How To Pick A Good Omega Three Fish Oil

Dr Michael P Lange on how to pick a good omega three fish oil. Learn about the natural triglyceride form of fish oil versus ethyl ester fish oil. The omega three fatty acids provided in Fortifeye Super Omega fish oil help to maintain a healthy omega-3 to omega-6 ratio in the body. For best results, take a natural triglyceride based fish oil similar to that found in wild salmon.

How To Pick A Good Omega Three Fish Oil

Michael P. Lange OD, CNS

Omega three is quite a buzz word lately.

The world is going through an omega three explosion. You hear about the positive health benefits from increased consumption of omega three fatty acids on talk shows, advertisements, health food stores, drug stores, the Internet and from your friends and physicians. There are so many different means of obtaining omega three fatty acids that it becomes quite confusing. Currently the best and most bioavailable form of omega three fatty acids is derived from marine sources. Fish oil, krill oil and squid oil (calamari) have the highest most bioavailable forms of omega three fatty acids. Fish oil currently has by far the most clinical research linking the positive health benefits to omega three out of the three mentioned. The shelves at the supermarket, health food stores and drug stores are filled with different brands, concentrations and derivatives of omega three fish oil. The typical consumer can become very confused when attempting to purchase an omega three fish oil while relying on a store clerk with very little education to make a recommendation.

All omega three fish oils are not created equal!

It is essential to consume only the highest quality, purest omega three fish oil for optimal health. Recently Good Morning America made the public aware of the potential contaminants that are in certain fish oil products sold over the counter. Currently there is an ongoing lawsuit aimed at some fish oil companies and drug stores that are selling products that had potentially health threatening amounts of contaminants like PCBs in their oils. PCBs (polychlorinated biphenyls) are persistent organic pollutants banned in 1979 but still present in ocean waters. One should only purchase omega three fish oil that has been thru a molecular distillation refining process to reduce any potential contaminants.

The most reputable and experienced fish oil processing plants are in Norway

Make sure your fish oil is coming from a state of the art production facility based in Norway. The facility should be GMP certified and NSF certified as well. In addition to NSF and GMP certification, the plant should be drug licensed by the Norwegian health authorities. These are the highest standards for regulating fish oil factories. Look for something on the bottle that says “Product of Norway”.

What types of fish are being used for the fish oil?

The highest quality omega three fish oils are derived from wild caught, non threatened small plankton feeding anchovies, sardines and mackerel from the deep clear pacific waters off the coast of South America. Harvesting these types of fish promotes a truly eco-friendly and sustainable marine source. These are relatively small and young fish that have a higher percentage of omega three fatty acids and are characterized by especially low levels of environmental impurities. If the fish oil label states the oil is coming from fish that are caught off the coast of Norway, or in pristine Norwegian waters, or in the Atlantic Ocean, think twice about purchasing that product. That statement is very misleading since the Norwegian factories are processing and purifying the crude oil that is sent to them from the fish caught in the Southern Hemisphere. They are not catching the fish in the Norwegian waters. Norwegian salmon are not wild salmon, they are usually farm raised. Stay away from farm raised salmon since they potentially can be high in pro-inflammatory fats called omega six and can be deficient in omega threes. The reddish orange color of a wild salmon comes from natural astaxanthin while the orange color in farm raised salmon comes from synthetic astaxanthin. You should be careful when purchasing salmon oil unless you know it is coming from wild caught Alaskan salmon. Ask to see an independent analysis of the fish oils, especially if using salmon oil. A-linolenic acid (ALA), which are omega three fatty acids derived primarily from vegetable sources, should be at less than one percent (average .85) in wild Alaskan salmon, while farmed salmon contain an average of 2 to 2.5% as a result of the composition of feed they are eating, according to a paper published by J Molkentin in European Food Research and Technology (2007). This research revealed a method for distinguishing organically farmed salmon from wild Atlantic salmon. The omega three to omega six ratio is different in farm raised versus wild salmon as well. And new research showed that, compared with farmed salmon, wild salmon had a much more favorable omega-3/omega-6 ratio:

  • Farmed Atlantic salmon had an omega-3/omega-6 ratio of 6.5 to 1(26% omega-3 fat / 4.4% omega-6 fat).
  • Wild Atlantic salmon had an omega-3/omega-6 ratio of 19 to 1(26.7% omega-3 fat / 1.4% omega-6 fat).

Smell and taste is extremely important

If something doesn’t smell or taste good, the consumer will not consume it. High quality fish oil will have a very pleasant smell and taste whether it is in liquid form or in a gel cap. The refining process has great impact on smell and taste. Pure unrefined products often times have a very unpleasant sensory characteristic. If you bite into a gel cap and the oil smells and tastes rancid, think twice about taking it since the quality may be questionable. Make sure only natural flavoring is used and no artificial sweeteners are used to improve taste. Read the label. The Norwegians have done extensive research in the development of a good tasting natural fish oil.

Using an eco-friendly sustainable food source is recommended when looking for a good fish oil

The definition is: “Sustainable development is development that meets the needs of the present without compromising the ability of future generations to meet their own needs.” The use of anchovies, sardines and mackerel for omega three fish oil is truly to use an eco-friendly and sustainable source.

Make sure the fish oil has gone through molecular distillation to refine and eliminate any potential contaminants

A triple molecular distillation process will ensure the highest purity. Independent third party contaminant analysis of each batch should be routinely done. Most reputable fish oil companies can make an analysis available to the consumer with some advanced notice. If the fish oil is not molecularly distilled it may have hazardous levels of contaminants like PCBs. Oils that are not refined will very likely contain trace allergens. People with seafood allergies can react to unrefined oils.

Two types of readily available omega three fish oils are ethyl ester and triglyceride

The natural triglyceride form of fish oil should go thru molecular distillation to purify the oils. A typical natural triglyceride form of fish oil will have a concentration of about 180 EPA and 120 DHA. The synthetic ethyl ester version uses ethanol in the distillation and concentration process during transesterification to produce a higher concentration of EPA and DHA. During this process the natural triglyceride backbone is replaced with an ethyl ester backbone. This produces a fairly pure and highly concentrated omega three fish oil. This concentrated form of fish oil can obtain 450 EPA and 300 DHA in one capsule. In order to convert the ethyl ester back to the more natural triglyceride form, one more step of transesterification must be done to replace the ethyl ester based backbone with a triglyceride backbone the way it occurs naturally in ocean fish. Many fish oil companies will not go that extra step due to cost! It is almost 50% more expensive to go through this final step to convert the synthetic ethyl ester fish oil back to more natural triglyceride based fish oil. Almost all of the leading authorities on omega three fish oil will agree that the triglyceride form is more stable and bioavailable over the cheaper synthetic ethyl ester version. Most patients using this triglyceride form of fish oil will have fewer problems with burp back of the nasty fish taste common to some fish oils. Ethanol is a free radical and ethanol can potentially cause free radical damage in the body. The amount of ethanol in this form of fish oil is relatively low (.1%-.5%) but certain groups of populations should be avoiding ethanol completely. You can do a quick test at home to see what type of fish oil you have. If fish oil eats thru a Styrofoam cup in thirty minutes or less, this may be related to the ethanol content. Spend a little extra money and ensure you are getting the most concentrated bioavailable form of fish oil, and take only triglyceride based fish oil. If it doesn’t say natural triglyceride or TG form, then it is probably ethyl ester based. Certain European countries like Denmark do not allow the sale of ethyl ester fish oil over the counter, only the triglyceride form. Ethyl ester fish oil in these countries is controlled with prescription. The overall cost per absorption ratio makes the concentrated triglyceride form of fish oil a better value than the ethyl ester version.

Introducing Fortifeye Super Omega-3 Fish Oil

Fortifeye Super Omega-3 Fish Oil box image
Fortifeye Super Omega-3 Fish Oil

Hopefully this helps the consumer and the doctor when looking for and recommending omega three fish oil for its numerous health benefits. Omega three fatty acids are a necessity, not an option for optimal health. Don’t wait. Be proactive in your future health and start taking a good omega three fish oil today! Fortifeye Vitamins has created Fortifeye Super Omega to fulfill everything discussed in this article. Fortifeye Super Omega is produced by one of the most experienced teams in the industry, in the world’s only NSF and GMP certified state of the art fish oil production facility located in Brattvaag, Norway. Fortifeye Super Omega is an ultra-refined high potency natural triglyceride form of omega three fish oil. Fortifeye Super Omega is consumer friendly with great taste and smell and minimal if any burp back. It was also developed as a chewable for those who have difficulty swallowing pills. Fortifeye Super Omega is being used throughout the world with enormous success. The Fortifeye Vitamin team routinely travels the globe to meet with the world’s leaders in nutrition to further enhance their product line. The Fortifeye team has just returned in May 2010 from a ten day research trip to the Norwegian Coast, where they met with some of the world’s leaders in omega three fatty acid production and research. Following this trip, some of the advisors in research and development for Fortifeye will be traveling to Europe for the International Vitamin Conference. Fortifeye stays actively involved in continuous research for the enhancement of their products. Fortifeye Vitamins is currently in the development stages for a new liquid triglyceride based fish oil for kids and adults. They are also in the final phases of development of an omega three based dry eye supplement called Fortifeye Dry Eye Extreme. You can purchase Fortifeye Super Omega or any of the Fortifeye antioxidants through many eye care and health care providers, or go to Omega three fish oil when combined with proper diet, exercise and lifestyle adjustments can be very powerful at promoting wellness.

Dr. Michael P. Lange Board Certified Optometric Physician Certified Nutrition Specialist Syndicated Daily Talk Show Host (Ask the Doctor) May 23, 2010

Author: Dr. Michael P. Lange is a Board Certified Optometric Physician and a Certified Nutrition Specialist who started Lange Eye Care and Associates in Ocala, Florida, in March 1993. Lange Eye Care has grown to nine locations throughout the state of Florida with three Lasik centers. The Lange Eye Institute at The Villages in central Florida is home base for many of the nutritional studies that inspired the Fortifeye Brand of vitamin supplements. Dr. Lange is one of the first doctors in the industry to utilize intracellular blood tests and blood absorption studies to improve the Fortifeye vitamin line. Dr. Lange travels the world for nutritional research gathering valuable information to continuously improve Fortifeye vitamin formulations. Dr. Lange is still involved in the clinical practice of eyecare. He is a guest lecturer, contributing author to many eyecare magazines, and a daily syndicated talk show host of ‘Ask The Doctor’ which broadcasts every weekday at 9 a.m. and Saturdays at 2 p.m. from Tampa Bay on radio stations throughout the country and video streaming all over the world via the Internet. Detailed information on the nutritional research Dr. Lange has been involved in, and the eye vitamins and whole body formulas he has formulated, are at If you are looking for a great group of eye doctors in Florida go to For more, read this article about Dr. Michael Lange, Ocala optometrist involved in research on nutrition and UV protection, or read this biography of Dr. Michael Lange, Ocala eye doctor (optometrist).


Fortifeye™ and the ABCs of Ocular Nutrition

Improve your retinal health by taking Fortifeye vitamins and utilizing acetyl L carnitine, alpha lipoic acid, gogi berry, and green tea. Learn about ORAC value, antioxidant power, endothelial growth factor, cardiovascular disease, avoiding beta carotene. Reduce the risk of cardiovascular disease by taking omega-3 essential fatty acid from omega three fish oil. Lutein increases macular pigment density and reduces wet macular degeneration.

Fortifeye™ and the ABCs of Ocular Nutrition
Fortifeye Vitamins
Fortifeye Vitamins

Right Ingredients.  Right Science.  Right for You.

“…promote proper vision and whole body health with the right ingredients at the right levels.”

The entire family of Fortifeye products has been created by doctors who understand that quality counts. Each nutrient was chosen based on the highest manufacturing standards and uptake ability by the body.

All Fortifeye products are produced in a GMP, FDA, NNFA and NSF approved facility that supplies products to the domestic nutraceutical industry. On a global basis Fortifeye is manufactured in an approved TGA facility, the leading regulatory authority for nutraceuticals world wide.


Vitamin A: back to top

A fat-soluble, antioxidant vitamin important for vision and bone growth, belonging to the family of chemical compounds known as retinoids. Night blindness – the inability to see well in dim light – is associated with a deficiency of vitamin A. This vitamin is needed for the formation of rhodopsin, a retinal pigment. Vitamin A is also needed for the development of a healthy cornea. Third world countries have a high percentage of Vitamin A deficiencies and need supplementation for the pregnant mothers and children. However most developed countries where the population is consuming animal proteins, fruits and vegetables are not deficient in Vitamin A and do not need to supplement. Vitamin A can build up in toxic levels in the body and cause liver problems, birth defects, osteoporosis, neurological problems and many other potential problems. Too much vitamin A may be linked to increased risk of macular degeneration. Since vitamin A deficiency is rare in the populations that are taking Fortifeye vitamins and the potential for vitamin A toxicity exists, Fortifeye has decided to take all vitamin A and beta carotene out of their supplements.

Vitamin B complex: back to top

Eight water-soluble vitamins that play important roles in cell metabolism.

Vitamin C: back to top

Right Ingredients. Right Science. Right for You.(L-ascorbic acid) The most widely taken dietary supplement, Vitamin C is an essential water soluble nutrient required in small amounts to allow a range of essential metabolic reactions. Vitamin C is required for the synthesis of collagen and to maintain healthy skin, tendons, ligaments, blood vessels, cartilage and teeth. Vitamin C is an antioxidant that protects the body against oxidative stress, and is needed as a coenzyme in many reactions. Recent studies suggest that higher vitamin C intake may be associated with reduction in heart disease, strokes, cancers, cataracts and rheumatoid arthritis and excessive amounts of vitamin C may be associated with increase in oxalates that may increase risk of kidney stones. New research indicates that supplementing with vitamin C reduces C-reactive protein (CRP), an inflammatory marker linked with an increased risk of cardiovascular disease, stroke, peripheral artery disease, diabetes and possibly macular degeneration. It may lower CRP as much as statin drugs without the potential side effects. Vitamin C was one of the nutrients in the AREDS study that was beneficial for macular degeneration. High dosages of vitamin C may be beneficial at lowering intraocular pressure in patients with glaucoma.

Vitamin D: back to top

Is a group of fat-soluble pro hormones in two main forms; D2 (meritocracies) and D3 (collectable). Vitamin D is naturally produced by the human body when exposed to sunlight. Vitamin D regulates calcium and phosphorus levels in the blood by promoting their absorption from food in the intestines, and by promoting re-absorption of calcium in the kidneys. It also promotes bone formation and internalization. Vitamin D affects the immune system by promoting interspersion, phagocytes, and anti-tumor activity. After Vitamin D is produced in the skin from sun exposure or consumed in food it is converted in the liver and kidneys to the active form called clairol and then is released into circulation to specific organs. Vitamin D deficiencies are now being linked to several diseases including hypertension, diabetes, tuberculosis, cancer, periodontal disease, multiple sclerosis, collagen vascular diseases, seasonal affective disorder, depression, Parkinson’s and macular degeneration. New science (NHANES III) indicates that patients with higher serum levels of vitamin D may reduce the risk of macular degeneration. Vitamin D has anti inflammatory properties associated with it that may prove beneficial to many health and eye related diseases including macular degeneration. More studies on the use of vitamin D3 and eye disease will be necessary to prove these beneficail aspects. Twenty minutes of sun exposure in fair skinned people (3 to 6 times longer in dark skinned) between 12 and 2 p.m. will produce approximately 10,000 IU’s of vitamin D3. Physicians are now recommending more sun exposure or additional Vitamin D thru foods or vitamins for the high risk populations: elderly, darkly pigmented people, patients on medications that may block the absorption of fat soluble vitamins and people that are not in the sun very often. It is a good idea to have blood calcidiol (25-hydroxy-vitamin D) levels measured especially if you are in a high risk group. This is a current classification level that can give you some guide lines:

• 0-14.9 ng/mL = Severely deficient
• 15.0-31.9 ng/mL = Mildly deficient
• 32.0-100.0 ng/mL = Optimal
• >100.0 ng/mL = Toxicity possible

Vitamin E: back to top

A fat-soluble vitamin in eight forms that is an important antioxidant. Naturally occurring vitamin E exists in eight chemical forms (alpha-, beta-, gamma-, and delta-tocopherol and alpha-, beta-, gamma-, and delta-tocotrienol).The natural forms are usually labeled with the letter “d” (for example, d-gamma-tocopherol), whereas synthetic forms are labeled “dl” (for example, dl-alpha-tocopherol). Of the eight forms, alpha-tocopherol is traditionally recognized as the most active form of vitamin E but new studies suggest that gamma tocopherol exhibits the anti-inflammatory effects. Vitamin E may help prevent or delay coronary heart disease by limiting the oxidation of LDL-cholesterol. Vitamin E may help prevent the formation of blood clots which could lead to a heart attack. It is one of the five nutrients in the AREDS study used to slow down the progression of macular degeneration. Some studies have linked vitamin E as having protective effects on the human lens and macula. New studies indicate that tocotrienols may be effective at inhibiting angiogenesis and having numerous other health benefits. This may prove in the future to be beneficial in diabetic retinopathy and wet macular degeneration. Vitamin E may also help decrease C-Reactive protein which is a risk factor for cardiovascular disease, stroke, peripheral artery disease, diabetes and macular degeneration.

Acai Fruit Extract:  back to top

Acai is a fruit that grows on a particular palm tree in the Amazon rainforest. It is classified as one of the “super fruits” due to its very high ORAC value. Acai has a very high concentration of anthocyanins, antioxidants, fiber, omega essential fatty acids, plant sterols, vitamins and minerals. This nutrient dense fruit has been associated with tremendous health benefits. Fresh acai berries have an ORAC value of about 16,700 per 100 grams, while freeze dried varieties of acai berry can have ORAC as high as 100,000 per 100 grams.

Acetyl-L-carnitine (ALCAR):  back to top

Acetyl-L-carnitine is the acetylated ester of the amino acid L-carnitine. This form much more readily crosses the blood brain barrier than the L-carnitine form and aids in the conversion of fat to energy. ALCAR has been shown in clinical studies to support and improve mitochondrial functioning especially when combined with alpha lipoic acid. Some studies suggest that ALCAR may improve mental clarity, cognition, memory and energy. ALCAR may prove useful in Parkinson’s, Alzheimer’s, depression, diabetic neuropathy and blood sugar control, heart disease, lung disease and macular degeneration. Early studies may prove the combination of ALCAR, COQ-10 and omega three essential fatty acids may have protective effects on macular degeneration.

Alpha-lipoic acid: back to top

An antioxidant postulated to be effective in preventing vitamin C and vitamin E deficiency. It is able to scavenge reactive oxygen species and reduce other metabolites, such as glutathione, maintaining a healthy cellular redox state. Lipoic acid has been shown in cell culture experiments to increase cellular uptake of glucose, suggesting its use in diabetes. Recent studies now suggest that alpha-lipoic acid combined with acetyl-L-carnitine may improve memory and support mitochondrial health. These new studies hypothesize that alpha lipoic acid could benefit dementia and Parkinson’s. Some studies indicate it may be useful in glaucoma patients.

Biotin (B7): back to top

Used in cell growth, the production of fatty acids, metabolism of fats, and amino acids. It plays a role in the Krebs cycle, the process in which energy is released from food. Biotin not only assists in various metabolic chemical conversions, but also helps with the transfer of carbon dioxide. Biotin is also helpful in maintaining a steady blood sugar level.

Bilberry: back to top

Bilberry (European blueberry) is a deep blue fruit with high levels of anthocyanin pigments that have been linked to multiple health benefits. In several studies, bilberry was shown to improve visual acuity at night as well as shortening the time to adapt to dark conditions and recover from glare – important for light-sensitive individuals during night time driving. New science suggests bilberry, like blueberries, may prove to be a potent inhibitor of VEGF and may be helpful in diabetic retinopathy, macular degeneration, heart disease and cancer. Bilberry has an ORAC value of approximately 9,000 per 100 grams.*

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Research has shown increasing intake of antioxidants such as dark green leafy vegetables and dark berries may reduce the risk of macular degeneration and cataracts. Kale and spinach are very high in lutein, a carotenoid that increases macular pigment density in the retina that may have some protection against macular degeneration. Lutein also acts as an internal sunscreen to the retina by absorbing the harmful HIV (blue light) rays from the sun. Lutein may be beneficial at slowing down cataract formation. Blueberries have many health benefits. Studies are proving that blueberries decrease risk of cancers, reduce LDL cholesterol, guard against neurological diseases, relieve arthritis, strengthen immune system, promote urinary tract health and optimize ocular health. New research using blueberries has revealed inhibition of VEGF which may help in the protection of certain cancers, proliferative diabetic retinopathy and the wet stage of macular degeneration. The ORAC value of blueberry is about 6,552 per 100 grams, ORAC of kale is about 1,770 and the ORAC value of spinach is about 1515.

Boron: back to top

A naturally occuring element, boron has been shown to decrease excretion of calcium and activate estrogen and vitamin D. This may retard bone loss as you age and decrease the risk of osteoporosis.

Bromelain:  back to top

Found in abundance in pineapples, bromelain is not a single substance, but rather a collection of enzymes and other compounds. It is a mixture of protein-digesting enzymes called proteolytic enzymes or proteases. Bromelain is an anti-inflammatory agent. In addition to aiding in blood clot formation, it has also been proposed in the use of arthritis treatment. It aids in the absorption of quercetin (flavonoid). Super high dosages of bromelain may cause rapid heart beat.

Fortifeye™ Vitamins are the newest, most advanced nutraceuticals for your eyes and body. Compare Fortifeye to your current vitamins.

Calcium: back to top

A naturally occurring element, calcium is responsible for bone growth and maintenance. Calcium uptake by the body is known to decrease with age, weakening bones (osteoporosis), but calcium supplementation seems to slow that process.

Carotenoids: back to top

Substances that enable the body to synthesize retinoids. Carotenoids are organic pigments that are naturally occurring in plants and certain animals. New studies are now proving that beta-carotene may block the absorption of lutein. Lutein is a beneficial carotenoid that may improve the health of the macula. Beta-carotene may also increase the risk of lung cancer in smokers. New science suggests beta-carotene may increase risk of aggressive prostate cancer. Due to all the negative science regarding supplemental beta-carotene, Fortifeye Vitamins decided to remove all beta-carotene from their formulas.

Chromium:  back to top

An elemental metal which is thought to even out blood sugar metabolism, potentially helpful for diabetic patients. It is also a powerful antioxidant in one form.

Cinnamon Bark Extract:  back to top

Cinnamon has been used for thousands of years as a spice and for medicinal purposes. Cinnamon has been used as an aid in the common cold, help digestive problems and often used as an antimicrobial. More recently cinnamon has been useful in helping to control glucose, cholesterol and triglycerides in type 2 diabetics. Cinnamon has an ORAC score of 267,536 per 100 grams making it one of the most powerful antioxidants in the world. The numerous health benefits related to diabetes combined with the high antioxidant power makes cinnamon bark extract very appealing for total body as well as ocular health.

Cocoa Extract: back to top

Cocoa is the dried and fermented bean from the cacao tree where chocolate comes from. Cocoa is high in two specific flavanoids – epicatechins and polyphenols. The flavanoids from cocoa have been associated with many health benefits. Cocoa may improve circulation to the brain and heart and thus improve cardiovascular health and improve cognitive abilities. Cocoa may also be beneficial at lowering blood pressure and lowering LDL (bad cholesterol) and raising HDL (good cholesterol). The antioxidant power (ORAC Value) of cocoa is one of the highest of any food on the planet. The high amounts of antioxidant in cocoa may help to retard free radical damage in the body and slow down the age related degenerative diseases in the body and eyes. ORAC value of dry powdered cocoa is about 80,000 per 100 grams and dark chocolate has an ORAC value of approximately 13,000 per 100 grams.

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Naturally occurring, copper is used by the body along with zinc to maximize iron uptake. Copper is an essential nutrient to all humans. It is found primarily in the bloodstream, as a cofactor in various enzymes. Copper is one of five nutrients in the AREDS study used to help slow the progression of macular degeneration.

CoQ10 (Ubiquinone):  back to top

Coenzyme Q10 is an oil soluble vitamin-like antioxidant found in every cell in the body. The highest concentration is found in the mitochondria. The primary function is generating energy. CoQ10 levels decrease with age, certain medications and certain diseases. CoQ10 has been associated with health benefits in numerous diseases like: heart disease, diabetes, gum disease, Parkinson’s, cancer, macular degeneration and glaucoma. CoQ10 deficiencies have been linked to certain medications like statins, beta blockers and tricyclic antidepressants. New studies indicate that CoQ10 combined with omega three fish oil and acetyl-L-carnitine may have protective effects for macular degeneration. Good dietary sources of CoQ10 are salmon, sardines, herring, tuna and mackerel. CoQ10 is best taken with a meal to aid in absorption.

Cyanocobalamin (B12):  back to top

B12 is the most chemically complex of all vitamins. It is involved in the metabolism of every cell in the body and is crucial in DNA and fatty acid synthesis. Elevated homocysteine can be linked to B12 deficiency along with pernicious anemia. New
studies indicate that low B12 status may increase risk of cognitive impairment. B12 deficiency becomes more of a problem as we age and in true vegetarians. Since it is difficult for the elderly population to absorb B12, larger amounts of B12 are now being used in vitamin supplements to help decrease the chances of patients developing B12 deficiencies.

Docosahexaenoic acid (DHA):  back to top

An omega-3 essential fatty acid, DHA is most often found in fish oil. DHA is a major fatty acid in sperm and brain phospholipids, and especially in the retina. Dietary DHA can reduce the level of blood triglycerides in humans, which may reduce the risk of heart disease. Low levels of DHA cause reduction of brain serotonin levels and have been associated with ADHD, Alzheimer’s disease, and depression, among other diseases, and there is mounting evidence that DHA supplementation may be effective in combating such diseases. May be beneficial for macular degeneration and dry eyes. The DHA used in Fortifeye vitamins comes from the highest quality ultra purified triglyceride based fish oils. This natural form of fish oil maximizes absorption, has no after taste and is toxin free. New science is now proving that omega three may decrease the shortening of the end cap of a chromosome know as a telomere. Telomere shortening is seen as an indicator of biological aging, so omega three fish oil should be incorporated into any healthy anti-aging diet.

Eicosapentaenoic acid (EPA):
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An omega-3 essential fatty acid, found most notably in oily fish. EPA is a polyunsaturated fatty acid that acts as a precursor for prostaglandin-3, which inhibits platelet aggregation. EPA is thought to be effective in lowering inflammation. May be beneficial for macular degeneration and dry eyes. Recent studies have suggested that EPA may affect depression and suicidal behavior. EPA may prove to be beneficial for breast cancer, as well as aid in treatment of multiple myeoloma. The EPA used in Fortifeye Vitamins comes from the highest quality (triple molecular distillation) triglyceride based fish oils. This natural form of fish oil maximizes absorption, has no after taste and is toxin free. New science is now proving that omega three may decrease the shortening of the end cap of a chromosome know as a telomere. Telomere shortening is seen as an indicator of biological aging, so omega three fish oil should be incorporated into any healthy anti-aging diet.

Folic acid (B9): back to top

Folic acid or B9 is extremely important during periods of rapid cell division and growth. This B vitamin is needed to produce healthy red blood cells and prevent anemia. Folic acid is essential for healthy homocysteine levels and in the prevention of neural tube defects in infants. Folic acid when combined with B12 and B6 will bring homocysteine levels down. New studies also indicate the combination of B12, folic acid and B6 will decrease the development of macular degeneration. Folic acid is extremely important and you don’t want to have a deficiency, however
there is a fine line between too little and too much. Too much folic acid is associated with cognitive decline and increased risk of certain types of cancer. General consensus as of 2010 is not to take more than 1000mcgs from natural and synthetic sources. Fortifeye Vitamins has cut back the amount of folic acid in their products to make sure the public doesn’t get too much from supplementing.

Gamma-linolenic acid (GLA):
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An omega-6 essential fatty acid found primarily in vegetable oils such as evening primrose (oenothera biennis) oil, blackcurrant seed oil, or borage oil. From GLA, the body forms dihomo-gamma-linolenic acid (DGLA). This is one of the body’s three sources of eicosanoids (along with AA and EPA.) DGLA is the precursor of the prostaglandin PGH1, which in turn forms PGE1 and the thromboxane TXA1. PGE1 has a role in regulation of immune system function. GLA is unique among the omega-6 polyunsaturated fatty acids (linoleic acid, GLA, and arachidonic acid) in its potential to suppress tumor growth and metastasis. GLA may also improve tear production and aid dry eyes. GLA by stimulating PGE1 acts as an anti-inflammatory
as well.

Gogi berry: back to top

Gogi berry, or llycium berry, has been used for thousands of years in traditional Chinese medicine. Gogi berry has been named the “anti-aging berry” because of its nutrient dense profile and extremely high antioxidant power. Gogi berry is considered one of the “super fruits” since it has one of the highest ORAC scores of any edible fruit. The ORAC value of 100 grams of gogi is approximately 25,300. Gogi berry may be the richest source of zeaxanthin in the plant family. Studies reveal that intake of a modest daily amount of gogi berries markedly increases fasting plasma zeaxanthin levels. This aids in improving macular pigment density which may prove to be beneficial for macular degeneration. Early studies indicate that gogi berry may have some neuro protective qualities in protecting retinal ganglion cells in glaucoma. The gogi berry may also aid in dark adaptation. The gogi berry is a good source of essential and trace minerals, amino acids, vitamins, polysachrides and essential fatty acids. The nutritional value of the gogi berry is proving to be beneficial for ocular and overall health.

Grape seed extract:  back to top

Used extensively in Europe, grape seed extract is rich in polyphenols, compounds that have antioxidant properties some consider even greater than vitamin C and vitamin E. Beyond its antioxidant powers, it is thought to improve blood circulation and help strengthen blood vessels. It may reduce the risk of cardiovascular disease and cancer. Resveratrol is one of the polyphenols found in grape seeds that has enormous health benefits.

“Since the body does not produce all of the required elements for optimal health, supplements are critical for your best health.”

Green tea extract:  back to top

EGCG, a key antioxidant found in green tea, is thought to support retinal health and works particularly well when in presence of Vitamin E. According to researchers at the University of Kansas, EGCG is 100x more powerful as an antioxidant that Vitamin C and 25x more powerful than Vitamin E. EGCG may also inhibit the formation of new blood vessels (anti-VEGF); this may prove to be useful in supporting retinal health. Green tea has been linked to lower cancer risk, lower cholesterol, faster weight loss, neuro protection, improved cognitive abilities, healthier immune system, better diabetic control and may benefit arthritis. 100 grams of brewed green tea has an ORAC value of approximately 1253. There is some evidence that green tea may help slow down cataracts. New science is proving that green tea may slow down the degeneration of the end cap of the chromosome called a telomere. This makes green tea an anti-aging nutrition.

Hesperidin: back to top

A flavonoid glycoside that has been shown to reduce cholesterol and blood pressure experimentally. In some studies large doses of the glucoside hesperidin were shown to decrease bone density loss. Hesperidin has also been shown to have anti-inflammatory effects.

Iodine: back to top

A chemical element that is required in trace amounts by most living organisms, iodine is necessary for proper production of thyroid hormone.

Lutein:  back to top

A carotenoid found naturally in dark green leafy vegetables (spinach and kale) and other natural sources, this potent antioxidant is sorely lacking in the typical American diet. Lutein and zeaxanthin are the only carotenoids found in the retina of the eye. Lutein supplementation has been shown in landmark clinical studies to increase macular pigment density which may promote macular health. Scientists believe lutein helps filter out dangerous ‘blue’ light, helping to maintain the photoreceptor and retinal health. Lutein is now believed to have a protective effect on the retina and may help to slow down age related macular degeneration. Lutein may have some protective effects against cataract formation. Lutein is more readily available when greens are gently cooked or juiced versus the raw state.

“Clinical studies have shown that increasing supplemental intake of lutein increases macular pigment density in the retina. Low levels of macular pigment is common in patients with macular degeneration.”

Lycopene: back to top

A bright red carotenoid pigment, lycopene is a phytochemical found in tomatoes and other red fruits. Lycopene is the most common carotenoid in the human body and is one of the most potent carotenoid antioxidants. Studies indicate it may reduce the risk of cardiovascular disease, cancer, diabetes, osteoporosis, male infertility and even macular degeneration.

Magnesium: back to top

The chemical element required in trace amounts by the body for the basic nucleic acid catalysis. Magnesium is necessary to maintain the health of almost every organ in the body especially the heart, muscles, kidneys, bones and teeth. Found most notably in spinach, pumpkin seeds and halibut. Magnesium has shown promise in treating symptoms of autism and ADHD, when combined with vitamin B6. There is an association between low magnesium intake and diabetes. Studies indicate that consumption of magnesium may lower C-reactive protein and other signs of chronic inflammation. Inflammation is one of the root causes of many eye diseases.

Manganese: back to top

Elementally found in nature, manganese and in its various ionic states (II) function as cofactors for a number of enzymes.

Mangosteen fruit extract:  back to top

Mangosteen is grown in Southeast Asia and is considered one of the super fruits. Mangosteen is known as the “queen of tropical fruits” and is very high in polyphenols, xanthones and tannins. Mangosteen is known for its health promoting properties and has a high ORAC score. Research indicates that xanthones may support the immune system, maintain intestinal health, help stop free radical damage, and support cartilage, joint and respiratory health.

Molybdenum: back to top

A transition metal important in plant nutrition, and is necessary in animal and human nutrition. It is found at the active site of certain enzymes, including xanthine oxidase, important within the eye.

N-Acetylcysteine: back to top

A co-factor which aids glutathione to increase uptake and efficacy of free radicals as antioxidants. N-Acetylcysteine may be beneficial in certain types of cancer, COPD, bipolar disorders, schizophrenia, boosting the immune system, aiding in detoxification of the body, reducing duration of influenza and may help with chronic blepharitis and symptoms associated with dry eyes.

Niacin (B3):   back to top

A water-soluble vitamin which plays an essential role in energy metabolism in the living cell and DNA repair. It also plays a role in removing toxic and harmful chemicals from the body. Niacin, when taken in large doses, increases the level of high density lipoprotein (HDL) or good cholesterol in blood. New studies are using niacin as a vasodilator to improve circulation in patients that have experienced a vein occlusion in the eye.

Pantothenic Acid (B5):  back to top

A water-soluble vitamin required to sustain life and is critical in the metabolism and synthesis of carbohydrates, proteins, and fats.

Phosphorous:  back to top

An element (always found as a compound in nature) that is a component of DNA and RNA and essential for all living cells where it forms part of the structural framework of these molecules (ADP, ATP).

Pomegranate fruit extract:  back to top

Pomegranate known as the “royal fruit” is a rich source of antioxidants and polyphenols. Pomegranate has a moderate ORAC value of about 2,860 per 100 grams. Some of the health benefits claims of pomegranate are improved circulation to the heart, reduction of arterial plaque, reduction in blood pressure and LDL (bad cholesterol), protective effects for breast and prostate cancer, improvement in erectile dysfunction and may act as an anti-inflammatory. The antioxidant power, improvement in circulation and anti-inflammatory aspects of pomegranate may prove to be beneficial for good ocular health.

Pyridoxine (B6):  back to top

B6 is required for the synthesis of neurotransmitters and red blood cells. It is also necessary for healthy homocysteine levels. Supplementation with pyridoxine, folic acid and B12 reduces the concentration of homocysteine in the bloodstream. Elevated homocysteine is a risk factor for heart disease, stroke, macular degeneration and occlusive artery disease in the eye. Super high dosages of B6 may cause nerve damage in the legs and arms.

Quercetin dehydrate:  back to top

A flavinoid found in such food as citrus and apples, quercetin may have positive effects in combating or helping to prevent cancer, heart disease, cataracts, allergies, inflammations, and certain respiratory conditions. Patients should make their doctors aware if taking high dosages of quercetin prior to antibiotic therapy.

Resveratrol:  back to top

Found in the skin of red grapes, resveratrol is perhaps one of the most potent antioxidants known. Research shows that resveratrol has anti-vascular endothelial growth factor (anti-VEGF) which they believe offers the greatest degree of protection to human blood-vessel cells, particularly within the retina. New studies indicate it may increase life span. Resveratrol may be useful as a chemo-protectant, cardio-protectant, anti-inflammatory, neuro-protectant and may prove useful for diabetes. Fortifeye was one of the first in the industry to utilize resveratrol in their formulas.

“Current studies show that certain nutrients can actually slow or stop the development of unwanted blood vessels (called vascular endothelial growth factor, or “VEGF”). Therefore, nutrients with anti-VEGF properties such as green tea, resveratol, turmeric, and soy isoflavones are tremendously important for overall ocular health, particularly for diabetics or patients with macular degeneration.”

Riboflavin (B2):
back to top

Required for a wide variety of cellular processes; like the other B vitamins, it plays a key role in energy metabolism. Riboflavin is required for the metabolism of fats, carbohydrates, and proteins. Deficiencies can cause corneal and lenticular opacities.

Rutin: back to top

A citrus flavonoid glycoside and antioxidant. It has been suggested that rutin might play an important role in inhibiting some cancers, as well as strengthening the capillaries, including those in the choroid. Rutin is also an inhibitor of VEGF which may prove useful in diabetic retinopathy and wet macular degeneration.

Selenium: back to top

A trace element not naturally produced by the body, selenium is found in high concentration in nuts. Selenium functions as cofactor for reduction of antioxidant enzymes such as glutathione peroxidases and thioredoxin reductase.

Sesame lignans: back to top

Powerful antioxidants that have been shown to work within the essential fatty acid derivatives (GLA) to create positive enzymatic reaction as compared to negative prostaglandin reactions. Sesame lignans help to block the inflammatory cascade of arrachidonic acid inherent to omega six oils.

Taurine: back to top

Compound that in recent laboratory studies have shown that taurine can influence (and possibly reverse) nerve blood flow, motor nerve conduction velocity, and nerve sensory threshold defects. In certain animal cases, the absence of taurine causes central retinal degeneration.

Thiamine (B1): back to top

Plays an important role in helping the body convert carbohydrates and fat into energy. It is essential for normal growth and development and helps to maintain proper functioning of the heart and the nervous and digestive systems. Thiamine is water-soluble and cannot be stored in the body. However, once absorbed, the vitamin is concentrated in muscle tissue.

Turmeric (Curcumin): back to top

Naturally occurring in turmeric, curcumin is in curry spice. Curcumin is known for its anti-inflammatory, chemoprotective, antioxidant, anti-amyloid and anti-VEGF (anti-vascular endothelial growth factor) properties. Studies indicate this compound may be beneficial in inflammatory diseases in the eye and may prove to be effective in slowing down certain types of cataracts. New studies indicate it may decrease chances of developing dementia.

“Thousands of patients are currently using Fortifeye Complete Plus combined with proper diet and exercise to dramatically improve their quality of life.”


Vanadium: back to top

A trace metal most popularly added to drinking water in Asia. It has been suggested that vanadium improves blood sugar control, and increases muscular strength, as well as osteoporosis treatment.

Zeaxanthin:  back to top

Zeaxanthin is one of the two carotenoids contained within the retina of the eye. Zeaxanthin and lutein have an almost identical chemical structure and have similar properties. Zeaxanthin, like lutein, increases macular pigment density and also helps to filter out the harmful blue light from the sun. Gogi berries have one of the highest sources of zeaxanthin and orange bell peppers are relatively high in zeaxanthin and more readily available. Zeaxanthin may also have some protective effects on cataract formation. Zeaxanthin may inhibit VEGF and prove useful for diabetic retinopathy and wet macular degeneration.

Zinc: back to top

A trace metal, zinc is an activator of certain enzymes, such as carbonic anhydrase, important in the transport of carbon dioxide in blood. Clinical studies have found that zinc, combined with antioxidants and certain vitamins (A, C, and E) may delay progression of age-related macular degeneration. Also, significant dietary intake of zinc has also recently been shown to impede the onset of flu. Fortifeye Vitamins uses Opti Zinc to gain superior absorption and bio availability over other forms of zinc.


IMPORTANT NOTE: These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent disease.

Fortifeye Vitamins
Fortifeye VitaminsRight Ingredients.  Right Science.  Right for You.™


The new i.Scription® technology by Zeiss

The new i.Scription® technology is explained by Dr Michael Lange, Ocala optometrist. Have you ever picked up your brand new pair of glasses and they just were not right? Your vision seemed blurry especially at night, a lot of glare coming off of lights, difficulty adapting to the new prescription because things seemed distorted or blurry?

The future of eye care is here today at Lange Eye Care Optical Gallery and Lasik Center in Clearwater, Florida

Michael P. Lange OD, CNS

The new i.Scription® technology is explained by Dr. Michael Lange, Ocala optometrist

The i.Profiler automatically measures both eyes in just under a minute
The i.Profiler automatically measures both eyes in just under a minute
The diagnostic screen of the i.Profiler provides a more accurate prescription
The diagnostic screen of the i.Profiler provides a more accurate prescription

Have you ever picked up your brand new pair of glasses and they just were not right? Did your vision seemed blurry especially at night, or was there a lot of glare coming off of headlights while driving? Are you having difficulty adapting to the new prescription because things seemed distorted or blurry, or your eyes had a pulling sensation or you point blank could not get used to your new glasses? Well, this is a fairly commonplace in the optical industry. There are many potential reasons for not having a good spectacle prescription and having these adaptation issues. Maybe the doctor was going too quickly through the refractive process and the prescription was not correct to begin with? It is very important that the prescription the doctor derives from the refraction is accurate. It is possible that the optician in the optical did not take the correct measurements for your pupillary distance (PD) or maybe the seg height (placement of the bifocal segment) of your new progressive lens wasn’t measured accurately. The frame that was picked may not be correct for the particular prescription the doctor ordered. It is also possible when wearing a progressive lens that the particular progressive lens brand is not adequate for the particular frame that was picked for the job or the lifestyle of the patient or customer. So you can see there are a lot of variables when having a pair of glasses made. Human error is just about always involved in the process of determining the correct prescription for glasses and then in the proper measurements and the manufacturing of those spectacles. It wasn’t until recently that we had much of a choice.

The i.Profilerplus® and i.Terminal™ are used in an innovative new diagnostic procedure by Zeiss which reduces human error

Eye exams using i.Profiler, the starting point for the unique i.Scription concept.
Eye exams using i.Profiler, the starting point for the unique i.Scription concept. The screen shows a personalized visual profile for your eyes. Yellow corresponds to the ideal eye shape. Other colors show exactly where your eye deviates from the norm.

Carl Zeiss Vision Inc., one of the leaders in eyecare and lens technology, is leading the way in new technology to minimize human error and obtain a much more accurate prescription for spectacles. Lange Eye Care Optical Gallery and Lasik Center in Clearwater, Florida, has the latest advancements in refractive technology developed by Zeiss. Lange Eye Care is one of the first eye care centers in the country to have this new and exciting refractive system called i.Scription®  technology . The i.Profilerplus® is an all-in-one automated system that measures the refractive status of the patient, auto keratometry readings, corneal topography and wave front aberrometry in a matter of seconds. This information is then sent to a computer in the examination room for the doctor to use to determine a super customized i.Scription. The i.Scription is measured and written in 1/100th of a diopter increments (current technology only allows .25 diopter increment), allowing for a super customized prescription to maximize the clarity of a patient’s eyesight with their new prescription. The new i.Profiler technology takes higher order aberrations into consideration when calculating this new precise i.Scription. Higher order aberrations are small imperfections in the visual system that cause potential glare and decreased vision more often in dim illumination and at night. Now the doctors at Lange Eye Care have the ability to give you an i.Scription that will be written in 1/100th of a diopter increments. This prescription may improve your night vision dramatically and help to eliminate some eye fatigue. The additional cost to having the i.Scription performed is minimal and the additional benefits for many patients are dramatic. Ask one of the doctors at the Clearwater Lange Eye Care if you are a good candidate for this new i.Scription.

Get the world’s most accurate prescription glasses – the Zeiss Individual™ progressive lens only at Lange Eye Care Optical Gallery and Lasik Center in Clearwater, Florida

Human error is minimized with the new i.Profiler in the calculations of the i.Scription and now human error is also minimized with the addition of the i.Terminal™. The i.Terminal is another advanced piece of technology that allows for extremely accurate measurements for your Zeiss Individual™ progressive lenses.

i.Terminal by ZEISS
The i.Terminal by ZEISS allows the patient to see how they will look with their new glasses - before putting them on!

This new technology takes precise measurements of pupillary distances, fitting heights, pantoscopic angle, vertex distance and frame wrap. It also allows the patient to review photo images while wearing specific frames to help determine which frame fits and looks best. The i.Terminal also provides demonstrations of lens enhancements to the patient or customer. The combination of the i.Profiler and the i.Terminal minimizes any human error and determines the most accurate prescription possible for your new super customized free-form back surface Zeiss Individual™ lenses. Lange Eye Care is leading the way in advanced refractive technology and taking patients into the future. Let’s face it, we all want to see as perfectly as possible. So the question is why wouldn’t you want to have an i.Scription? If you haven’t been satisfied with the spectacle correction you have, or vision isn’t as sharp as you think it should be, or you see glare around lights, or you do a lot of work in dim illumination or at night, you should consider coming to the Lange Eye Care Optical Gallery and Lasik Center in Clearwater, Florida, and seeing if the i.Scription technology is right for you.

Dr. Michael P. Lange
Board Certified Optometric Physician
Certified Nutrition Specialist
Syndicated Daily Talk Show Host (Ask the Doctor)
September 5 2010

Author: Dr. Michael P. Lange is a Board Certified Optometric Physician and a Certified Nutrition Specialist who started Lange Eye Care and Associates in Ocala, Florida, in March 1993. Lange Eye Care has grown to nine locations throughout the state of Florida with three Lasik centers. The Lange Eye Institute at The Villages in central Florida is home base for many of the nutritional studies that inspired the Fortifeye Brand of vitamin supplements. Dr. Lange is one of the first doctors in the industry to utilize intracellular blood tests and blood absorption studies to improve the Fortifeye vitamin line. Dr. Lange travels the world for nutritional research gathering valuable information to continuously improve Fortifeye vitamin formulations. Dr. Lange is still involved in the clinical practice of eyecare. He is a guest lecturer, contributing author to many eyecare magazines, and a daily syndicated talk show host of ‘Ask The Doctor’ which broadcasts every weekday at 9 a.m. and Saturdays at 2 p.m. from Tampa Bay on radio stations throughout the country and video streaming all over the world via the Internet.

Colbee Burris from Zeiss, Dr. Michael Lange and David Junkins from Zeiss all discuss the latest in in i.Scription technology and the latest in lens technology on Dr Lange’s daily talk show “Ask the Doctor” out of the Clearwater Lange Eye Care Optical Gallery and Lasik Center.

Introducing ZEISS i.Scription® lenses

i.Scription® optimization by Carl Zeiss Vision analyzes the human eye to the nearest one hundredth of a dioptre. Used in conjuction with the i.Profiler® system, optimised visual performance in corrective lenses is obtained.

Enjoy optimised visual performance with the new ZEISS Customized lenses using i.Scription® technology.

Innovative lenses are the focal point of Carl Zeiss Vision. A special highlight is the i.Scription® solution which combines traditional subjective refraction and wavefront measurement into a new refraction technique. In conjunction with a new method of lens optimization, the highly exact refraction data leads to unparalleled precision. The measurements are no longer performed to the nearest one quarter, but to the nearest one hundredth of a dioptre. All – including higher order – aberrations are taken into account, providing wearers with a whole new experience in vision. The high level of patient satisfaction and the wide degree of acceptance by opticians underline the excellence of i.Scription®. Carl Zeiss Vision offers the i.Scription® optimization as an additional option for practically all ZEISS lenses.

i.Scription® is a comprehensive product concept. The key to the decisively improved performance of lenses featuring i.Scription® is an examination technique new to the field of optometry, combined with innovative methods of lens design and production. By incorporating aspects of human vision never taken into account before, the wearer experiences a new dimension of visual quality.

The basis of the i.Scription® lens design is the combination of subjective refraction and the data obtained with the innovative i.Profiler® measuring system. It analyzes the human eye with a high degree of precision. It provides detailed information on the imaging properties of the eye, in particular features such as higher order aberrations that influence vision in unfavourable lighting conditions.

Carl Zeiss Vision has developed a totally new method of optical computation for the technical design of the lenses. The “secret” behind i.Scription® is an optimization algorithm which determines the lens values to the nearest one hundredth of a dioptre on the basis of the data provided by the optician. The resulting spectacle lenses provide the wearer with optimised visual performance, particularly in difficult lighting and contrast conditions, in twilight and at night.

In many cases the incorporation of additional information in the lens design can lead to a considerable improvement in vision. During the test phase, lens values which clearly deviated from the previous prescription were calculated for some wearers. Ametropes who only used their spectacles occasionally in the past because they were dissatisfied with their prescription are now convinced spectacle wearers. A number of wearers who used to feel unsure when driving in poor light also experienced major improvements.

The i.Scription® optimization is already available in a large number of Relaxed Vision Centres equipped with an i.Profiler® system. You can find opticians’ addresses and further information at:

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