crown Plaza Office
Lange Eye Care and Associates
11100 SW 93rd Court Road
Suite 15
Ocala, Florida 34481
Phone: 352-291-2000

Summerfield Office
Lange Eye Care Vision Outlet Center
Unit #604 Highway 441S
Summerfield, Florida
Phone: 352-307-3273

Inverness Office
Lange Eye Care and Associates
3808 E. Gulf to Lake Highway
Inverness, FL 34453
Phone: 352-344-5110

Clearwater Offices
Lange Eye Care Optical Gallery & LASIK Center
23666 U. S. Highway 19 North
Clearwater, FL 33765
Phone: 727-791-1214

Lange Sun and Nutrition Center
2551 Drew Street
Suite 302
Clearwater, FL 33765
Phone: 727-216-6275

Williston Office
Lange Eye Care And Associates
129 S. W. 7th Street
Williston, FL 32696
Phone: 352-528-0433

The Villages Office
Lange Eye Institute
466 and CR101
The Villages, Florida
Phone: 352-753-4014

 

 

 

 

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More information: Dr. Michael P. Lange is a Board Certified Optometric Physician and a Certified Nutrition Specialist who started Lange Eye Care and Associates in Ocala, Florida, in March 1993. Lange Eye Care has grown to nine locations throughout the state of Florida with three Lasik centers. The Lange Eye Institute at The Villages in central Florida is home base for many of the nutritional studies that Fortifeye is involved in. Dr. Lange is one of the first doctors in the industry to utilize intracellular blood tests and blood absorption studies to improve the Fortifeye vitamin line. Dr. Lange travels the world for nutritional research gathering valuable information to continuously improve Fortifeye vitamin formulations. Dr. Lange is still involved in the clinical practice of eyecare. He is a guest lecturer, contributing author to many eyecare magazines, and a daily syndicated talk show host of ‘Ask The Doctor’ which broadcasts every weekday at 9am and Saturdays at 2pm from Tampa Bay on radio stations throughout the country and video streaming all over the world via the Internet.

 

 

 

Omega-3 Fish Oil, A Natural Treatment For Dry Eyes

Dr. Michael Lange on natural treatment for dry eyes and discussion of the metabolic pathways of omega-6 and omega-3 in regards to dry eye and health

There are some great nutritional approaches that may improve the treatment of dry eye syndrome, however most eye care providers, MDs, DOs and ODs are underutilizing this complimentary nutritional support for dry eyes.

Keeping an eye on Macular DegenerationFirst and foremost our diets and lifestyles need to be overhauled. In America our diets are caloric dense and nutrient deficient, consisting of way too much omega-6 fatty acids (oils from soy, corn, cottonseed, canola, sunflower and safflower), saturated fats and trans fats, thus increasing the chance of inflammation in our bodies. The typical western diet has too high an intake of omega-6 and too low an intake of omega-3 fatty acids; this is associated with increased levels of cytokines, proteins that trigger inflammation. Inflammation is one of the root causes of dry eye syndrome (keratoconjunctivitis sicca) and many other systemic diseases. Therefore we must decrease our consumption of processed foods, fast foods, canned foods, commercially raised beef, chicken, turkey and farm raised fish and eat more wild fish, free range chicken and turkey, free roaming organic grass fed beef, more fruits and vegetables (organically grown if possible), drink more filtered water and get plenty of good sleep and exercise. Sleep deprivation and sedimentary lifestyle are also contributing factors that increase cortisol levels, stress and inflammation in the body.

Take omega-3 fish oil for essential fatty acids

The simplest way to offset the imbalance between omega-6 and omega-3 in our diets is to eat fewer foods that are high in omega-6 and more foods that are high in omega-3 and increase your intake of omega-3 fatty acids from a good omega three fish oil supplement. The best source of omega three comes from marine sources like sardines, mackerel, wild salmon, anchovies, krill and squid. Alternative vegetable sources of omega three fatty acids are plankton/algae, chia seed oil and flax seed oil. The more bioavailable form of omega three essential fatty acids will come from the marine sources mentioned. The numerous health benefits of omega three fatty acids have been studied thoroughly, with subjects getting omega three fish oil from consuming more fish or taking a fish oil omega three supplement.

Triglyceride based fish oil vs. ethyl ester fish oil

Omega three fish oil comes in two readily available forms over the counter at the local drug store or health food store. Ethyl ester fish oil and triglyceride fish oil are the two forms that can be purchased OTC (over the counter). The ethyl ester version of fish oil is less expensive and is being recommended less and less by health care providers that are in tune with nutrition. However many physicians are not aware of the difference between the two types of fish oil and thus may be still recommending the cheaper less bioavailable ethyl ester form of omega three. Be careful when purchasing omega three fish oil at the local drugstore or warehouse club because they can be contaminated with unhealthy levels of PCBs and most contain ethanol. Most OTC omega three fish oils are ethyl ester based fish oil. The purification process uses ethanol to distill and concentrate the fish oil and the process to remove the ethanol after distillation is expensive. This additional processing expense to re-convert ethyl ester based fish oil back to the natural triglyceride form is the main reason companies are utilizing the ethyl ester version. Most fish oil that is associated with burping up a nasty fish taste is the ethyl ester version. The ethyl ester version has decreased absorption over triglyceride based fish oil and potential free radical damage exists with ethanol. Some studies have indicated that if ethyl ester fish oil is consumed with a high fat meal it will improve its absorption. Doesn’t ethanol cause dehydration too? So why in the world would anyone take ethyl ester fish oil, especially if they have dry eyes? Ethanol is an additive used in gasoline and is a fuel used in high performance race cars. It’s not something to put in your stomach. Fish oil should be consumed in the form that is found naturally in the sea, the natural triglyceride form. If you are not sure about the product you are taking, you can call the customer service number on the back of your fish oil supplement bottle and ask what form the fish oil is in. Small dosages of ethyl ester fish oil taken with food are probably relatively safe, but with more and more patients taking higher dosages of this form who knows what potential complications we could see in the future? Spend a little extra when purchasing an omega three fish oil and obtain the triglyceride form!

The Styrofoam test for ethyl ester based fish oil

A simple test you can perform at home is to squeeze your fish oil into a Styrofoam cup and see what happens after fifteen minutes. If the cup starts to melt, then it is the ethyl ester based fish oil. You may want to think twice about consuming it or giving it to your children or grandparents.

Newest triglyceride based fish oil – Fortifeye Super Omega

Fortifeye Super Omega-3 Fish Oil box imageLearn about Fortifeye Super Omega triglyceride based fish oil at www.fortifeye.com. If you have access to wild Alaskan salmon, eat it at least three times per week or more, or consume more of the small fish like sardines or anchovies. Be careful and try not to eat any large predatory type fish due to the potential contaminants in their flesh like PCBs, organophosphates, mercury and lead. Eating more cold water fish or taking a good triglyceride based fish oil supplement will increase the omega-3 content in your body and help with your overall health as well as improve dry eyes. Take a good triglyceride based fish oil, not ethyl ester fish oil. The triglyceride based fish oil Fortifeye Super Omega has almost 900 EPA and 600 DHA in two gel caps. I recommend moderate to severe dry eye patients to take four Fortifeye Super Omega pills for the first six weeks and then reverting to two pills thereafter. However, if they have elevated triglycerides, arthritis, severe dry eyes or other health issues they may benefit by staying on four pills a day if recommended by their health care provider.

A good omega three fish oil is anti-inflammatory

There are many dry eye formulas on the market that have relatively low amounts of omega three fish oil combined with all kinds of natural anti-inflammatory nutrients, like curcumin, boswellia, ginger, while willow bark, nettles etc. –one must be careful with these! These nutrients are good for acute inflammatory conditions but not for long term use, since they will act as a COX-2 inhibitor and block the cyclooxygenase enzymes which are responsible for the bad pro-inflammatory prostaglandin PGE2 and the good anti-inflammatory benefits of series three prostaglandin PGE3! A prostaglandin is any member of a group of lipid compounds that are derived enzymatically from fatty acids and have important functions in the body. These natural COX-2 inhibitors block the good and the bad. PGE2 creates inflammation, however sometimes we need the PGE2 to cause inflammation in the healing process so we don’t want to block these long term, and we certainly don’t ever want to block the benefits of omega three fish oil, the anti-inflammatory series 3 prostaglandins PGE3. Adequate production of series 3 prostaglandins may protect against heart attack, stroke, arthritis, lupus and asthma, and new research may be proving it is beneficial for dry eye syndrome and macular degeneration. Keep in mind that the COX-2 inhibitors like Viox and Celebrex have gained a lot of negative media attention due to potential unwanted health complications. A much better way to help dry eyes and total body health is to maximize the body’s anti-inflammatory ability by giving it the nutrients necessary to do this. We do not want to potentially hinder the positive omega-3 fish oil benefits by using these natural COX-2 inhibitors long term. Omega three fatty acids from fish oil supplements are the best way to stimulate this PGE3 and help reduce inflammation in the body and eyes. For instance, arachidonic acid is a polyunsaturated omega-6 fatty acid which controls a wide variety of bodily functions, especially those functions involving inflammation and the central nervous system. The EPA in fish oil actually has the ability to block the delta 5 desaturase enzyme (D5D) that is responsible for the inflammatory cascade of arachidonic acid in the omega 6 metabolic pathway.

Benefits of triglyceride based omega three fish oil

There are many positive health benefits of a good source of EPA and DHA via omega 3 triglyceride based fish oil. You can start to become proactive in the health of your eyes and body by getting the benefits of fish oil from a good quality triple molecular distilled triglyceride based omega three fish oil. Many patients with dry eyes will notice improvements in their dry eye symptomatology simply by adding the correct triglyceride based omega three fish oil to their diet.

Metabolic pathways of essential fatty acids

Another way to improve the metabolic pathways of essential fatty acids is to make sure the delta-6 desaturase enzyme (D6D) is working correctly. Alpha-linolenic acid is an organic compound found in canola, soybeans, walnuts, chia and flaxseed oil. D6D is crucial in the omega-3 conversion of alpha-linolenic acid (ALA) to stearidonic acid and ultimately EPA and DHA. D6D is also crucial in the omega-6 conversion of linoleic acid (LA) to gamma-linolenic acid (GLA) which ultimately turns into good anti-inflammatory series one prostaglandin PGE1. A few specific vitamin and mineral cofactors that are extremely necessary for these conversions utilizing D6D are B3, B6, C, zinc and magnesium. Trans fats, saturated fats, alcohol intake, sugar, diabetes, poor pituitary function, low thyroid function, cancer, Sjögren’s syndrome, scleroderma, ulcerative colitis, Crohn’s, liver cirrhosis, elevated cholesterol and immune dysfunction also can inhibit this conversion. As you can see there are many roadblocks that may interfere in the delta 6 desaturase enzyme system in both omega-6 and omega-3 metabolic pathways. This is why ALA (flax seed oil) is oftentimes a poor source of omega three EPA and DHA and why linoleic acid (an unsaturated omega-6 fatty acid found in corn, safflower and sunflower oil) converts oftentimes to the more inflammatory prostaglandins PGE2 instead of PGE1. Consuming more omega-3 from fish oil supplements (or a good fish source versus plant source) will bypass the entire D6D and D5D pathways in the omega-3 metabolism and allow for much more efficient and quicker utilization of EPA and DHA to the anti-inflammatory PGE3 and LTB5 (anti-inflammatory leukotriene, a lipid that suppresses inflammatory tissue reactions in the body) thus reaping the total health and ocular benefits.

Under optimal conditions adults can make both DHA and EPA from ALA but these optimal conditions are quite rare in today’s society. Conversion of omega-3 from plants into long chain omega-3 fatty acids found in marine sources is very low. Very minimal amounts of EPA and virtually no DHA are formed from supplemental alpha linolenic acid. So consume more omega-3 via fish oil versus vegetable source ALA. In order to bypass the D6D in the omega-6 pathway and make it more efficient GLA is needed. GLA is found in borage oil, black currant seed oil, evening primrose oil and blue green algae. GLA will then convert to DGLA which ultimately converts to anti-inflammatory PGE1 or pro-inflammatory PGE2.

Healthy diet plus a good omega three fish oil

Following a lifestyle including a proper diet (like the hunter gatherer or Mediterranean diets, from the era before humans suffered from diseases of civilization), consuming more omega-3 (from fish or products like Fortifeye Super Omega), reducing your omega-6 intake and taking a good multi-vitamin (like Fortifeye Complete One-a-Day) may increase the conversion of DGLA to PGE1 and decrease the conversion down the arachidonic pathway to PGE2 and LTB4 (pro-inflammatory leukotrienes). PGE1 is a good prostaglandin, has potent anti-inflammatory benefits and may help with overall health and better tear secretion. The combination of a good omega three fish oil like Fortifeye Super Omega and GLA may improve overall health and dry eye syndrome. You will have to combine this with the proper diet and hydration. Remember, more is not better-too much GLA may actually increase arachidonic acid and inflammation from PGE2-so always take GLA with triglyceride based fish oil, and not without it.

Lastly one must eat foods with a low GI (glycemic index) and decrease high GI foods such as potatoes, white pasta, white bread and white rice. This will stop the pancreas from secreting fluctuating amounts of insulin. Elevated insulin, due to lots of refined carbohydrates, will stimulate more conversion of GLA into the pro-inflammatory pathway of arachidonic acid and thus more of the bad prostaglandins PGE2 and LTB4.

Reduce inflammation and improve dry eye symptoms

So in review, eat a ‘hunter gatherer type of diet’. This means lots of fresh vegetables and fruits, nuts and seeds, wild fish, grass fed organically raised beef, organically raised poultry and whole grains. Eliminate or reduce processed foods, refined foods, fast foods, sodas, sugar and salt. Drink plenty of filtered water, green tea and red wine in moderation. Take a good multivitamin like Fortifeye Complete One-A-Day or Fortifeye Complete Plus, take two to four Fortifeye Super Omega pills daily (or an equivalent omega three fish oil) at different times of the day with food, take a GLA supplement at the same time you take one of the fish oil supplements, and get some exercise and a good night of sleep. Obviously, see your local eye care provider as well.

Michael P. Lange, O.D.
Dr. Michael P. Lange
Board Certified Optometric Physician and Board Certified Nutritional Specialist
If you will do the things discussed in this article you may be helping to reduce inflammation in your body, extend and improve your quality of life and have less dry eye related problems.

Dr. Michael P. Lange
Board Certified Optometric Physician
Certified Nutrition Specialist
Syndicated Daily Talk Show Host (Ask the Doctor)
www.langeeyecare.com
www.fortifeye.com
May 2, 2010

 

 

Author: Dr. Michael P. Lange is a Board Certified Optometric Physician and a Certified Nutrition Specialist who started Lange Eye Care and Associates in Ocala, Florida, in March 1993. Lange Eye Care has grown to nine locations throughout the state of Florida with three Lasik centers. The Lange Eye Institute at The Villages in central Florida is home base for many of the nutritional studies that inspired the Fortifeye Brand of vitamin supplements. Dr. Lange is one of the first doctors in the industry to utilize intracellular blood tests and blood absorption studies to improve the Fortifeye vitamin line. Dr. Lange travels the world for nutritional research gathering valuable information to continuously improve Fortifeye vitamin formulations. Dr. Lange is still involved in the clinical practice of eyecare. He is a guest lecturer, contributing author to many eyecare magazines, and a daily syndicated talk show host of ‘Ask The Doctor’ which broadcasts every weekday at 9 a.m. and Saturdays at 2 p.m. from Tampa Bay on radio stations throughout the country and video streaming all over the world via the Internet. Detailed information on the nutritional research Dr. Lange has been involved in, and the eye vitamins and whole body formulas he has formulated, are at www.Fortifeye.com. If you are looking for a great group of eye doctors in Florida go to www.LangeEyeCare.com. For more, read this article about Dr. Michael Lange, Ocala optometrist involved in research on nutrition and UV protection, or read this biography of Dr. Michael Lange, Ocala eye doctor (optometrist).